Saposhnikovia divaricata

Ethnobotanical Studies

Studies

Genomic, transcriptomic, and metabolomic analyses provide insights into the evolution and development of a medicinal plant Saposhnikovia divaricata (Apiaceae).

Wang ZH et al (2024).
Hortic Res.
DOI:
10.1093/hr/uhae105
PubMed:
38883332

Determining Antiradical Capacity of Medicinal Plant Extract Individual Constituents Using Post-Column Reaction Method.

Przybył JL et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25105461
PubMed:
38791498

Chemical constituents from the Saposhnikovia divaricata and their antiproliferative activity.

Summary

Scientists isolated and identified new compounds from plant extracts, testing them for anti-cancer activity. Results show compounds (-) may not be effective for cancer treatment.

Cancer
Sun Y et al (2024).
Z Naturforsch C J Biosci.
DOI:
10.1515/znc-2024-0009
PubMed:
38780504

Knowledge mapping of links between dendritic cells and allergic diseases: A bibliometric analysis (2004-2023).

Meng X et al (2024).
Heliyon.
DOI:
10.1016/j.heliyon.2024.e30315
PubMed:
38765036

A new 3,4-dihydroisocoumarin and an antiinflammatory coumarin from the roots of Saposhnikovia divaricata (Turcz.) Schischk.

Sun Y et al (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2334317
PubMed:
38563116

Multi-omics reveals that 5-O-methylvisammioside prevention acute liver injury in mice by regulating the TNF/MAPK/NF-κB/arachidonic acid pathway.

Immunology
Zhang T et al (2024).
Phytomedicine.
DOI:
10.1016/j.phymed.2024.155550
PubMed:
38522313

Polyacetylenes from Saposhnikovia divaricata and their anticancer activity.

Summary

Researchers isolated 9 polyacetylenes from Saposhnikovia divaricata roots, including 5 new compounds, and determined their structures. Compound 9 showed moderate cytotoxicity against HEPG2 cancer cells.

Cancer
Sun Y et al (2024).
Fitoterapia.
DOI:
10.1016/j.fitote.2024.105876
PubMed:
38431027

Comprehensive study on genetic and chemical diversity of Asian medicinal plants, aimed at sustainable use and standardization of traditional crude drugs.

Review
Komatsu K et al (2023).
J Nat Med.
DOI:
10.1007/s11418-023-01770-2
PubMed:
38133706

Assembly and comparative analysis of the first complete mitochondrial genome of a traditional Chinese medicine Angelica biserrata (Shan et Yuan) Yuan et Shan.

Genetics
Wang L et al (2023).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.128571
PubMed:
38052286

Evaluation and control of Fusarium acuminatum causing leaf spot in Saposhnikovia divaricata in Northeast China.

Jiang Y et al (2023).
Plant Dis.
DOI:
10.1094/PDIS-09-23-1777-SR
PubMed:
38037202

YuPingFeng (YPF) upregulates caveolin-1 (CAV1) to alleviate pulmonary fibrosis through the TGF-β1/Smad2 pathway.

Chen X et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117357
PubMed:
37898439

[Effects of chemical fertilizer reduction and organic fertilizer substitution on yield and quality of Saposhnikovia divaricata].

Li Q et al (2023).
Zhongguo Zhong Yao Za Zhi.
DOI:
10.19540/j.cnki.cjcmm.20230414.103
PubMed:
37802803

Effects of Yu-Ping-Feng polysaccharides on animal growth performance and immune function: a review.

Review
Chu H et al (2023).
Front Vet Sci.
DOI:
10.3389/fvets.2023.1260208
PubMed:
37799408

Sodium nitroprusside improved the quality of Radix Saposhnikoviae through constructed physiological response under ecological stress.

Song XW et al (2023).
Sci Rep.
DOI:
10.1038/s41598-023-43153-3
PubMed:
37740027

Advances in Phytochemistry and Modern Pharmacology of Saposhnikovia Divaricata (Turcz.) Schischk.

Summary

Scientists reviewed studies on the chemical composition and pharmacological activity of S. divaricata, a medicinal herb. It has been found to have antipyretic, analgesic, anti-inflammatory, antioxidant, anti-tumor, and anticoagulant effects. They propose investigating the synergistic effects and prioritizing structure-effect relationships in future research.

Review Phytochemistry
Gao JW et al (2023).
Chin J Integr Med.
DOI:
10.1007/s11655-023-3746-5
PubMed:
37733271

Tong-Xie-Yao-Fang promotes dendritic cells maturation and retards tumor growth in colorectal cancer mice with chronic restraint stress.

Summary

Researchers investigated the effect of Tong-Xie-Yao-Fang (TXYF), a traditional Chinese medicine formula, on colorectal cancer (CRC) accompanied by psychological stress. TXYF improved depression and reduced intestinal symptoms, suggesting its potential as an intervention for CRC patients with psychological stress.

CancerGastroenterology
Jiang Y et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117069
PubMed:
37619860

Effects of different drying methods on the contents of active ingredients of Saposhnikovia divaricata (Turcz.) Schischk and optimization of the drying process by response surface methodology.

Sun X et al (2023).
Phytochem Anal.
DOI:
10.1002/pca.3269
PubMed:
37501406

Effects and potential mechanisms of Saposhnikovia divaricata (Turcz.) Schischk. On type I allergy and pseudoallergic reactions in vitro and in vivo.

Liang X et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116942
PubMed:
37487961

Research on the improvement effect of Saposhnikovia divaricata (Trucz.) Schischk on rheumatoid arthritis based on the "component-target-pathway" association.

Arthritis
Liu CL et al (2023).
Anal Biochem.
DOI:
10.1016/j.ab.2023.115184
PubMed:
37285946

Comparative transcriptome analysis of Saposhnikovia divaricata to reveal drought and rehydration adaption strategies.

Genetics
Su Y et al (2023).
Mol Biol Rep.
DOI:
10.1007/s11033-023-08305-8
PubMed:
36781610

Molecular Mechanism of the Saposhnikovia divaricata-Angelica dahurica Herb Pair in Migraine Therapy Based on Network Pharmacology and Molecular Docking.

Wu F et al (2022).
Evid Based Complement Alternat Med.
DOI:
10.1155/2022/1994575
PubMed:
36479181

Traditional Chinese medicine Tongxie Yaofang treating irritable bowel syndrome with diarrhea and type 2 diabetes mellitus in rats with liver-depression and spleen-deficiency: A preliminary study.

Summary

Researchers investigated the Chinese medicine Tongxie Yaofang (TXYF) in treating inflammation in rats with irritable bowel syndrome (IBS) and type 2 diabetes (T2DM). Rat models were created and given TXYF treatment, and major inflammatory factors and intestinal permeability proteins were measured through H&E staining, ELISA, and immunohistochemistry. Results show that TXYF treatment reduced inflammatory reactions and improved disease states in rats with D-IBS and T2DM. The study suggests potential benefits of TXYF in treating these conditions.

DiabetesNeuroscience
Xu W et al (2022).
Front Nutr.
DOI:
10.3389/fnut.2022.968930
PubMed:
36438735

Ecological roles of secondary metabolites of Saposhnikovia divaricata in adaptation to drought stress.

Cao S et al (2022).
PeerJ.
DOI:
10.7717/peerj.14336
PubMed:
36353606

Prim-O-glucosycimifugin attenuates liver injury in septic mice by inhibiting NLRP3 inflammasome/caspase-1 signaling cascades in macrophages.

Immunology
Liu LL et al (2022).
Phytomedicine.
DOI:
10.1016/j.phymed.2022.154427
PubMed:
36088791

Network pharmacology-based analysis of the mechanism of Saposhnikovia divaricata for the treatment of type I allergy.

Li X et al (2022).
Pharm Biol.
DOI:
10.1080/13880209.2022.2086583
PubMed:
35760567

The Chloroplast Genome of Wild Saposhnikovia divaricata: Genomic Features, Comparative Analysis, and Phylogenetic Relationships.

Genetics
Yi S et al (2022).
Genes (Basel).
DOI:
10.3390/genes13050931
PubMed:
35627316

Cimifugin Ameliorates Lipotoxicity-Induced Hepatocyte Damage and Steatosis through TLR4/p38 MAPK- and SIRT1-Involved Pathways.

Immunology
Yang W et al (2022).
Oxid Med Cell Longev.
DOI:
10.1155/2022/4557532
PubMed:
35355867

Three new coumarins from Saposhnikovia divaricata and their porcine epidemic diarrhea virus (PEDV) inhibitory activity.

Yang JL et al (2015).
Tetrahedron.
DOI:
10.1016/j.tet.2015.04.092
PubMed:
32287428

Analgesic components of saposhnikovia root (Saposhnikovia divaricata).

Pain
Okuyama E et al (2001).
Chem Pharm Bull (Tokyo).
PubMed:
11217101