Common Names: great-leaved sida, `ilima
Sida cordifolia is a herb used in various traditional medicines. Its bioactive ingredients have therapeutic potential. Care because it may offer new treatments for a variety of human ailments.
Study investigated the effectiveness of Sida cordifolia L. roots in relieving neuropathic pain. Despite its traditional use, there is a lack of scientific evidence supporting this claim.
A study evaluated the effects of an extract from Sida cordifolia plant and its different fractions on rotenone-induced Parkinson's disease (PD) in rats. Biochemical and neurochemical changes were assessed in different brain regions, along with behavioral and histopathological evaluations. The most significant improvements were observed in the group treated with the aqueous fraction of the extract (AFSC). This fraction showed antioxidative properties, attenuating oxidative damage, eosinophilic lesions, and dopamine level decrease induced by rotenone. The study suggests the potential therapeutic use of AFSC in PD treatment due to its antioxidative actions.