Schinus molle

Common Names: American pepper, false pepper, molle del Peru, pepper tree, peppertree, Peruvian peppertree

Ethnobotanical Studies

Studies

In Vitro Antiprotozoal Activity of Schinus molle Extract, Partitions, and Fractions against Trypanosoma cruzi.

Rodríguez-Garza NE et al (2024).
Plants (Basel).
DOI:
10.3390/plants13162177
PubMed:
39204613

Phytochemical characterization and nutritional value of vegetable oils from ripe berries of Schinus terebinthifolia raddi and Schinus molle L., through extraction methods.

Phytochemistry
Belhoussaine O et al (2024).
Food Chem X.
DOI:
10.1016/j.fochx.2024.101580
PubMed:
39027685

Acute toxicity and genotoxicity of Schinus molle L. aqueous extract/ethanol-soluble fraction in rats.

Machado CD et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118499
PubMed:
38936645

Antileishmanial and Antifungal Activities of Volatile Oils from Cinnamomum cassia Bark and Schinus molle Leaves.

Summary

Researchers studied the antiparasitic and antifungal properties of Schinus molle and Cinnamomum cassia essential oils, as well as their blends. Results show promising activity against Leishmania and Candida, indicating potential for new treatments.

Antimicrobial
da Silva ASR et al (2024).
Chem Biodivers.
DOI:
10.1002/cbdv.202401076
PubMed:
38899851

Sustainable strategy for rehabilitating phosphate mining sites and valorisation of phosphate industry by-products and sludge using pistachio tree (Pistacia atlantica), false pepper (Schinus molle), and eucalyptus (Eucalyptus globulus) trees.

Guéablé YKD et al (2024).
Sci Total Environ.
DOI:
10.1016/j.scitotenv.2024.173485
PubMed:
38797404

The first peoples of the Atacama Desert lived among the trees: A 11,600- to 11,200-year-old grove and congregation site.

Ugalde PC et al (2024).
Proc Natl Acad Sci U S A.
DOI:
10.1073/pnas.2320506121
PubMed:
38648488

Evaluation of hepatoprotective and antidiarrheal activities of the hydromethanol crude extract and solvent fractions of Schinus molle L. (Anacardiaceae) leaf and fruit in mice.

Belayneh YM, Mengistu G and Hailay K (2024).
Metabol Open.
DOI:
10.1016/j.metop.2024.100272
PubMed:
38455232

Synthesis and toxicological study of chitosan-pirul (Schinus molle L.) essential oil nanoparticles on Aspergillus flavus.

Phytochemistry
Plascencia-Jatomea M et al (2024).
Arch Microbiol.
DOI:
10.1007/s00203-024-03859-y
PubMed:
38430254

Influence of socio-demographic factors on medicinal plant knowledge among three selected ethnic groups in south-central Ethiopia.

Tamene S et al (2024).
J Ethnobiol Ethnomed.
DOI:
10.1186/s13002-024-00672-1
PubMed:
38419117

Prediction of Novel Natural Small Molecules From Schinus molle as an Inhibitor of PI3K Protein Target in Cancer Cells Using In Silico Screening.

Summary

Phytochemicals from plants were screened for their potential as inhibitors of PI3K, a key target in cancer therapy. Beta-spathulene and kaempferol showed promising affinity for PI3K, but further experimental studies are needed for validation.

Cancer
Kumar U et al (2023).
Cureus.
DOI:
10.7759/cureus.50863
PubMed:
38259388

Assessment of Phenolic Composition, Antioxidant Potential, Antimicrobial Properties, and Antidiabetic Activity in Extracts Obtained from Schinus molle L. Leaves and Fruits.

Summary

This study investigates the health benefits (antioxidant, antimicrobial, antidiabetic) of a specific plant grown in Turkey. Important for finding new natural remedies or improving existing treatments in various fields.

AntimicrobialDiabetesImmunologyPhytochemistry
İlgün S et al (2023).
Front Biosci (Landmark Ed).
DOI:
10.31083/j.fbl2812353
PubMed:
38179764

Chemical composition and allelopathic potential of Schinus molle L. (Anacardiaceae) essential oils against common weeds of wheat crop.

Lalia A et al (2023).
Nat Prod Res.
DOI:
10.1080/14786419.2023.2287174
PubMed:
38006326

Development of an electrochemical sensor using carbon nanotubes and hydrophobic natural deep eutectic solvents for the detection of α-glucosidase activity in extracts of autochthonous medicinal plants.

Aschemacher NA et al (2023).
Talanta.
DOI:
10.1016/j.talanta.2023.125313
PubMed:
37864855

Chemical composition and anti-Xanthomonas citri activities of essential oils from Schinus molle L. fresh and dry leaves and of its major constituent spathulenol.

da Silva IRR et al (2023).
Nat Prod Res.
DOI:
10.1080/14786419.2023.2249584
PubMed:
37606013

In-silico and in-vitro assessments of some fabaceae, rhamnaceae, apocynaceae, and anacardiaceae species against Mycobacterium tuberculosis H37Rv and triple-negative breast cancer cells.

Summary

Medicinal plants in South Africa's Limpopo province have long been used to treat diseases like tuberculosis and cancer. In this study, researchers evaluated the antimycobacterial and cytotoxic activity of five plants, including Rauvolfia caffra and Schinus molle, against various strains of bacteria and breast cancer cells. The extracts from R. caffra and S. molle showed promising results, particularly against M. tuberculosis. Further analysis identified a compound called norajmaline as a potential lead for antimycobacterial treatment. Additionally, the extracts from Senna petersiana, Ziziphus mucronate, R. caffra, and S. molle demonstrated potential for treating triple-negative breast cancer. Further research is needed to validate these findings and explore chemical modifications for enhanced effectiveness.

Cancer
Nyambo K et al (2023).
BMC Complement Med Ther.
DOI:
10.1186/s12906-023-04041-5
PubMed:
37393246

Chemical and cytotoxicity profiles of 11 pink pepper (Schinus spp.) samples via non-targeted hyphenated high-performance thin-layer chromatography.

Phytochemistry
Mügge FLB and Morlock GE (2023).
Metabolomics.
DOI:
10.1007/s11306-023-02008-8
PubMed:
37130976

Fumigant toxicity of four essential oils against the carob moth Ectomyelois ceratoniae Zeller and the Mediterranean flour moth Ephestia kuehniella.

Phytochemistry
Chaaban SB et al (2022).
Int J Environ Health Res.
DOI:
10.1080/09603123.2022.2152431
PubMed:
36463575

First Evidence of Gastroprotection by Schinus molle: Roles of Nitric Oxide, Prostaglandins, and Sulfhydryls Groups in Its Mechanism of Action.

Sánchez-Mendoza ME et al (2022).
Molecules.
DOI:
10.3390/molecules27217321
PubMed:
36364146

Entomopathogenic fungi and Schinus molle essential oil: The combination of two eco-friendly agents against Aedes aegypti larvae.

Phytochemistry
de Oliveira Barbosa Bitencourt R et al (2022).
J Invertebr Pathol.
DOI:
10.1016/j.jip.2022.107827
PubMed:
36108793

In vivo evaluation and molecular docking studies of Schinus molle L. fruit extract protective effect against isoproterenol-induced infarction in rats.

Feriani A et al (2022).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-022-21422-4
PubMed:
35729379

Chemical Composition, Antioxidant, Insecticidal Activity, and Comparative Analysis of Essential Oils of Leaves and Fruits of Schinus molle and Schinus terebinthifolius.

Phytochemistry
Belhoussaine O et al (2022).
Evid Based Complement Alternat Med.
DOI:
10.1155/2022/4288890
PubMed:
35677362

GC-MS Profile, Antioxidant Activity, and In Silico Study of the Essential Oil from Schinus molle L. Leaves in the Presence of Mosquito Juvenile Hormone-Binding Protein (mJHBP) from Aedes aegypti.

EndocrinologyPhytochemistry
Herrera-Calderon O et al (2022).
Biomed Res Int.
DOI:
10.1155/2022/5601531
PubMed:
35615009

Eugenia uniflora, Melaleuca armillaris, and Schinus molle essential oils to manage larvae of the filarial vector Culex quinquefasciatus (Diptera: Culicidae).

Phytochemistry
de Castro Oliveira JA et al (2022).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-021-18024-x
PubMed:
35043299

HPLC-ESI-QTOF-MS/MS profiling and therapeutic effects of Schinus terebinthifolius and Schinus molle fruits: investigation of their antioxidant, antidiabetic, anti-inflammatory and antinociceptive properties.

DiabetesImmunologyPain
Feriani A et al (2021).
Inflammopharmacology.
DOI:
10.1007/s10787-021-00791-1
PubMed:
33635473

Antimalarial Activity of Seed Extracts of Schinus molle Against Plasmodium berghei in Mice.

Mekuria AB et al (2021).
J Evid Based Integr Med.
DOI:
10.1177/2515690X20984287
PubMed:
33593094