Sambucus williamsii

Ethnobotanical Studies

Clinical Trials

The Effect of Mouthwash with Sambucus williamsii var. coreana Extract on Halitosis: A Randomised, Double-Blind, Placebo-Controlled Study.

Kim YR and Nam SH (2022).
Oral Health Prev Dent.
DOI:
10.3290/j.ohpd.b3240783
PubMed:
35866676

A randomized, placebo-controlled clinical trial evaluating of a mouthwash containing Sambucus williamsii var. coreana extract for prevention of gingivitits.

Kim YR and Nam SH (2022).
Sci Rep.
DOI:
10.1038/s41598-022-15445-7
PubMed:
35851584

Studies

Lignans from Sambucus williamsii Protect Bone Via Microbiome.

Summary

SWH lignans improve bone health, but levels too low to detect in rats. Likely works through gut microbiome. Research may lead to new osteoporosis treatments.

Review Phytochemistry
Xiao HH et al (2024).
Curr Osteoporos Rep.
DOI:
10.1007/s11914-024-00883-1
PubMed:
39235563

Mechanism of action of Sambucus williamsii Hance var. miquelii in the treatment of osteoporosis analyzed by UHPLC-HRMS/MS combined network pharmacology and experimental validation.

Arthritis
Mu L et al (2024).
Fitoterapia.
DOI:
10.1016/j.fitote.2024.106003
PubMed:
38729247

Chemical characterisation of essential oil from Sambucus williamsii Hance leaves and its hepatoprotective effects.

Summary

Essential oil from Hance leaves protects liver from injury by reducing enzymes indicating liver damage, inhibiting oxidative stress and inflammation, and modulating TLR4/NF-κB pathways. Potential treatment for liver injuries.

Phytochemistry
Meng X et al (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2327637
PubMed:
38567651

Sambucus williamsii Hance: A comprehensive review of traditional uses, processing specifications, botany, phytochemistry, pharmacology, toxicology, and pharmacokinetics.

Summary

S. williamsii has medicinal properties and potential for development in traditional Chinese medicine. This paper provides a comprehensive review for future research and practical use.

Review Phytochemistry
Lei X et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.117940
PubMed:
38401662

Assessing the suitability and dynamics of three medicinal Sambucus species in China under current and future climate scenarios.

Luo W et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1194444
PubMed:
37929169

Traditional Chinese Medicine in Osteoporosis Intervention and the Related Regulatory Mechanism of Gut Microbiome.

Summary

TCM can influence the gut microbiome to combat osteoporosis. This is because the gut microbiome affects inflammation, hormone levels, nutrient absorption, and bone mass. TCM herbs can regulate the gut microbiome and indirectly impact bone health. Puerarin specifically improves intestinal health and reduces inflammation caused by estrogen deficiency.

ArthritisGastroenterology
Li K et al (2023).
Am J Chin Med.
DOI:
10.1142/S0192415X23500866
PubMed:
37884447

Comparative chloroplast genome analysis of Sambucus L. (Viburnaceae): inference for phylogenetic relationships among the closely related Sambucus adnata Wall. ex DC Sambucus javanica Blume.

Genetics
Waswa EN et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1179510
PubMed:
37396648

Identification, characterization and chemical management of Alternaria alternata causing blackcurrant leaf spot in China.

Genetics
Xu C et al (2023).
J Appl Microbiol.
DOI:
10.1093/jambio/lxad025
PubMed:
36764663

Anti-Caries Effect of a Mouthwash Containing Sambucus williamsii var. coreana Extract: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Kim YR and Nam SH (2022).
Antibiotics (Basel).
DOI:
10.3390/antibiotics11040488
PubMed:
35453239

Phytochemicals and potential health effects of Sambucus williamsii Hance (Jiegumu).

Review
Xiao HH et al (2016).
Chin Med.
DOI:
10.1186/s13020-016-0106-9
PubMed:
27478495

Root bark of Sambucus Williamsii Hance promotes rat femoral fracture healing by the BMP-2/Runx2 signaling pathway.

Yang B et al (2016).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2016.05.017
PubMed:
27178636

Sambucus Williamsii Hance Promotes MC3T3-E1 Cells Proliferation and Differentiation via BMP-2/Smad/p38/JNK/Runx2 Signaling Pathway.

Yang B et al (2015).
Phytother Res.
DOI:
10.1002/ptr.5482
PubMed:
26455827

Sambucus williamsii induced embryonic stem cells differentiated into neurons.

Liu SP et al (2015).
Biomedicine (Taipei).
DOI:
10.7603/s40681-015-0003-z
PubMed:
25705583