Saururus chinensis

Ethnobotanical Studies

Studies

Saururus chinensis (Lour.) Baill. extract promotes skeletal muscle cell differentiation by positively regulating mitochondrial biogenesis and AKT/mTOR signaling in vitro.

Eun SY et al (2024).
Mol Med Rep.
DOI:
10.3892/mmr.2024.13250
PubMed:
38785149

The synchronized feature of Saururus chinensis and gut microbiota against T2DM, NAFLD, obesity and hypertension via integrated pharmacology.

Summary

Study uncovers therapeutic potential of gut microbiota and plant compounds for metabolic disorders. Key genes and bioactive compounds identified could lead to novel treatments for type 2 diabetes, NAFLD, obesity, and hypertension.

CardiologyGastroenterologyObesity
Oh KK et al (2024).
Artif Cells Nanomed Biotechnol.
DOI:
10.1080/21691401.2024.2350475
PubMed:
38733373

Antiviral Mechanisms of Saucerneol from Saururus chinensis against Enterovirus A71, Coxsackievirus A16, and Coxsackievirus B3: Role of Mitochondrial ROS and the STING/TKB-1/IRF3 Pathway.

Summary

Compound saucerneol from [unspecified source] is a promising antiviral against Enterovirus A71, coxsackievirus A16, and coxsackievirus B3. It suppresses virus replication, relieves pancreatitis, and activates the STING/TBK-1/IRF3 pathway. Further research is needed on safety and effectiveness for antiviral strategies.

Antimicrobial
Song JH et al (2023).
Viruses.
DOI:
10.3390/v16010016
PubMed:
38275951

A Mixture of Artemisia argyi and Saururus chinensis Improves PM(2.5)-Induced Cognitive Dysfunction by Regulating Oxidative Stress and Inflammatory Response in the Lung and Brain.

Summary

This study investigated the impact of a mixture of plant compounds (AASC) on cognitive dysfunction in mice exposed to fine particulate matter (PM) smaller than 2.5 µm. The results confirmed cognitive dysfunction in the PM group, which resulted in oxidative stress, inflammation, and mitochondrial dysfunction. AASC suppressed brain and lung oxidative stress and inflammation, which reduced brain Alzheimer's beta (Aβ) expression. This suggests that consuming plants with antioxidant and anti-inflammatory activity may prevent cognitive decline caused by PM exposure.

ImmunologyNeuroscience
Kang JY et al (2023).
Plants (Basel).
DOI:
10.3390/plants12061230
PubMed:
36986919

Machilin D Promotes Apoptosis and Autophagy, and Inhibits Necroptosis in Human Oral Squamous Cell Carcinoma Cells.

Yun HM et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24054576
PubMed:
36902006

The Saururus chinensis genome provides insights into the evolution of pollination strategies and herbaceousness in magnoliids.

Genetics
Xue JY et al (2023).
Plant J.
DOI:
10.1111/tpj.16097
PubMed:
36602036

The underlying hepatoprotective mechanism of PKC#963 in alcohol or carbon tetrachloride induced liver injury via inhibition of iNOS, COX-2, and p-STAT3 and enhancement of SOD and catalase.

Immunology
Kim DS et al (2023).
Phytother Res.
DOI:
10.1002/ptr.7630
PubMed:
36151597

Inhibitory Effects of Saururus chinensis Extract on Receptor for Advanced Glycation End-Products-Dependent Inflammation and Diabetes-Induced Dysregulation of Vasodilation.

Immunology
Hayashi K et al (2022).
Int J Mol Sci.
DOI:
10.3390/ijms23105757
PubMed:
35628567

Studies on the Antiliver Injury of Effective Parts from Saururus chinensis by Rats and Mice Model In Vivo.

Wang C et al (2022).
Evid Based Complement Alternat Med.
DOI:
10.1155/2022/7821724
PubMed:
35518346

Saucerneol attenuates nasopharyngeal carcinoma cells proliferation and metastasis through selectively targeting Grp94.

Cancer
Cheng Y et al (2022).
Phytomedicine.
DOI:
10.1016/j.phymed.2022.154133
PubMed:
35504052

A Traditional Chinese Medicine for the Treatment of Endometrial Hyperplasia via Regulating the HPO Axis in Rats.

Lv B et al (2022).
Evid Based Complement Alternat Med.
DOI:
10.1155/2022/5200608
PubMed:
35154346

Evolution of NLR Resistance Genes in Magnoliids: Dramatic Expansions of CNLs and Multiple Losses of TNLs.

Genetics
Wu JY, Xue JY and Van de Peer Y (2021).
Front Plant Sci.
DOI:
10.3389/fpls.2021.777157
PubMed:
34992620

Comparative pharmacokinetic study of six lignans in normal and diabetic rats after oral administration of Saururus chinensis extract by LC-MS/MS.

DiabetesPhytochemistry
Chen H et al (2022).
Biomed Chromatogr.
DOI:
10.1002/bmc.5253
PubMed:
34596250

Sauchinone inhibits hypoxia-induced invasion and epithelial-mesenchymal transition in osteosarcoma cells via inactivation of the sonic hedgehog pathway.

Zhou D and He L (2022).
J Recept Signal Transduct Res.
DOI:
10.1080/10799893.2021.1881556
PubMed:
33563062

Matrix Solid-Phase Dispersion Combined with HPLC-DAD for Simultaneous Determination of Nine Lignans in Saururus chinensis.

Phytochemistry
Chen H et al (2019).
J Chromatogr Sci.
DOI:
10.1093/chromsci/bmy090
PubMed:
30272133

Saururus chinensis Baill inhibits proliferation and invasion of human renal cell carcinoma cells through inhibition of inhibitor of apoptosis protein.

Park YH et al (2016).
Chin J Integr Med.
PubMed:
27909997