Common Names: English yew, European yew
Scientists overexpressed two bottleneck enzymes (BAPT and DBTNBT) in Taxus baccata roots, resulting in higher paclitaxel production. DBTNBT line produced over four times more paclitaxel (310 mg/L) than wild type, while BAPT line almost doubled the taxane content (135 mg/L). Increased expression of key biosynthetic genes was observed.