Taxus chinensis

Ethnobotanical Studies

Studies

Improving regioselectivity of phenylalanine aminomutase from Taxus chinensis by semi-rational mutagenesis for the biocatalytic amination of cinnamates.

Tang T et al (2024).
Front Bioeng Biotechnol.
DOI:
10.3389/fbioe.2024.1417962
PubMed:
39239258

Comparative study of the antibacterial effects of wound secretions of different cultivars of Chinese fir.

Jiang Y et al (2024).
PeerJ.
DOI:
10.7717/peerj.17850
PubMed:
39161966

Taxus chinensis var. mairei (Lemée et Lévl) Cheng et L.K. Fu overcomes the resistance to osimertinib in EGFR-mutant non-small-cell lung cancer via suppression of ERK1/2-related cholesterol biosynthesis.

Cancer
Dai S et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118586
PubMed:
39032664

Draft genome of carotenoid-producing endophytic Pseudomonas sp. 102515 from Taxus chinensis.

Summary

Draft genome sequence of endophytic sp. 102515 isolated from . Genome is 4.9 Mbp with 36 contigs, 66% GC content, 918.9 kbp plasmid, and 2 rRNA operons. Study can provide insights into plant-microbe interactions and potential agricultural applications.

Genetics
Fidan O et al (2024).
Microbiol Resour Announc.
DOI:
10.1128/mra.00139-24
PubMed:
38940526

Antifungal activity and possible mechanism of Streptomyces nojiriensis 9-13 against Mycogone sp., causing wet bubble disease on Agaricus bisporus.

Summary

Strain 9-13, identified as Streptomyces nojiriensis, shows strong inhibitory activity against Mycogone species causing Wet Bubble Disease in Agaricus bisporus. Extracts destroy fungal cells, reducing disease severity by up to 87.32%. Potential biocontrol agent for mushroom production.

Antimicrobial
Shi N et al (2024).
Plant Dis.
DOI:
10.1094/PDIS-03-24-0645-RE
PubMed:
38885024

[Advances in paclitaxel biosynthesis and transcriptional regulation mechanisms].

Review
Sun F et al (2024).
Sheng Wu Gong Cheng Xue Bao.
DOI:
10.13345/j.cjb.230850
PubMed:
38783804

Regulatory microRNAs and phasiRNAs of paclitaxel biosynthesis in Taxus chinensis.

Sun MS et al (2024).
Front Plant Sci.
DOI:
10.3389/fpls.2024.1403060
PubMed:
38779066

Metabolomics analysis of different diameter classes of Taxus chinensis reveals that the resource allocation is related to carbon and nitrogen metabolism.

Pan L et al (2024).
BMC Plant Biol.
DOI:
10.1186/s12870-024-05070-z
PubMed:
38724888

Importance of plant and fruit traits on the structure of bird seed dispersal networks in different disturbed habitats.

Wang Z et al (2024).
Integr Zool.
DOI:
10.1111/1749-4877.12822
PubMed:
38488176

Paclitaxel combined with Compound K inducing pyroptosis of non-small cell lung cancer cells by regulating Treg/Th17 balance.

Summary

Researchers found that the compound taxus chinensis capsule (CTC) can alter the balance of immune cells in cancer patients, potentially improving efficacy of immunotherapy. This could lead to new drug development for overcoming resistance to current treatments.

Cancer
Wang H et al (2024).
Chin Med.
DOI:
10.1186/s13020-024-00904-2
PubMed:
38360696

In Silico Insights into Micro-Mechanism Understanding of Extracts of Taxus Chinensis Fruits Against Alzheimer's Disease.

Summary

Researchers investigated the potential of taxus chinensis fruit (TCF) in treating Alzheimer's disease (AD). They identified the constituents and targets associated with AD. Relevant for potential AD treatment.

Neuroscience
Chen M et al (2024).
J Alzheimers Dis.
DOI:
10.3233/JAD-231066
PubMed:
38217605

Integrated bioinformatics and network pharmacology to explore the therapeutic target and molecular mechanisms of Taxus chinensis against non-small cell lung cancer.

Summary

Bioinformatics study identifies 401 targets in cancer, MAPK signaling, and PI3K/Akt signaling pathways that Taxus chinensis (TC) binds to, potentially making it an effective treatment for lung cancer.

Cancer
Zhang S, Wang J and Zhang H (2023).
Medicine (Baltimore).
DOI:
10.1097/MD.0000000000035826
PubMed:
37933017

Targeted control of supporting pathways in paclitaxel biosynthesis with CRISPR-guided methylation.

Summary

Scientists used CRISPR-guided DNA methylation and chemical inhibitors to control the phenylpropanoid pathway in plant cell cultures, increasing production of paclitaxel, an anticancer drug. This method can be used for metabolic engineering in plant cell cultures to produce valuable compounds.

Genetics
Brzycki Newton C, Young EM and Roberts SC (2023).
Front Bioeng Biotechnol.
DOI:
10.3389/fbioe.2023.1272811
PubMed:
37915547

Large-Scale Identification and Characterization Analysis of VQ Family Genes in Plants, Especially Gymnosperms.

Genetics
Tian J, Zhang J and Francis F (2023).
Int J Mol Sci.
DOI:
10.3390/ijms241914968
PubMed:
37834416

Neuroprotective α-pyrones from Nigrospora oryzae, an endophytic fungus residing in Taxus chinensis var. mairei.

Summary

Scientists discovered eight previously unknown pyrones and six known pyrones from an endophytic fungus. Some of these pyrones show potential as neuroprotective agents, making this research important for understanding natural chemical diversity and expanding biofunction possibilities.

Neuroscience
Fan ZY et al (2023).
Phytochemistry.
DOI:
10.1016/j.phytochem.2023.113873
PubMed:
37769958

Insights from multi-omics integration into seed germination of Taxus chinensis var mairei.

Chen L et al (2023).
Commun Biol.
DOI:
10.1038/s42003-023-05307-x
PubMed:
37697020

miR5298b regulated taxol biosynthesis by acting on TcNPR3, resulting in an alleviation of the strong inhibition of the TcNPR3-TcTGA6 complex in Taxus chinensis.

Ying C et al (2023).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.125909
PubMed:
37482165

Alleviation of Shade Stress in Chinese Yew (Taxus chinensis) Seedlings with 5-Aminolevulinic Acid (ALA).

Wu L et al (2023).
Plants (Basel).
DOI:
10.3390/plants12122333
PubMed:
37375957

Effects of seasonal temperature regimes on embryo growth and endogenous hormones of Taxus chinensis var. mairei seeds.

Zhou M et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1114629
PubMed:
36938041

Fermentative Production of Diacylglycerol by Endophytic Fungi Screened from Taxus chinensis var. mairei.

Xu W et al (2023).
Foods.
DOI:
10.3390/foods12020399
PubMed:
36673491

First report of leaf spot on Elaeagnus pungens caused by Neopestalotiopsis clavispora in China.

Qi XL et al (2022).
Plant Dis.
DOI:
10.1094/PDIS-10-22-2457-PDN
PubMed:
36510420

Transcriptome analysis provides insights into light condition effect on paclitaxel biosynthesis in yew saplings.

Genetics
Li T et al (2022).
BMC Plant Biol.
DOI:
10.1186/s12870-022-03958-2
PubMed:
36503377

Investigation of bioactivities of Taxus chinensis, Taxus cuspidata, and Taxus × media by gas chromatography-mass spectrometry.

Phytochemistry
Zhang S et al (2021).
Open Life Sci.
DOI:
10.1515/biol-2021-0032
PubMed:
33817320

Response of rhizosphere bacterial community of Taxus chinensis var. mairei to temperature changes.

Yu X, Liu X and Liu X (2019).
PLoS One.
DOI:
10.1371/journal.pone.0226500
PubMed:
31830112

Transcriptome Assembly and Systematic Identification of Novel Cytochrome P450s in Taxus chinensis.

Genetics
Liao W et al (2017).
Front Plant Sci.
DOI:
10.3389/fpls.2017.01468
PubMed:
28878800

Transcriptomic Response of Chinese Yew (Taxus chinensis) to Cold Stress.

Meng D et al (2017).
Front Plant Sci.
DOI:
10.3389/fpls.2017.00468
PubMed:
28503178

Characteristic and protection of rare and endangered Taxus chinensis var. maireiin the Taihang Mountains.

Zaiyou J et al (2016).
Nutr Hosp.
DOI:
10.20960/nh.281
PubMed:
27513508

Transcriptional profile of Taxus chinensis cells in response to methyl jasmonate.

Li ST et al (2012).
BMC Genomics.
DOI:
10.1186/1471-2164-13-295
PubMed:
22748077

Taxoids from Taxus chinensis.

Zhao Y et al (2006).
J Nat Prod.
PubMed:
17190468