Terminalia bellirica

Common Names: myrobalan

Ethnobotanical Studies

Studies

Terminalia bellirica (Gaertn.) Roxb. extracts reshape the perifollicular microenvironment and regulate the MAPK pathway for androgenetic alopecia treatment.

Summary

Researchers studied the medicinal effects of Terminalia bellirica on male pattern baldness. TBR has multiple pharmacological activities and could potentially be used for AGA treatment.

Xiang H et al (2024).
J Ethnopharmacol.
PubMed:
39236776

Terminalia bellirica and Andrographis paniculata dietary supplementation in mitigating heat stress-induced behavioral, metabolic and genetic alterations in broiler chickens.

Fayed RH et al (2024).
BMC Vet Res.
PubMed:
39227945

How can dry tropical forests respond to climate change? Predictions for key Non-Timber Forest Product species show different trends in India.

Saraf PN et al (2024).
Environ Monit Assess.
PubMed:
38995471

Computational identification of potential bioactive compounds from Triphala against alcoholic liver injury by targeting alcohol dehydrogenase.

Banjan B et al (2024).
Mol Divers.
PubMed:
38743308

Green synthesized silver nanoparticles of Terminalia bellirica leaves extract: synthesis, characterization, in-silico studies, and antimalarial activity.

Singh S et al (2024).
Artif Cells Nanomed Biotechnol.
PubMed:
38696111

Herbal-Based Green Synthesis of TB-ZnO-TiO(II) Nanoparticles Composite From Terminalia bellirica: Characterization, Toxicity Assay, Antioxidant Assay, and Antimicrobial Activity.

Summary

Tb-ZnO-TiO NPs composite from leaf extract showed strong antioxidant and antibacterial properties with low toxicity, making them promising for drug delivery and antimicrobial applications.

Shivalingam C et al (2024).
Cureus.
PubMed:
38586786

Cold maceration extraction of wild fruit Terminalia bellirica (Gaertn.) Roxb.: exploring its bioactives for biomedical applications.

Nerlekar N et al (2024).
Prep Biochem Biotechnol.
PubMed:
38349742

Preventive mechanisms of Chinese Tibetan medicine Triphala against nonalcoholic fatty liver disease.

Jiang Y et al (2023).
Phytomedicine.
PubMed:
38006804

Terminalia bellirica Fruit Extract Alleviates DSS-Induced Ulcerative Colitis by Regulating Gut Microbiota, Inflammatory Mediators, and Cytokines.

Summary

This study found that ethyl acetate extract from fruits has anti-inflammatory effects and can alleviate symptoms of ulcerative colitis. It also suggests TBEA could be developed into a new drug for treating UC.

Li YY et al (2023).
Molecules.
PubMed:
37570753

The In Vivo and In Vitro Effects of Terminalia bellirica (Gaertn.) Roxb. Fruit Extract on Testosterone-Induced Hair Loss.

Summary

In this study, the researchers investigated the effects of (Gaertn.) Roxb. (TBE) on testosterone-inhibited hair growth. They found that TBE increased hair growth and was more effective than a commercial treatment. This suggests that TBE could be a promising option for treating hair loss and promoting hair growth.

Woo MJ et al (2023).
J Microbiol Biotechnol.
PubMed:
37482816

Protective effects of the Terminalia bellirica tannin-induced Nrf2/HO-1 signaling pathway in rats with high-altitude pulmonary hypertension.

Summary

Tannins in Terminalia bellirica protect against oxidative stress and inflammation induced by high-altitude hypoxia, potentially preventing high-altitude pulmonary hypertension.

Aimaier S et al (2023).
BMC Complement Med Ther.
PubMed:
37149589

Octyl Gallate and Gallic Acid Isolated from Terminalia bellirica Circumvent Breast Cancer Progression by Enhancing the Intrinsic Apoptotic Signaling Pathway and Elevating the Levels of Anti-oxidant Enzymes.

Vijayalakshmi P et al (2023).
Appl Biochem Biotechnol.
PubMed:
36988844

Comparative Analysis of Traditional Oriental Herbal Fruits as Potential Sources of Polyphenols and Minerals for Nutritional Supplements.

Quesada-Granados JJ et al (2023).
Molecules.
PubMed:
36985653

Low Temperature In Situ Synthesis of ZnO Nanoparticles from Electric Arc Furnace Dust (EAFD) Waste to Impart Antibacterial Properties on Natural Dye-Colored Batik Fabrics.

Eskani IN et al (2023).
Polymers (Basel).
PubMed:
36772047

Preventive effect of Terminalia bellirica (Gaertn.) Roxb. extract on mice infected with Salmonella Typhimurium.

Kong Q et al (2023).
Front Cell Infect Microbiol.
PubMed:
36699727

Terminalia bellirica ethanol extract ameliorates nonalcoholic fatty liver disease in mice by amending the intestinal microbiota and faecal metabolites.

Zhang B et al (2023).
J Ethnopharmacol.
PubMed:
36581163

Supplementation with the Traditional Thai Polyherbal Medicine NawaTab Ameliorates Lipid Profiles in High-Fat Diet-Induced Hyperlipidemic Rats.

Niyomchan A et al (2022).
Evid Based Complement Alternat Med.
PubMed:
36452138

Effect of Autochthonous Nepalese Fruits on Nutrient Degradation, Fermentation Kinetics, Total Gas Production, and Methane Production in In-Vitro Rumen Fermentation.

Dhakal R et al (2022).
Animals (Basel).
PubMed:
36077918

Tannins in Terminalia bellirica inhibits hepatocellular carcinoma growth via re-educating tumor-associated macrophages and restoring CD8(+)T cell function.

Chang Z et al (2022).
Biomed Pharmacother.
PubMed:
36057223

A validated spectro densitometric regulatory compliant USP-HP-TLC protocol for quantification of polyphenols and antioxidants from polyherbal formulations containing Terminalia species.

Bidikar CM et al (2022).
J Chromatogr B Analyt Technol Biomed Life Sci.
PubMed:
35940042

Exploring scientific validation of Triphala Rasayana in ayurveda as a source of rejuvenation for contemporary healthcare: An update.

Review
Ahmed S, Ding X and Sharma A (2021).
J Ethnopharmacol.
PubMed:
33465446

Aceclofenac-induced hepatotoxicity: An ameliorative effect of Terminalia bellirica fruit and ellagic acid.

Gupta A and Pandey AK (2020).
World J Hepatol.
PubMed:
33312421

Terminalia bellirica (Gaertn.) roxb. (Bahera) in health and disease: A systematic and comprehensive review.

Gupta A et al (2020).
Phytomedicine.
PubMed:
32781393

Chemical composition, antioxidant and hepatoprotective activities of methanol extracts from leaves of Terminalia bellirica and Terminalia sericea (Combretaceae).

Sobeh M et al (2019).
PeerJ.
PubMed:
30834179

Terminalia bellirica (Gaertn.) Roxb. Extract and Gallic Acid Attenuate LPS-Induced Inflammation and Oxidative Stress via MAPK/NF-κB and Akt/AMPK/Nrf2 Pathways.

Tanaka M et al (2018).
Oxid Med Cell Longev.
PubMed:
30533177

Terminalia bellirica fruit extracts: in-vitro antibacterial activity against selected multidrug-resistant bacteria, radical scavenging activity and cytotoxicity study on BHK-21 cells.

Dharmaratne MPJ et al (2018).
BMC Complement Altern Med.
PubMed:
30526562

Terminalia bellirica (Gaertn.) Roxb fruit exerts anti-inflammatory effect via regulating arachidonic acid pathway and pro-inflammatory cytokines in lipopolysaccharide-induced RAW 264.7 macrophages.

Jayesh K et al (2018).
Inflammopharmacology.
PubMed:
30003465

In vivo toxicity evaluation of aqueous acetone extract of Terminalia bellirica (Gaertn.) Roxb. fruit.

Jayesh K et al (2017).
Regul Toxicol Pharmacol.
PubMed:
28389325

Anti Bacterial Efficacy of Terminalia Chebula, Terminalia Bellirica, Embilica Officinalis and Triphala on Salivary Streptococcus Mutans Count - A Linear Randomized Cross Over Trial.

Saxena S et al (2017).
J Clin Diagn Res.
PubMed:
28384980

Terminalia bellirica Extract Inhibits Low-Density Lipoprotein Oxidation and Macrophage Inflammatory Response in Vitro.

Tanaka M et al (2016).
Antioxidants (Basel).
PubMed:
27314393