Common Names: Aztec marigold, French marigold
"Study on Tagetes erecta L. fruit oils from Iran: potent cytotoxic activity on glioblastoma cells, and significant inhibition of PI3K/AKT/mTOR signaling pathway. Potential as an anticancer agent. Important for cancer research."
Study on marigold flower effluent identified compounds inhibiting fungal pathogens in crop plants. Treated effluents showed 10-32% inhibition, untreated 37-92%. Potential for new plant protection methods.
Scientists researched a potential skin-whitening agent from Tagetes erecta L. flowers. The extract showed promising results in inhibiting melanogenesis, which could lead to new safe and effective cosmetic ingredients.
An extract from edible flower petals was found to have antioxidant and antitumoral effects on ovarian cancer cells and show promise in treating Alzheimer's disease. Flower petals may be a potential source of polyphenols for biomedical use.
Floral waste from marigold flowers is used to create a hydrogel that has self-healing ability, enhanced antioxidant and anti-inflammatory properties, and controlled release of a drug for colorectal cancer treatment. This study highlights the potential of using floral waste for colon cancer remedy.
Researchers created a water-soluble lutein beverage with Chinese wolfberry and chrysanthemum that improved crystalline lenses, reduced visual fatigue, and increased antioxidant enzymes in diabetic rats. This beverage is a safe and effective way to enhance anti-oxidation capacity and relieve visual fatigue. (42 words)
Plant extract shows potential as a therapeutic option for lung cancer, with cytotoxic effects on tumor cells, reduced tumor growth, and improved chemotherapy effectiveness.
Scientists discovered and cloned seven TeCYC2 genes in marigold, altering the symmetry of Arabidopsis flowers when expressed, revealing their interaction and potential applications in molecular breeding for varied flower forms.
Researchers have found that quercetagitrin, a natural compound from African marigold, can inhibit tau aggregation and reduce tau phosphorylation in vitro. In vivo studies showed that oral administration of the compound restored cognitive deficits and neuron loss and prevented the formation of NFTs and tau phosphorylations in P301S-tau transgenic mice. Quercetagitrin also inhibited neuroinflammation through the inhibition of NF-κB activation. These findings suggest that quercetagitrin has potential as a therapeutic medicine for Alzheimer's disease and other tauopathies.
Researchers conducted a systematic review of scientific articles published between 2010 and 2020 that evaluated the anxiolytic, sedative, and/or hypnotic effects of flower extracts in pre-clinical animal models. They found that some flower extracts have an anxiolytic effect comparable to diazepam, but their therapeutic utility in anxiety disorders needs more investigation. The study compiled the characteristics of anxiety studies in animal models, evaluated locomotor activity, and the hypnotic effect of the extracts. The study revealed that matricaria chamomilla had a sedative effect, and 23 other flower plants had anxiolytic effects. However, more reliable behavioral tests and better experimental designs are needed to obtain more conclusive evidence with clinical significance.
Researchers obtained a polyphenolic-rich extract from Tageres erecta flowers. In vitro and in vivo experiments showed potential anti-diabetic and anti-obesity effects. Polyphenols from T. erecta can be considered as bioactive compounds for preventing metabolic chronic diseases.