Stephania cephalantha

Ethnobotanical Studies

Studies

Network pharmacology, molecular docking and experimental study of CEP in nasopharyngeal carcinoma.

Yang J et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117667
PubMed:
38159821

Cepharanthine, a regulator of keap1-Nrf2, inhibits gastric cancer growth through oxidative stress and energy metabolism pathway.

Summary

Cepharanthine (CEP) derived from Stephania Cephalantha Hayata inhibits gastric cancer cell growth by inducing apoptosis and cell cycle arrest. It also regulates oxidative stress and alters energy metabolism, suggesting potential for gastric cancer treatment.

CancerGastroenterologyImmunology
Lu YY et al (2023).
Cell Death Discov.
DOI:
10.1038/s41420-023-01752-z
PubMed:
38086844

Cepharanthine hydrochloride inhibits the Wnt/β‑catenin/Hedgehog signaling axis in liver cancer.

Cancer
Su GF et al (2022).
Oncol Rep.
DOI:
10.3892/or.2022.8294
PubMed:
35211762

Cepharanthine induces the proliferation of human dermal papilla cells and stimulates vascular endothelial growth factor expression through increased intracellular calcium mobilization and hypoxia-inducible factor activation.

Iwabuchi T et al (2021).
Clin Exp Dermatol.
DOI:
10.1111/ced.14533
PubMed:
33296524

Cepharanthine: An update of its mode of action, pharmacological properties and medical applications.

Review
Bailly C et al (2019).
Phytomedicine.
DOI:
10.1016/j.phymed.2019.152956
PubMed:
31132753

Cepharanthine Inhibits IFN-γ-Induced CXCL10 by Suppressing the JAK2/STAT1 Signal Pathway in Human Salivary Gland Ductal Cells.

Immunology
Aota K et al (2018).
Inflammation.
DOI:
10.1007/s10753-017-0662-x
PubMed:
28879548