Sarcandra glabra

Ethnobotanical Studies

Studies

Sarcanoids A and B, two new lindenane-type sesquiterpenoid dimers from the aerial parts of Sarcandra glabra.

Liu J et al (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2364919
PubMed:
38884117

Polysaccharide extracted from Sarcandra glabra residue attenuate cognitive impairment by regulating gut microbiota in diabetic mice.

Summary

SERP from Sarcandra glabra improves cognitive function in diabetic encephalopathy by regulating gut microbiota, lipid metabolism, and butyric acid levels. Promising treatment option targeting "microbiota-gut-brain axis".

DiabetesGastroenterologyNeuroscience
Ye M et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.132121
PubMed:
38719002

Corrigendum: Combination effect of three main constituents from Sarcandra glabra inhibits oxidative stress in the mice following acute lung injury: a role of MAPK-NF-κB pathway.

Immunology
Liu C et al (2024).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1335005
PubMed:
38576894

Sarcandra glabra (Thunb.) Nakai alleviates DSS-induced ulcerative colitis by promoting restitution, restoring barrier function, and modulating IL-17/Notch1/FoxP3 pathway in intestinal cells.

Summary

Researchers studied the effects of Sarcandra glabra on ulcerative colitis. Its traditional use in treating digestive diseases suggests potential therapeutic benefits for UC. Important for developing new treatments.

GastroenterologyImmunology
Zhang S et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118131
PubMed:
38565408

Trisarcglaboids A and B, two cytotoxic lindenane sesquiterpenoid trimers with a unique polymerization mode isolated from Sarcandra glabra.

Zhang D et al (2024).
Bioorg Chem.
DOI:
10.1016/j.bioorg.2024.107259
PubMed:
38460335

[Tissue specific distribution of terpenoid biosynthesis in Sarcandra glabra based on transcriptome and metabolome analysis].

Genetics
Wu D et al (2024).
Sheng Wu Gong Cheng Xue Bao.
DOI:
10.13345/j.cjb.230371
PubMed:
38369840

Caffeic acid 3,4-dihydroxyphenethyl ester prevents colorectal cancer through inhibition of multiple cancer-promoting signal pathways in 1,2-Dimethylhydrazine/dextran sodium sulphate mouse model.

Summary

Researchers studied the molecule CADPE and its potential to prevent colorectal cancer in a mouse model induced by the use of DMH and DSS. Results could contribute to future cancer prevention strategies.

CancerGastroenterology
Tao J et al (2024).
J Tradit Chin Med.
DOI:
10.19852/j.cnki.jtcm.20231204.001
PubMed:
38213241

A comprehensive review on the chemical constituents, sesquiterpenoid biosynthesis and biological activities of Sarcandra glabra.

Review
Chu JN, Krishnan P and Lim KH (2023).
Nat Prod Bioprospect.
DOI:
10.1007/s13659-023-00418-8
PubMed:
38010490

Integrated transcriptome and proteome analyses unravel a series of early defence responses in Sarcandra glabra against Colletotrichum gloeosporioides.

Genetics
Jiang N et al (2023).
Funct Plant Biol.
DOI:
10.1071/FP23084
PubMed:
37814360

Anti-Inflammatory Lindenane Sesquiterpenoid Dimers from the Roots of Sarcandra glabra.

Summary

Researchers discovered new compounds from the roots of a plant and determined their structures using various techniques. These compounds showed promising anti-inflammatory and anti-proliferation properties in the lab.

Immunology
Sun Y et al (2023).
J Agric Food Chem.
DOI:
10.1021/acs.jafc.3c02926
PubMed:
37704568

Synergistic effects of vegetation and microorganisms on enhancing of biodegradation of landfill gas.

Review
Shangjie C et al (2023).
Environ Res.
DOI:
10.1016/j.envres.2023.115804
PubMed:
37003556

In vitro antifungal activity of lasiodiplodin, isolated from endophytic fungus Lasiodiplodia pseudotheobromae J-10 associated with Sarcandra glabra and optimization of culture conditions for lasiodiplodin production.

Antimicrobial
Luo H et al (2023).
Arch Microbiol.
DOI:
10.1007/s00203-023-03440-z
PubMed:
36964826

Sarglamides A-E, Indolidinoid-Monoterpenoid Hybrids with Anti-neuroinflammatory Activity from a Sarcandra Species.

Summary

Researchers isolated Sarglamides A-E from a plant and found that compounds - and - have unique structures. They proposed possible pathways for their creation and found that compounds - can reduce inflammation.

ImmunologyNeuroscience
Zhou B et al (2023).
Org Lett.
DOI:
10.1021/acs.orglett.3c00196
PubMed:
36825855

Natural and Pseudonatural Lindenane Heterodimers from Sarcandra glabra by Molecular Networking.

Cui Z et al (2022).
Org Lett.
DOI:
10.1021/acs.orglett.2c03769
PubMed:
36469558

In-Forest Planting of High-Value Herb Sarcandra glabra Enhances Soil Carbon Storage without Affecting the Diversity of the Arbuscular Mycorrhiza Fungal Community and Composition of Cunninghamia lanceolata.

Zhou H et al (2022).
Microorganisms.
DOI:
10.3390/microorganisms10091844
PubMed:
36144446

Coumarins from Sarcandra glabra (Thunb.) Nakai and Acetylcholinesterase Inhibiting Activity.

Summary

Researchers isolated nine coumarins from the Sarcandra glabra plant, including a newly discovered pair of enantiomers. They tested all the compounds for acetylcholinesterase inhibiting activity and found that compound 3 showed the most significant effect with an IC value of 1.982±0.003 μM. The study confirms the potential therapeutic properties of coumarins and its ability to target Alzheimer's disease.

Neuroscience
Du NN et al (2022).
Chem Biodivers.
DOI:
10.1002/cbdv.202200558
PubMed:
36036517

Protective effects of isofraxidin against scopolamine-induced cognitive and memory impairments in mice involve modulation of the BDNF-CREB-ERK signaling pathway.

Summary

Isofraxidin is a molecule found in plants that are useful for brain diseases. It is extracted from plants like Sarcandra glabra, Apium graveolens, and Siberian Ginseng.

Neuroscience
Lian B et al (2022).
Metab Brain Dis.
DOI:
10.1007/s11011-022-00980-z
PubMed:
35921056

Assessment of the Potential of Sarcandra glabra (Thunb.) Nakai. in Treating Ethanol-Induced Gastric Ulcer in Rats Based on Metabolomics and Network Analysis.

Gastroenterology
Li C et al (2022).
Front Pharmacol.
DOI:
10.3389/fphar.2022.810344
PubMed:
35903344

Anti-inflammatory effects of a SERP 30 polysaccharide from the residue of Sarcandra glabra against lipopolysaccharide-induced acute respiratory distress syndrome in mice.

Immunology
Feng Q et al (2022).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2022.115262
PubMed:
35398243

(±)-Sarcanan A, a pair of new enantiomeric dihydrobenzofuran neolignans from the aerial parts of Sarcandra glabra.

Liu J et al (2023).
Nat Prod Res.
DOI:
10.1080/14786419.2022.2050229
PubMed:
35285363

[Research progress on chemical constituents and biological activities of Sarcandra glabra].

Review
Chen FY, Chen ZC and Luo YM (2022).
Zhongguo Zhong Yao Za Zhi.
DOI:
10.19540/j.cnki.cjcmm.20211012.201
PubMed:
35285185

Sarcandra glabra combined with lycopene protect rats from lipopolysaccharide induced acute lung injury via reducing inflammatory response.

Immunology
Liu TY and Chen SB (2016).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2016.09.009
PubMed:
27631138