Trichosanthes tricuspidata

Ethnobotanical Studies

Studies

Comparative Assessment of Three Medicinal Plants against Diabetes and Oxidative Stress Using Experimental and Computational Approaches.

Shah MS et al (2023).
Evid Based Complement Alternat Med.
PubMed:
37143510

Corrigendum to "Trichosanthes tricuspidata Lour. Methanol Extract Exhibits Anti-Inflammatory Activity by Targeting Syk, Src, and IRAK1 Kinase Activity".

Ahuja A et al (2020).
Evid Based Complement Alternat Med.
PubMed:
33343672

Trichosanthes tricuspidata Lour. Methanol Extract Exhibits Anti-Inflammatory Activity by Targeting Syk, Src, and IRAK1 Kinase Activity.

Ahuja A et al (2019).
Evid Based Complement Alternat Med.
PubMed:
31929819

Photoscopic characterization of green synthesized silver nanoparticles from Trichosanthes tricuspidata and its antibacterial potential.

Yuvarajan R et al (2015).
J Photochem Photobiol B.
PubMed:
26044176

Trichosanthes tricuspidata modulates oxidative toxicity in brain hippocampus against pilocarpine induced status epilepticus in mice.

Summary

Researchers aimed to assess the impact of Trichosanthes tricuspidata methanolic extract (TTME) on seizures in mice induced by pilocarpine and the resulting oxidative stress. Pilocarpine caused seizures and increased lipid peroxidation, hippocampal nitrite content, and decreased antioxidant enzyme levels. TTME administration reduced seizures in a dose-dependent manner and decreased lipid oxidative damage and nitrite-nitrate content, while also restoring enzymatic antioxidant defenses in the hippocampus. TTME also prevented the loss of neuronal cells in the hippocampus region. The study suggests that TTME has anticonvulsant activity and powerful antioxidant potential that can help reduce oxidative stress caused by seizures.

Smilin Bell Aseervatham G et al (2013).
Neurochem Res.
PubMed:
23686347

New cytotoxic cucurbitacins from the pericarps of Trichosanthes tricuspidata fruits.

Mai le P et al (2002).
Nat Prod Lett.
PubMed:
11942676

Cucurbitane, hexanorcucurbitane and octanorcucurbitane glycosides from fruits of Trichosanthes tricuspidata.

Kanchanapoom T, Kasai R and Yamasaki K (2002).
Phytochemistry.
PubMed:
11809458