Senna occidentalis

Common Names: septicweed

Ethnobotanical Studies

Studies

Development of highly discriminatory SCoT- and CBDP-based SCAR fingerprint for authentication of Indian senna (Senna alexandrina Mill.) formerly Cassia angustifolia Vahl.).

Chouksey S et al (2024).
Front Plant Sci.
DOI:
10.3389/fpls.2024.1424665
PubMed:
39027666

Antimalarial Efficacy and Safety of Senna occidentalis (L.) Link Root Extract in Plasmodium berghei-Infected BALB/c Mice.

Mogaka S et al (2023).
Biomed Res Int.
DOI:
10.1155/2023/8296195
PubMed:
37583959

Characterization of a Novel Bacillus glycinifermentans Strain MGMM1 Based on Full Genome Analysis and Phenotypic Properties for Biotechnological Applications.

Genetics
Afordoanyi DM et al (2023).
Microorganisms.
DOI:
10.3390/microorganisms11061410
PubMed:
37374912

Medicinal plants used for treatment of malaria by indigenous communities of Tororo District, Eastern Uganda.

Tabuti JRS et al (2023).
Trop Med Health.
DOI:
10.1186/s41182-023-00526-8
PubMed:
37303066

Senna occidentalis (L.) Link root extract inhibits Plasmodium growth in vitro and in mice.

Mogaka S et al (2023).
BMC Complement Med Ther.
DOI:
10.1186/s12906-023-03854-8
PubMed:
36879244

In vitro study on efficacy of PHELA, an African traditional drug against SARS-CoV-2.

Summary

Researchers investigated an herbal combination of four African medicinal plants known as PHELA as a potential therapy for COVID-19. In vitro testing found that PHELA inhibited > 90% of SARS-CoV-2 and SARS-CoV infection as well as close to 100% of MERS-CoV infection. In silico docking studies showed strong binding energy interactions between compounds in PHELA and SARS-CoV-2 proteins. PHELA has potential as a COVID-19 therapeutic.

COVID-19
Matsabisa MG et al (2022).
Sci Rep.
DOI:
10.1038/s41598-022-13599-y
PubMed:
35718800

Investigating the phytotoxic potential of Verbesina encelioides: effect on growth and performance of co-occurring weed species.

Mehal KK et al (2023).
Protoplasma.
DOI:
10.1007/s00709-022-01761-2
PubMed:
35441891

De novo Transcriptome Assembly of Senna occidentalis Sheds Light on the Anthraquinone Biosynthesis Pathway.

Genetics
Kang SH et al (2022).
Front Plant Sci.
DOI:
10.3389/fpls.2021.773553
PubMed:
35046973

Structural analysis of extrafloral nectaries of Senna occidentalis L.: insights on diversity and evolution.

Afzal S et al (2021).
Planta.
DOI:
10.1007/s00425-021-03781-3
PubMed:
34807329

Hepatic encephalopathy in swine experimentally poisoned with Senna occidentalis seeds: Effects on astrocytes.

Summary

Senna occidentalis, a plant that can be ingested accidentally by humans and animals, was studied in a pig model. Pigs were fed rations containing 5%, 7.5%, and 10% S. occidentalis seeds for 7-11 days. All treated pigs showed symptoms of hepatoencephalopathy, including incoordination, ataxia, and anorexia. Biochemical changes were also observed, such as increased enzyme levels and higher serum bilirubin and ammonia levels. Microscopic analysis showed acute hepatocellular swelling, necrosis in various organs, and damage to astrocytes in the brain. This pig model could be used to study poisoning by S. occidentalis and other conditions leading to hepatoencephalopathy.

Neuroscience
Chileski GS et al (2021).
Toxicon.
DOI:
10.1016/j.toxicon.2021.08.018
PubMed:
34437876

Prioritization and selection of high fuelwood producing plant species at Boset District, Central Ethiopia: an ethnobotanical approach.

Ethnobotany
Bahru T, Kidane B and Tolessa A (2021).
J Ethnobiol Ethnomed.
DOI:
10.1186/s13002-021-00474-9
PubMed:
34399804

Unravelling unexplored diversity of cercosporoid fungi (Mycosphaerellaceae, Mycosphaerellales, Ascomycota) in tropical Africa.

Meswaet Y et al (2021).
MycoKeys.
DOI:
10.3897/mycokeys.81.67850
PubMed:
34177314

Nanopriming with phytosynthesized zinc oxide nanoparticles for promoting germination and starch metabolism in rice seeds.

Sharma D, Afzal S and Singh NK (2021).
J Biotechnol.
DOI:
10.1016/j.jbiotec.2021.06.014
PubMed:
34116127

Physiochemical, Insecticidal, and Antidiabetic Activities of Senna occidentalis Linn Root.

Diabetes
Issa TO et al (2020).
Biochem Res Int.
DOI:
10.1155/2020/8810744
PubMed:
33014467

Phytotoxic potential of Senna occidentalis (L.) Link extracts on seed germination and oxidative stress of Ipê seedlings.

da Silva ÍF and Vieira EA (2019).
Plant Biol (Stuttg).
DOI:
10.1111/plb.12969
PubMed:
30693622

Cardiotoxicity of Senna occidentalis in sheep (Ovis aries).

Cardiology
Lopes DI et al (2016).
Open Vet J.
PubMed:
26894038

Effects of long-term administration of Senna occidentalis seeds on the hematopoietic tissue of rats.

Teles AV, Fock RA and Górniak SL (2015).
Toxicon.
DOI:
10.1016/j.toxicon.2015.09.042
PubMed:
26435339