Common Names: mother of thyme
Researchers evaluated the anti-acetylcholinesterase (AChE) and antioxidant activities of extracts and essential oils from Cyclotrichium niveum, Thymus praecox subsp. caucasicus var. caucasicus, Echinacea purpurea, and E. pallida. They found that ethyl acetate and dichloromethane extracts of CN had the highest AChE inhibition while ethyl acetate and ethanol extracts of TP showed significant antioxidant activity. Water extracts of CN and TP and the chloroform extract of EPU displayed the highest ferrous ion-chelating effect. TP's leaf and flower essential oils had the best antioxidant power. These findings suggest that these plant extracts and oils may have potential therapeutic applications.
This study investigated the ability of Icelandic medicinal herbs to inhibit acetylcholinesterase (AChE). Two extracts, Angelica archangelica seeds and Geranium sylvaticum aerial parts, were effective in inhibiting AChE. Xanthotoxin from A. archangelica was more potent than imperatorin. However, furanocoumarins likely played a minor role in the extract's total activity. A synergistic effect was observed when the extracts of A. archangelica and G. sylvaticum were combined. Other medicinal herbs did not show AChE inhibitory activity. This research highlights the potential of these specific Icelandic herbs for developing treatments for disorders associated with AChE inhibition, such as Alzheimer's disease.