Smilax china

Common Names: China root

Ethnobotanical Studies

Studies

Two New Phenylpropanoids and a Polyphenol with Anti-Cervical Cancer Activity from Smilax china L.

Summary

Novel phenylpropanoids from Smilax china L. showed significant cytotoxicity against HeLa cells, impacting mitochondrial function, ROS levels, cell migration, and cell-cycle progression. Compound 13 could be a promising treatment for cervical cancer.

CancerPhytochemistry
Hu L et al (2024).
Chem Biodivers.
DOI:
10.1002/cbdv.202401467
PubMed:
39166478

Jingangteng capsules ameliorate liver lipid disorders in diabetic rats by regulating microflora imbalances, metabolic disorders, and farnesoid X receptor.

Summary

Researchers studied the plant Smilax china L. (Jingangteng) and its use in treating gynecological inflammation. They found that Jingangteng capsules may regulate glucose and lipid metabolism, providing potential health benefits.

Diabetes
Chen M et al (2024).
Phytomedicine.
DOI:
10.1016/j.phymed.2024.155806
PubMed:
38876009

Effects of Smilax China L. extracts on Hyperuricemia chicken model via inhibiting xanthine oxidase activity.

Yan M et al (2024).
Poult Sci.
DOI:
10.1016/j.psj.2024.103887
PubMed:
38861845

Intestinal lymphatic transport of Smilax china L. pectic polysaccharide via Peyer's patches and its uptake and transport mechanisms in mononuclear phagocytes.

Gastroenterology
Liu J et al (2024).
Carbohydr Polym.
DOI:
10.1016/j.carbpol.2024.122256
PubMed:
38823922

Mechanism of Smilax china L. in the treatment of intrauterine adhesions based on network pharmacology, molecular docking and experimental validation.

Shi T et al (2024).
BMC Complement Med Ther.
DOI:
10.1186/s12906-024-04414-4
PubMed:
38580999

Metabolic Regulations of Smilax china L. against β-Amyloid Toxicity in Caenorhabditis elegans.

Yan L et al (2024).
Metabolites.
DOI:
10.3390/metabo14010049
PubMed:
38248852

Toxicity study of compound granules of Hedyotis diffusa: Acute toxicity and long-term toxicity.

Chen DH et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117434
PubMed:
37992881

An Ayurveda approach in the management of avascular necrosis of bilateral hip joint-A case report.

Singh SK, Rajoria K and Sharma S (2023).
J Ayurveda Integr Med.
DOI:
10.1016/j.jaim.2023.100792
PubMed:
37741160

Smilax china L.: A review of its botany, ethnopharmacology, phytochemistry, pharmacological activities, actual and potential applications.

Summary

Smilax china L., a commonly used traditional Chinese medicine, effectively treats pelvic inflammation and other inflammatory disorders, making it relevant for research and potential application in the lab.

Review Phytochemistry
Wang M et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116992
PubMed:
37541403

Identification of the Constituents of Ethyl Acetate Fraction from Smilax china L. and Determination of Xanthine Oxidase Inhibitory Properties.

Li X et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24065158
PubMed:
36982233

Smilax china L. Polyphenols Improves Insulin Resistance and Obesity in High-fat Diet-induced Mice Through IRS/AKT-AMPK and NF-κB Signaling Pathways.

Summary

SCP, derived from Smilax china L., reduces insulin resistance and obesity in mice by regulating gene and protein expressions involved in metabolism. It may have potential therapeutic value for lifestyle diseases.

ObesityPhytochemistry
Xu M et al (2023).
Plant Foods Hum Nutr.
DOI:
10.1007/s11130-023-01052-y
PubMed:
36826691

Smilax china root extract as a novel Glucose- 6-phosphate dehydrogenase inhibitor for the treatment of hepatocellular carcinoma.

Kanwal L et al (2022).
Saudi J Biol Sci.
DOI:
10.1016/j.sjbs.2022.103400
PubMed:
35991850

Quercetin, Engelitin and Caffeic Acid of Smilax china L. Polyphenols, Stimulate 3T3-L1 Adipocytes to Brown-like Adipocytes Via β3-AR/AMPK Signaling Pathway.

Phytochemistry
Kong L et al (2022).
Plant Foods Hum Nutr.
DOI:
10.1007/s11130-022-00996-x
PubMed:
35986845

A novel dibenzofuran from endophytic fungus Mycosphaerella nawae preferentially inhibits CD4(+) T cell activation and proliferation.

Immunology
Wang LW et al (2022).
J Appl Microbiol.
DOI:
10.1111/jam.15782
PubMed:
35973736

Eco-Stoichiometric Characteristics of Rhizosphere and Bulk Soils of Smilax china L. along Vertical Zone Spectrum of Fanjing Mountain.

Liu Y et al (2022).
Int J Environ Res Public Health.
DOI:
10.3390/ijerph19148693
PubMed:
35886545

Scopolin obtained from Smilax china L. against hepatocellular carcinoma by inhibiting glycolysis: A network pharmacology and experimental study.

Wang C, Zhou Q and Wu ST (2022).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2022.115469
PubMed:
35718053

Diosgenin: An Updated Pharmacological Review and Therapeutic Perspectives.

Review
Semwal P et al (2022).
Oxid Med Cell Longev.
DOI:
10.1155/2022/1035441
PubMed:
35677108

The inhibitory kinetics and mechanism of quercetin-3-O-rhamnoside and chlorogenic acid derived from Smilax china L. EtOAc fraction on xanthine oxidase.

Li X et al (2022).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2022.05.188
PubMed:
35660039

Smilax china L. Polysaccharide Alleviates Oxidative Stress and Protects From Acetaminophen-Induced Hepatotoxicity via Activating the Nrf2-ARE Pathway.

Wang K et al (2022).
Front Pharmacol.
DOI:
10.3389/fphar.2022.888560
PubMed:
35571121

Smilax China-derived yellow-fluorescent carbon dots for temperature sensing, Cu(2+) detection and cell imaging.

Chang D et al (2020).
Analyst.
DOI:
10.1039/d0an00102c
PubMed:
32096525

Smilax china L. rhizome extract inhibits nuclear factor-κB and induces apoptosis in ovarian cancer cells.

Cancer
Hu LL et al (2015).
Chin J Integr Med.
DOI:
10.1007/s11655-014-1788-9
PubMed:
25511428