Syzygium cumini

Common Names: Java plum

Ethnobotanical Studies

Studies

Molecular Dynamics Simulation Studies of Beta-Glucogallin and Dihydro Dehydro Coniferyl Alcohol from Syzygium cumini for its Antimicrobial Activity on Staphylococcus aureus.

Summary

Researchers explored phytochemicals from Syzygium cumini for potential efficacy against antimicrobial resistant Staphylococcus aureus. Beta-Glucogallin and Dihydro Dehydro Coniferyl alcohol showed strong interactions with the pathogen's ATP binding domain AgrC, making them promising candidates for new antibiotics against AMR infections.

Antimicrobial
Bhavyashree N et al (2024).
Cell Biochem Biophys.
DOI:
10.1007/s12013-024-01489-1
PubMed:
39214923

Syzygium cumini (L.) skeels mitigate diabetic nephropathy by regulating Nrf2 pathway and mitocyhondrial dysfunction: In vitro and in vivo studies.

Summary

SC homeopathic preparations show potential in managing diabetes by inhibiting AGE-RAGE interaction, reducing oxidative and inflammatory stress, and potentially preventing diabetic nephropathy.

Diabetes
Bangar NS et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118684
PubMed:
39127117

Extraction of Bioactive Compounds from the Fruits of Jambolan (Syzygium cumini (L.)) Using Alternative Solvents.

Artilha-Mesquita CAF et al (2024).
Plants (Basel).
DOI:
10.3390/plants13152065
PubMed:
39124183

Green Synthesis of Silver Nanoparticles from Syzygium cumini (L.) Skeels Seed Extract and their Potential Medicinal Applications.

Kavital A et al (2024).
Pharm Nanotechnol.
DOI:
10.2174/0122117385316957240710045706
PubMed:
39092639

Biosynthesized MgONPs using Syzygium cumini seed extract: Characterization, In vitro anti-oxidant and anti-microbial activity.

Summary

Tl;dr: Scientists used seed extracts to synthesize MgONPs with strong anti-oxidant and anti-microbial properties, potentially revolutionizing nanostructure formation. Important for developing new materials and medicines.

Antimicrobial
Kotakadi SM et al (2024).
Biotechnol Rep (Amst).
DOI:
10.1016/j.btre.2024.e00846
PubMed:
39034969

Evaluation of phytochemical profile, and antioxidant, antidiabetic activities of indigenous Thai fruits.

Summary

Thai fruits were analyzed for phenolics and flavonoids to explore their potential in treating type 2 diabetes. These lesser-known fruits could offer health benefits and be useful in diabetes management.

DiabetesImmunologyPhytochemistry
Prakulanon J et al (2024).
PeerJ.
DOI:
10.7717/peerj.17681
PubMed:
39011385

In-vitro and in-vivo investigation of wound healing efficacy of Syzygium cumini leaf extracts loaded carboxymethylcellulose film.

Ayyanar CB et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.133691
PubMed:
38972647

Characterization of Syzygium cumini (L.) Skeels (Jamun Seed) Particulate Fillers for Their Potential Use in Polymer Composites.

Thiagamani SMK et al (2024).
Molecules.
DOI:
10.3390/molecules29112618
PubMed:
38893494

Similar and divergent responses to salinity stress of jamun (Syzygium cumini L. Skeels) genotypes.

Singh A et al (2024).
PeerJ.
DOI:
10.7717/peerj.17311
PubMed:
38766484

Use of cerrado plants as an alternative in the control of bacterial contamination in the alcoholic fermentation process.

Lima MC et al (2024).
Braz J Biol.
DOI:
10.1590/1519-6984.281448
PubMed:
38695423

Compounds isolation from Syzygium cumini leaf extract against the Vibrio species in shrimp through bioassay-guided fractionation.

Ghosh AK et al (2024).
Nat Prod Res.
DOI:
10.1080/14786419.2024.2344192
PubMed:
38648539

Antimicrobial and antibiofilm effect of cannabinoids from Cannabis sativa against methicillin-resistant Staphylococcus aureus (MRSA) causing bovine mastitis.

Summary

Researchers identified Cannabis sativa L. as a potent inhibitor of MRSA, with cannabidiol and Δ9-THC showing bactericidal action. This plant-based alternative may help combat antimicrobial resistance in bovine biofilm-associated MRSA infections.

Antimicrobial
Roshan M et al (2024).
Int Microbiol.
DOI:
10.1007/s10123-024-00505-x
PubMed:
38568425

Anthelmintic screening of Bangladeshi medicinal plants and related phytochemicals using in vitro and in silico methods: An ethnobotanical perspective.

Summary

Researchers studied medicinal plants used by indigenous communities in Bangladesh for helminth infections. Discovering phytochemicals with anthelmintic activity could lead to new drugs to combat drug-resistant helminthiases in underdeveloped regions.

Ethnobotany
Khairuzzaman M et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118132
PubMed:
38565411

Green synthesis of cadmium oxide nanoparticles (CdO-NPS) using syzygium cumini: exploring industrial applications of CdO NPs as a corrosion inhibitor of mild steel in the acidic environment.

Sivalingam S et al (2024).
RSC Adv.
DOI:
10.1039/d4ra00560k
PubMed:
38454945

Encyclopaedic Review of Glipizide Pre-clinical and Clinical Status.

Mohammad S et al (2024).
Drug Res (Stuttg).
DOI:
10.1055/a-2237-8566
PubMed:
38408478

Effect of Syzygium cumini on Oxidative Stress Induced Cardiac Cellular Anomalies.

Summary

Researchers found that Syzygium cumini (Black berry) could be a natural way to protect the heart against Doxorubicin-induced damage. Its antioxidants and anti-inflammatory properties make it a promising option for cardio-oncological therapies.

CardiologyImmunology
Bhadana R and Rani V (2024).
Cardiovasc Hematol Agents Med Chem.
DOI:
10.2174/0118715257273859231211112731
PubMed:
38299280

Antimicrobial and Synergistic Effects of Syzygium cumini, Moringa oleifera, and Tinospora cordifolia Against Different Candida Infections.

Summary

Plant extracts showed strong antimicrobial activity against bacteria and fungi, including drug-resistant strains, and worked well with fluconazole. They could be a sustainable solution for infections.

Antimicrobial
Adelakun AO et al (2024).
Cureus.
DOI:
10.7759/cureus.52857
PubMed:
38274587

Development of chewing gum model system from phytocompounds of black jamun (Syzygium cumini) pulp and study of its dissolution kinetics.

Sharma M, Dash KK and Badwaik LS (2024).
J Food Sci Technol.
DOI:
10.1007/s13197-023-05841-w
PubMed:
38196719

Properties of active packaging of PLA-PCL film integrated with chitosan as an antibacterial agent and syzygium cumini seed extract as an antioxidant agent.

Immunology
Nasution H et al (2023).
Heliyon.
DOI:
10.1016/j.heliyon.2023.e23952
PubMed:
38192781

In vitro and in vivo studies of Syzygium cumini-loaded electrospun PLGA/PMMA/collagen nanofibers for accelerating topical wound healing.

Abdelazim EB et al (2024).
RSC Adv.
DOI:
10.1039/d3ra06355k
PubMed:
38173621

Mechanistic role of Syzygium cumini (L.) Skeels in glycation induced diabetic nephropathy via RAGE-NF-κB pathway and extracellular proteins modifications: A molecular approach.

Summary

Researchers investigated the molecular mechanism of Syzygium cumini's interaction with the AGEs-RAGE-NF-κB pathway. This ancient medicinal plant may be beneficial in treating diabetic nephropathy due to its anti-glycemic, anti-glycation, anti-inflammatory, and antioxidant properties.

DiabetesImmunology
Apte MM, Khattar E and Tupe RS (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117573
PubMed:
38110133

Medicinal plants used in the management of cancers by residents in the Elgon Sub-Region, Uganda.

Kudamba A et al (2023).
BMC Complement Med Ther.
DOI:
10.1186/s12906-023-04273-5
PubMed:
38087230

Comparative Study of Essential Oils from Different Organs of Syzygium cumini (Pamposia) Based on GC/MS Chemical Profiling and In Vitro Antiaging Activity.

Ashmawy NS, Gad HA and El-Nashar HAS (2023).
Molecules.
DOI:
10.3390/molecules28237861
PubMed:
38067590

Genome sequencing of Syzygium cumini (jamun) reveals adaptive evolution in secondary metabolism pathways associated with its medicinal properties.

Summary

Scientists sequenced the genome and transcriptome of a medicinal tree, revealing neopolyploidy and adaptive evolution in genes involved in secondary metabolite biosynthesis and stress tolerance mechanisms. This information is relevant for understanding the pharmacological properties of the tree, including its anti-diabetic effects.

Genetics
Chakraborty A et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1260414
PubMed:
38046611

Intra- and interspecific ecophysiological responses to waterlogging stress in two contrasting waterlogging-tolerant arbor species.

Tian M et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1257730
PubMed:
38023841

Assessment of air pollution tolerance potential of selected dicot tree species for urban forestry.

Sharma N et al (2023).
Environ Monit Assess.
DOI:
10.1007/s10661-023-12085-w
PubMed:
37950805

LARVICIDAL AND FUNGICIDAL ACTIVITY OF THE LEAF ESSENTIAL OIL OF FIVE MYRTACEAE SPECIES.

Summary

This study extracted and characterized essential oils (EOs) from Myrtaceae species. EOs from Eugenia species had high larvicidal activity against Aedes aegypti, while S. cumini showed strong fungicidal effects. Chemical diversity in these EOs contributes to their different biological activities.

Phytochemistry
Dos Santos FR et al (2023).
Chem Biodivers.
DOI:
10.1002/cbdv.202300823
PubMed:
37917799

Physicochemical and bioactive constituents, microbial counts, and color components of spray-dried Syzygium cumini L. pulp powder stored in different packaging materials under two controlled environmental conditions.

Summary

This study investigated the shelf life of spray-dried blackberry pulp powder in different packaging materials and storage conditions. It found that the 4-ply laminate was the best option for long-term storage, preserving the fruit's bioactive properties.

Phytochemistry
Kumar V et al (2023).
Front Nutr.
DOI:
10.3389/fnut.2023.1258884
PubMed:
37860034

In vitro antimalarial activity of Syzygium cumini fruit fraction.

Maslachah L and Purwitasari N (2023).
Open Vet J.
DOI:
10.5455/OVJ.2023.v13.i9.7
PubMed:
37842099

Hypoglycemic activity of Syzygium cumini (L.) Skeels seed extracts: an approach to in vitro, in vivo, and in silico studies.

Summary

Seed extracts were found to inhibit enzymes related to glucose metabolism and reduce blood glucose levels in rats. The acetone extract was most effective, and 1,2,3-Benzenetriol showed high affinity for human pancreatic α-amylase, indicating potential for managing diabetes.

Diabetes
Kavital A et al (2023).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2023.2268218
PubMed:
37819095

Syzygium cumini ameliorates high fat diet induced glucose intolerance, insulin resistance, weight gain, hepatic injury and nephrotoxicity through modulation of PTP1B and PPARγ signaling.

Thiyagarajan G et al (2023).
Environ Toxicol.
DOI:
10.1002/tox.23989
PubMed:
37815491

Syzygium cumini (L.) Extract-Derived Green Titanium Dioxide Nanoparticles Induce Caspase-Dependent Apoptosis in Hepatic Cancer Cells.

Summary

Green-synthesized titanium dioxide nanoparticles (TiO NPs) from seed extract were studied. Characterized by various techniques, the TiO NPs showed promising anticancer effects, inhibiting liver cancer cell growth and inducing apoptosis. This suggests potential for TiO NPs in cancer treatment.

Cancer
Rayzah M et al (2023).
Plants (Basel).
DOI:
10.3390/plants12183174
PubMed:
37765338

Production of tannase from a newly isolated yeast, Geotrichum cucujoidarum using agro-residues.

Thangavelu N et al (2023).
Prep Biochem Biotechnol.
DOI:
10.1080/10826068.2023.2256011
PubMed:
37698943

Exploring the Chemical and Biological Potential of Jamun (Syzygium cumini (L.) Skeels) Leaves: A Comprehensive Review.

Kumari N et al (2023).
Chem Biodivers.
DOI:
10.1002/cbdv.202300479
PubMed:
37667613

Protective Effect of Quercetin and p-Coumaric acid (p-CA) against Cardiotoxicity: an Insilico Study.

Bhadana R and Rani V (2023).
Recent Adv Food Nutr Agric.
DOI:
10.2174/2772574X14666230831100901
PubMed:
37653628

Ethnomedicinal Uses, Phytochemistry, and Anticancer Potentials of African Medicinal Fruits: A Comprehensive Review.

Summary

This review explores the use of African fruits in traditional medicine and their potential as anticancer agents. It emphasizes the importance of further research and suggests that these fruits could provide valuable phytochemicals for anticancer studies.

Review CancerEthnobotanyPhytochemistry
Fakudze NT et al (2023).
Pharmaceuticals (Basel).
DOI:
10.3390/ph16081117
PubMed:
37631032

Integrating traditional ecological knowledge into habitat restoration: implications for meeting forest restoration challenges.

Haq SM et al (2023).
J Ethnobiol Ethnomed.
DOI:
10.1186/s13002-023-00606-3
PubMed:
37559120

A new synonym of Bathseba Motschulsky, 1866 (Chrysomelidae, Eumolpinae, Typophorini) with a new species and redescription of B. bifasciata (Jacoby, 1895) n. comb. and other taxonomic and biological notes.

Kumari A, Moseyko SAG and Prathapan KD (2023).
Zootaxa.
DOI:
10.11646/zootaxa.5293.1.5
PubMed:
37518494

Nanoengineering TiO(2) for evaluating performance in dye sensitized solar cells with natural dyes.

Khan MJ et al (2023).
RSC Adv.
DOI:
10.1039/d3ra02927a
PubMed:
37501775

An ethnobotanical survey on phytomedicines based on traditional knowledge in the Barpeta district, Assam, India.

Ethnobotany
Bhattacharjya DK et al (2023).
J Ayurveda Integr Med.
DOI:
10.1016/j.jaim.2023.100763
PubMed:
37478633

The combined effect of EGR and hydrogen addition on a Syzygium cumini (jamun) liquid biofuel engine.

Kannappan C, Sengottaiyan S and Ramasamy R (2023).
Biotechnol Biofuels Bioprod.
DOI:
10.1186/s13068-023-02330-2
PubMed:
37355616

A multivariate and quantitative assessment of medicinal plants used by the indigenous Malayali tribes in the Javadhu hills of Tiruvannamalai district, Tamil Nadu, India.

Silambarasan R et al (2023).
Heliyon.
DOI:
10.1016/j.heliyon.2023.e15607
PubMed:
37305490

Dietary Syzygium cumini leaf extract influences growth performance, immunological responses and gene expression in pathogen-challenged Cyprinus carpio.

Genetics
Giri SS et al (2023).
Fish Shellfish Immunol.
DOI:
10.1016/j.fsi.2023.108830
PubMed:
37244318

Combined Pulsed Vacuum Osmotic Dehydration and Convective Air-Drying Process of Jambolan Fruits.

Araújo AL and Pena RDS (2023).
Foods.
DOI:
10.3390/foods12091785
PubMed:
37174323

A review of novel green adsorbents as a sustainable alternative for the remediation of chromium (VI) from water environments.

Review
Anjum A et al (2023).
Heliyon.
DOI:
10.1016/j.heliyon.2023.e15575
PubMed:
37153391

Exploring the multipotentiality of plant extracts for the green synthesis of iron nanoparticles: A study of adsorption capacity and dye degradation efficiency.

Kumari T, Deepak and Shukla V (2023).
Environ Res.
DOI:
10.1016/j.envres.2023.116025
PubMed:
37127105

Greater efficiency of polyherbal drug encapsulated biosynthesized chitosan nano-biopolymer on diabetes and its complications.

Diabetes
Revathi G et al (2023).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.124445
PubMed:
37060982

Influence of bio fabricated manganese oxide nanoparticles for effective callogenesis of Moringa oleifera Lam.

Nawaz QU et al (2023).
Plant Physiol Biochem.
DOI:
10.1016/j.plaphy.2023.107671
PubMed:
37028241

Reconnoitring the antioxidant and anti-bacterial potential of different fruits after tannin acyl hydrolase mediated biotransformation.

Immunology
Rippin R, Sharma AK and Beniwal V (2023).
Biotechnol Appl Biochem.
DOI:
10.1002/bab.2461
PubMed:
36965069

Fabrication and characterization of gelatin-based nanocomposite edible film prepared from eggshell with anthocyanin as pH indicator to assure quality of food.

Priyadharshee M and Preetha R (2023).
J Food Sci Technol.
DOI:
10.1007/s13197-023-05685-4
PubMed:
36936121

Antibacterial Potential of Gold Nanoparticles Synthesized From Leaf Extract of Syzygium cumini Against Multidrug-Resistant Urinary Tract Pathogens.

Diksha D et al (2023).
Cureus.
DOI:
10.7759/cureus.34830
PubMed:
36919069

Efficiency of Different Solvents in the Extraction of Bioactive Compounds from Plinia cauliflora and Syzygium cumini Fruits as Evaluated by Paper Spray Mass Spectrometry.

Correia VTDV et al (2023).
Molecules.
DOI:
10.3390/molecules28052359
PubMed:
36903602

Physical and functional stability of spray-dried jamun (Syzygium cumini L) juice powder produced with different carrier agents.

Shelke G et al (2023).
J Texture Stud.
DOI:
10.1111/jtxs.12749
PubMed:
36883842

Data from the batch adsorption of ciprofloxacin and lamivudine from synthetic solution using jamun seed (Syzygium cumini) biochar: Response surface methodology (RSM) optimization.

Ripanda A et al (2023).
Data Brief.
DOI:
10.1016/j.dib.2023.108975
PubMed:
36875218

Molecular Fingerprinting and Phytochemical Investigation of Syzygium cumini L. from Different Agro-Ecological Zones of India.

Phytochemistry
Khan S et al (2023).
Plants (Basel).
DOI:
10.3390/plants12040931
PubMed:
36840279

Encapsulation of Cymbopogon khasiana × Cymbopogon pendulus Essential Oil (CKP-25) in Chitosan Nanoemulsion as a Green and Novel Strategy for Mitigation of Fungal Association and Aflatoxin B(1) Contamination in Food System.

Phytochemistry
Prasad J et al (2023).
Foods.
DOI:
10.3390/foods12040722
PubMed:
36832806

Long-Term Supplementation of Syzygium cumini (L.) Skeels Concentrate Alleviates Age-Related Cognitive Deficit and Oxidative Damage: A Comparative Study of Young vs. Old Mice.

Summary

(L.) Skeels, a fruit known for its medicinal properties, has been found to have significant protective effects against age-related neurological changes in mice. After analyzing the fruit's phytochemicals, young mice were supplemented with different concentrations of the fruit for 16 months. The mice showed improved cognitive function and behavior, along with low levels of malondialdehyde and acetylcholinesterase and elevated antioxidant enzymes. This may be due to the antioxidant and anticholinergic effects of phytocompounds identified in the fruit. These findings suggest potential benefits of (L.) Skeels in preventing age-associated amnesia.

Neuroscience
Malik N et al (2023).
Nutrients.
DOI:
10.3390/nu15030666
PubMed:
36771374

Selection of the promising accessions of jamun (Syzygium cumini (L.) skeels) based on pomological characterizations.

Khadivi A et al (2022).
Food Sci Nutr.
DOI:
10.1002/fsn3.3078
PubMed:
36655090

Astounding Health Benefits of Jamun (Syzygium cumini) toward Metabolic Syndrome.

Review
Rizvi MK et al (2022).
Molecules.
DOI:
10.3390/molecules27217184
PubMed:
36364010

Dissecting the below- and aboveground specific responses of two waterlogging-tolerant arbor species to nutrient supply under waterlogging conditions.

Li D et al (2023).
Tree Physiol.
DOI:
10.1093/treephys/tpac127
PubMed:
36300499

Trunk Disease Fungi Associated with Syzygium cumini in Iran.

Panahandeh S, Mohammadi H and Gramaje D (2019).
Plant Dis.
DOI:
10.1094/PDIS-06-18-0923-RE
PubMed:
30777803

Syzygium cumini (L.) skeels: a prominent source of bioactive molecules against cardiometabolic diseases.

Review Cardiology
Chagas VT et al (2015).
Front Pharmacol.
DOI:
10.3389/fphar.2015.00259
PubMed:
26578965

Pharmacological potentials of Syzygium cumini: a review.

Review
Srivastava S and Chandra D (2013).
J Sci Food Agric.
DOI:
10.1002/jsfa.6111
PubMed:
23460190