Common Names: kitchen sage
Limited research exists on interventions for reducing oral discomfort in palliative care patients, making it important for improving their quality of life.
Ethanolic extract of SO leaves showed concentration-dependent inhibitory effects on cancer cell viability, survival, migration, and 3D spheroid formation. Potential source of chemotherapeutics against HPV-16+ cervical cancer.
Scientists extracted three key compounds from the herb Salvia officinalis which effectively combat Staphylococcus aureus, a major cause of bovine mastitis. These compounds inhibit biofilm formation and disrupt existing biofilms, showing promise for alternative therapies in dairy farming.
A study found that environmentally friendly sage extract has high antioxidant properties, DNA damage reduction, and potential neuroprotective effects, making it beneficial for preventing/treating inflammatory and oxidative stress-induced conditions.
Hyssop and sage extracts were used to make silver nanoparticles with antifungal properties, showing potential as eco-friendly fungicides for agriculture. Sage extract had larger particles, while hyssop extract was more effective against fungus, especially.
Nanoparticles made with sage extract showed high antioxidant and antimicrobial activity, especially when supported on STb silica. The study demonstrates the potential of these materials for antimicrobial applications in both dark and light conditions.
Study evaluated essential oils for antimicrobial activity against biofilms on dental acrylic resin. EOs of and showed higher action than standard treatments. EOs could be effective in reducing biofilm on dental acrylic resin.
CA from and is a powerful antioxidant and anti-inflammatory compound that protects mitochondria in brain cells, potentially aiding in cytoprotection and mitochondrial renewal through Nrf2 activation and regulation of mitochondrial quality control pathways.
In this study, researchers developed a green system to synthesize gold nanoparticles using sage leaf extract and chitosan. These nanoparticles showed effective inhibition of multidrug-resistant bacterial strains and potential for treating cancer at lower dosages than traditional drugs.
In this study, the effects of sage oil on carp were investigated. Sage oil did not affect growth, but increased antioxidant activity and improved gut health. It also increased fertility and disease resistance against A. hydrophila infection. Use of sage oil is recommended in carp farming.
These plants have been traditionally used for preventing and treating diseases like diabetes. They may contain beneficial compounds that could be useful for developing new treatments in the lab.
A study investigated the properties of three essential oils, finding differences in compounds, strong antioxidant activity in one, and impressive antifungal activity in another. Computational methods were used to examine compound-protein interactions.
Various plant extracts were examined for their ability to reduce oxidative stress in brain cells. Elderberry, Queen Garnet plum, and clove showed neuroprotective effects, while elderberry also demonstrated treatment effects. Further research is needed to explore their potential as therapies for oxidative stress-related disorders.
This study characterizes and explores the antioxidant and antimicrobial properties of essential oils from two plants in the Middle Atlas region of Morocco. The oils showed high antioxidant activity, and exhibited bactericidal effects against certain microorganisms. The findings offer insights for potential therapeutic development.
Scientists developed two spectrofluorimetric probes using ecologically synthesized copper oxide nanoparticles and a copper chelate complex to detect the anticancer drug Dabrafenib. The probes showed linear concentration ranges and low detection limits. Excipients and other substances had no effect on the detection.
Researchers studied the effects of Salvia officinalis (SAGE) on obesity and type 2 diabetes. SAGE showed potential as an anti-diabetic and anti-obesity agent in rats.
This study found that fortifying fermented camel milk with sage or mint leaves powder improves glucose and insulin levels, lipid profile, and liver and kidney functions in diabetic rats. Using sage and mint leaves powder with fermented camel milk can create functional food products with anti-diabetic activity.
A study was conducted to investigate the effectiveness of various extracts from three medicinal plants (A, B, and C) against pathogenic bacteria. The methanol extract from plant A exhibited the highest antibacterial efficacy against all tested bacteria, including multidrug-resistant strains. Additionally, a combination of plant A and a certain antibiotic showed promising results. Furthermore, plant A showed potential anticancer activity against colon cancer cells. Analysis confirmed the presence of bioactive components in the methanol extract. Molecular docking suggested that these components could inhibit the tested substances, offering potential applications in the treatment of infections and colon cancer. Overall, the methanol extract from plant A shows promise as a natural therapy for treating infections.
Researchers evaluated the potential neuroprotective effects of rosmarinic acid (RA) in a murine model of Parkinson's disease (PD) induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). RA was found to prevent hyperlocomotion behavior in MPTP-treated animals and improve the monoaminergic system in healthy animals. RA also increased dopaminergic signaling in the parkinsonian mice, indicating potential neuroprotective properties for RA in preventing behavioral features observed in PD and improving neurotransmission in the healthy brain.
Researchers conducted a systematic search to explore natural alternatives for the treatment of Alzheimer's disease (AD), as existing FDA-approved drugs have limitations. They analyzed randomized control trials and found that herbs like Gingko Biloba, Melissa Officinalis, Salvia officinalis, Ginseng, and saffron alone or in combination with curcumin, low-fat diet, NuAD-Trail, and soy lecithin showed significant positive effects on AD. Combining natural remedies with FDA-approved drugs showed more promising results than only using FDA-approved drugs. These findings suggest that herbal remedies could be effective in treating AD.