Scutellaria lateriflora

Common Names: blue skullcap

Ethnobotanical Studies

Clinical Trials

Efficacy and Tolerability of a Scutellaria lateriflora L. and Cistus × incanus L.-Based Chewing Gum on the Symptoms of Gingivitis: A Monocentric, Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Di Minno A et al (2024).
Nutrients.
DOI:
10.3390/nu16060862
PubMed:
38542772

American Skullcap (Scutellaria lateriflora): a randomised, double-blind placebo-controlled crossover study of its effects on mood in healthy volunteers.

Brock C et al (2014).
Phytother Res.
DOI:
10.1002/ptr.5044
PubMed:
23878109

Studies

Baicalein inhibits IL-1β-induced extracellular matrix degradation with decreased MCP-1 expression in primary rat chondrocytes.

Immunology
Cho I et al (2024).
Toxicol Res.
DOI:
10.1007/s43188-024-00225-4
PubMed:
38525128

In Vitro Assessment of Cortisol Release Inhibition, Bioaccessibility and Bioavailability of a Chemically Characterized Scutellaria lateriflora L. Hydroethanolic Extract.

Buccato DG et al (2024).
Molecules.
DOI:
10.3390/molecules29030586
PubMed:
38338331

Biotechnological strategies for controlled accumulation of flavones in hairy root culture of Scutellaria lateriflora L.

Wilczańska A et al (2023).
Sci Rep.
DOI:
10.1038/s41598-023-47757-7
PubMed:
37990031

The Influence of Microwave-Assisted Extraction on the Phenolic Compound Profile and Biological Activities of Extracts from Selected Scutellaria Species.

Phytochemistry
Oracz J et al (2023).
Molecules.
DOI:
10.3390/molecules28093877
PubMed:
37175287

In Vitro Antimicrobial and Antibiofilm Properties and Bioaccessibility after Oral Digestion of Chemically Characterized Extracts Obtained from Cistus × incanus L., Scutellaria lateriflora L., and Their Combination.

Antimicrobial
Ullah H et al (2023).
Foods.
DOI:
10.3390/foods12091826
PubMed:
37174364

Baicalin Modulates Inflammatory Response of Macrophages Activated by LPS via Calcium-CHOP Pathway.

Immunology
An HJ, Lee JY and Park W (2022).
Cells.
DOI:
10.3390/cells11193076
PubMed:
36231038

Network pharmacology-based investigation and experimental validation of the mechanism of scutellarin in the treatment of acute myeloid leukemia.

Cancer
Huang Z et al (2022).
Front Pharmacol.
DOI:
10.3389/fphar.2022.952677
PubMed:
36160389

Antioxidant Potential and Enhancement of Bioactive Metabolite Production in In Vitro Cultures of Scutellaria lateriflora L. by Biotechnological Methods.

Kwiecień I et al (2022).
Molecules.
DOI:
10.3390/molecules27031140
PubMed:
35164404

In Vitro Cultures of Some Medicinal Plant Species (Cistus × incanus, Verbena officinalis, Scutellaria lateriflora, and Scutellaria baicalensis) as a Rich Potential Source of Antioxidants-Evaluation by CUPRAC and QUENCHER-CUPRAC Assays.

Dziurka M et al (2021).
Plants (Basel).
DOI:
10.3390/plants10030454
PubMed:
33673698

Baicalin Inhibits Cell Viability, Migration and Invasion in Breast Cancer by Regulating miR-338-3p and MORC4.

Cancer
Duan X et al (2019).
Onco Targets Ther.
DOI:
10.2147/OTT.S217101
PubMed:
31908485

Do recent research studies validate the medicinal plants used in British Columbia, Canada for pet diseases and wild animals taken into temporary care?

Review
Lans C et al (2019).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2019.02.030
PubMed:
30772483

Molecular characterization of flavonoid biosynthetic genes and accumulation of baicalin, baicalein, and wogonin in plant and hairy root of Scutellaria lateriflora.

Genetics
Tuan PA et al (2018).
Saudi J Biol Sci.
DOI:
10.1016/j.sjbs.2016.08.011
PubMed:
30591781

Baicalin alleviates osteomyelitis by regulating TLR2 in the murine model.

Wu T et al (2018).
Pathog Dis.
DOI:
10.1093/femspd/ftx123
PubMed:
29253124

Baicalin inhibits the metastasis of highly aggressive breast cancer cells by reversing epithelial-to-mesenchymal transition by targeting β-catenin signaling.

Cancer
Zhou T et al (2017).
Oncol Rep.
DOI:
10.3892/or.2017.6011
PubMed:
29039569

Anti-oxidative and DNA protecting effects of flavonoids-rich Scutellaria lateriflora.

GeneticsPhytochemistry
Lohani M et al (2013).
Nat Prod Commun.
PubMed:
24354189

Comparative analysis of flavonoids and polar metabolites from hairy roots of Scutellaria baicalensis and Scutellaria lateriflora.

Phytochemistry
Kim JK et al (2014).
World J Microbiol Biotechnol.
DOI:
10.1007/s11274-013-1498-7
PubMed:
24162949

Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.

Review
Sarris J, McIntyre E and Camfield DA (2013).
CNS Drugs.
DOI:
10.1007/s40263-013-0059-9
PubMed:
23653088

A Medicinal Herb Scutellaria lateriflora Inhibits PrP Replication in vitro and Delays the Onset of Prion Disease in Mice.

Eiden M et al (2012).
Front Psychiatry.
DOI:
10.3389/fpsyt.2012.00009
PubMed:
22363300

Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence.

Review
Sarris J et al (2011).
Eur Neuropsychopharmacol.
DOI:
10.1016/j.euroneuro.2011.04.002
PubMed:
21601431