Scleromitrion diffusum

Ethnobotanical Studies

Gelao ethnic minority, North Guizhou, China

Uses: Snake bite

DOI:: 10.3389/fphar.2023.1217599
PubMed:: 37719846

Yi people, Mile, Yunnan, China

Uses: Dysentery, hepatitis, pharyngitis

DOI:: 10.1186/s13002-024-00656-1
PubMed:: 38395900

Gaoligongshan area, Western Yunnan, Southwest China

Uses: Anti-inflammatory, laryngalgia

DOI:: 10.1186/s13002-023-00638-9
PubMed:: 38225656

Studies

Scutellaria barbata D.Don and Scleromitrion diffusum (Willd.) R.J.Wang inhibits the progression of triple negative breast cancer though the activation inhibition of NF-κB triggered by CAFs-derived IL6.

Summary

Researchers studied the herb pair Scutellaria barbata and Scleromitrion diffusum for their anti-tumor effects on triple-negative breast cancer. Understanding their molecular mechanisms can lead to new treatment options.

Cancer Immunology

Pan Y et al (2024).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2024.118656
PubMed:: 39121924

Exploring the mechanism of Scleromitrion diffusum (Willd.) in treating lung cancer based on network pharmacology and experimental validation.

Summary

SDW components target 88 genes in lung cancer treatment, inhibiting cell proliferation via P I3K/Akt and MEK/ERK pathways. SDW may regulate apoptosis and proliferation in lung cancer therapy. Valuable insights into molecular mechanisms provided through network pharmacology, molecular docking, and experimental validation.

Cancer

Huang S et al (2024).; Nat Prod Res.
DOI:: 10.1080/14786419.2024.2367244
PubMed:: 38885333

Comparative study of Scleromitrion diffusum and Oldenlandia corymbosa: Microscopy, TLC, HPLC, and antioxidant activity.

Immunology

Ho YL et al (2024).; Microsc Res Tech.
DOI:: 10.1002/jemt.24611
PubMed:: 38808861

The anti-inflammatory effects of Hedyotis diffusa Willd on SLE with STAT3 as a key target.

Immunology

Xu L et al (2022).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2022.115597
PubMed:: 35940466

Effect of Chinese Herbal Medicine Therapy on Overall and Cancer Related Mortality in Patients With Advanced Nasopharyngeal Carcinoma in Taiwan.

Cancer

Wang CY et al (2021).; Front Pharmacol.
DOI:: 10.3389/fphar.2020.607413
PubMed:: 33708119

Antitumor Effects and the Compatibility Mechanisms of Herb Pair Scleromitrion diffusum (Willd.) R. J. Wang-Sculellaria barbata D. Don.

Cancer

Lu L et al (2020).; Front Pharmacol.
DOI:: 10.3389/fphar.2020.00292
PubMed:: 32265701