Stellera chamaejasme

Ethnobotanical Studies

Studies

[Stellera chamaejasme against multidrug resistance of triple-negative breast cancer MDA-MB-231 cell through Nrf2].

Summary

SCL extract inhibits multidrug resistance in triple-negative breast cancer cells by suppressing Keap1/Nrf2 pathway, increasing ROS levels, and inducing apoptosis. Promising for overcoming drug resistance in breast cancer.

Cancer
Zeng R et al (2024).
Zhongguo Zhong Yao Za Zhi.
DOI:
10.19540/j.cnki.cjcmm.20231212.704
PubMed:
38812237

Toxic nonpreferred species accelerate the natural restoration of plant productivity and diversity in degraded grasslands.

Zheng X et al (2024).
Sci Total Environ.
DOI:
10.1016/j.scitotenv.2024.173391
PubMed:
38796004

Pleistocene glaciation advances the cryptic speciation of Stellera chamaejasme L. in a major biodiversity hotspot.

Rana SK et al (2024).
J Integr Plant Biol.
DOI:
10.1111/jipb.13663
PubMed:
38639466

High-throughput sequencing-based analysis of the composition and diversity of the endophyte community in roots of Stellera chamaejasme.

Zhang JZ et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-59055-x
PubMed:
38615120

Identification of toxic Gelsemium elegans in processed food and honey based on real-time PCR analysis.

Wang G et al (2024).
Food Res Int.
DOI:
10.1016/j.foodres.2024.114188
PubMed:
38519193

Stellera chamaejasme L. extract inhibits adipocyte differentiation through activation of the extracellular signal-regulated kinase pathway.

Yeon J et al (2024).
PLoS One.
DOI:
10.1371/journal.pone.0300520
PubMed:
38512891

Characterization of the Microbial Community Structures, Soil Chemical Properties, and Enzyme Activity of Stellera chamaejasme (Thymelaeaceae) and Its Associated Forages in Alpine Grassland of Northwestern China.

Jin H et al (2023).
Curr Microbiol.
DOI:
10.1007/s00284-023-03554-z
PubMed:
38097817

The Importance of Traditional Chinese Medicine in the Intervention and Treatment of HIV while Considering its Safety and Efficacy.

Shahrajabian MH and Sun W (2023).
Curr HIV Res.
DOI:
10.2174/011570162X271199231128092621
PubMed:
38047360

Characterization of SchTPSs Enables Construction of Yeast for the Bioproduction of α-Cadinol and the Related Sesquiterpenes.

Gao K et al (2023).
J Agric Food Chem.
DOI:
10.1021/acs.jafc.3c06394
PubMed:
37966253

Interactive effects between the invasive weed Stellera chamaejasme and grass: can arbuscular mycorrhizal fungi and fungal pathogens coregulate interspecific relationships?

Zhang R et al (2023).
Front Microbiol.
DOI:
10.3389/fmicb.2023.1236891
PubMed:
37711687

Comparative transcriptomes reveal geographic differences in the ability of the liver of plateau zokors (Eospalax baileyi) to respond and adapt to toxic plants.

Tan Y et al (2023).
BMC Genomics.
DOI:
10.1186/s12864-023-09642-5
PubMed:
37674113

Antioxidant and Anti-Inflammatory Activities of Stellera chamaejasme L. Roots and Aerial Parts Extracts.

Immunology
Selenge T et al (2023).
Life (Basel).
DOI:
10.3390/life13081654
PubMed:
37629511

Yuexiandajisu diterpenoids from Euphorbia ebracteolata Hayata (Langdu roots): An overview.

Review
Bailly C et al (2023).
Phytochemistry.
DOI:
10.1016/j.phytochem.2023.113784
PubMed:
37419377

[Stellera chamaejasme extract against multidrug resistance of breast cancer cell line MCF-7].

Summary

This study investigated the impact of Stellera chamaejasme extract (SCE) on multidrug resistance in breast cancer. They used two cell lines, one sensitive to chemotherapy and one resistant. The results showed that SCE significantly inhibited the proliferation of both cell lines and reduced drug resistance. Moreover, SCE induced apoptosis in the cells, as evidenced by nuclear changes and increased apoptotic cell proportions. Additionally, SCE promoted autophagy and altered the expression of proteins related to apoptosis and cell cycle regulation. These findings suggest that SCE may be effective in combating drug resistance in breast cancer cells.

Cancer
Cui XH et al (2023).
Zhongguo Zhong Yao Za Zhi.
DOI:
10.19540/j.cnki.cjcmm.20230103.701
PubMed:
37282865

Daphnane-type diterpenoids from Stellera chamaejasme L. and their inhibitory activity against hepatocellular carcinoma cells.

Cheng ZY et al (2023).
Phytochemistry.
DOI:
10.1016/j.phytochem.2023.113725
PubMed:
37224912

Endophytic Fungal Community of Stellera chamaejasme L. and Its Possible Role in Improving Host Plants' Ecological Flexibility in Degraded Grasslands.

Tang W et al (2023).
J Fungi (Basel).
DOI:
10.3390/jof9040465
PubMed:
37108919

Stelleratenoids A-F, macrocyclic daphnane orthoesters with anti-HIV activity from the roots of Stellera chamaejasme L.

Ding K et al (2023).
Phytochemistry.
DOI:
10.1016/j.phytochem.2023.113648
PubMed:
36963707

Diversity of sesquiterpenoids from Stellera chamaejasme with neuroprotective effects.

Summary

Researchers identified 20 sesquiterpenoids from the roots of Stellera chamaejasme, including six that showed neuroprotective effects on PC-12 cells damaged by sodium nitroprusside. One of these compounds, stelleraguaianone B, was found to reduce oxidative stress and promote mRNA expression of antioxidant enzymes. The study provides insights into potential natural compounds for treating neurological disorders caused by oxidative stress.

Neuroscience
Yuan FY et al (2023).
Phytochemistry.
DOI:
10.1016/j.phytochem.2023.113588
PubMed:
36693579

A novel anti-metastatic extract from Stellera chamaejasme Linn . suppresses breast tumor cell motility through inhibition of focal adhesion kinase.

Cancer
Du X et al (2022).
Chin Med J (Engl).
DOI:
10.1097/CM9.0000000000002311
PubMed:
36583616

Stellera chamaejasme L. extracts in the treatment of glioblastoma cell lines: Biological verification based on a network pharmacology approach.

Wang K et al (2022).
Front Oncol.
DOI:
10.3389/fonc.2022.962970
PubMed:
36059675

Biogeographic Patterns of Leaf Element Stoichiometry of Stelera chamaejasme L. in Degraded Grasslands on Inner Mongolia Plateau and Qinghai-Tibetan Plateau.

Guo L et al (2022).
Plants (Basel).
DOI:
10.3390/plants11151943
PubMed:
35893647

Daphnetin, a Coumarin in Genus Stellera Chamaejasme Linn: Chemistry, Bioactivity and Therapeutic Potential.

Review
Hang S et al (2022).
Chem Biodivers.
DOI:
10.1002/cbdv.202200261
PubMed:
35880614

Genomic divergence of Stellera chamaejasme through local selection across the Qinghai-Tibet plateau and northern China.

Hu H et al (2022).
Mol Ecol.
DOI:
10.1111/mec.16622
PubMed:
35869662

Stellerasespenes A‒E: Sesquiterpenoids from Stellera chamaejasme and their anti-neuroinflammatory effects.

Summary

Researchers have isolated nine sesquiterpenoids from Stellera chamaejasme roots, five of which are previously undescribed. These were tested for their ability to inhibit NO production in BV2 cells induced by LPS. Stellerasespene A was found to have higher inhibitory activity than minocycline, a positive control, indicating its potential use as an anti-inflammatory agent.

Neuroscience
Cheng ZY et al (2022).
Phytochemistry.
DOI:
10.1016/j.phytochem.2022.113275
PubMed:
35718134

Plateau zokors (Eospalax baileyi) respond to secondary metabolites from the roots of Stellera chamaejasme by enhancing hepatic inflammatory factors and metabolic pathway genes.

GeneticsImmunology
Tan Y et al (2022).
Comp Biochem Physiol C Toxicol Pharmacol.
DOI:
10.1016/j.cbpc.2022.109368
PubMed:
35589064

Endophytic bacterial community of Stellera chamaejasme L. and its role in improving host plants' competitiveness in grasslands.

Jiang Y et al (2022).
Environ Microbiol.
DOI:
10.1111/1462-2920.15897
PubMed:
35001475

Study on life histroy traits of Stellera chamaejasme provide insights into its control on degraded typical steppe.

Guo L et al (2021).
J Environ Manage.
DOI:
10.1016/j.jenvman.2021.112716
PubMed:
33957418

Effects of Stellera chamaejasme removal on the nutrient stoichiometry of S. chamaejasme-dominated grasslands in the Qinghai-Tibetan plateau.

Song M et al (2020).
PeerJ.
DOI:
10.7717/peerj.9239
PubMed:
32612880

Stellera chamaejasme and Its Main Compound Luteolin 7-O-Glucoside Alleviates Skin Lesions in Oxazolone- and 2,4-Dinitrochlorobenzene-Stimulated Murine Models of Atopic Dermatitis.

Dermatology
Jo BG et al (2019).
Planta Med.
DOI:
10.1055/a-0746-8698
PubMed:
30273950