Urtica dioica

Common Names: California nettle, slender nettle, stinging nettle, tall nettle

Ethnobotanical Studies

Clinical Trials

Comparison of the Effect of Cumin Cyminum and Nettle Oral Drops on the Breast Milk Sufficiency Indicators in New Mothers.

Farshad F et al (2024).
Sultan Qaboos Univ Med J.
DOI:
10.18295/squmj.3.2024.022
PubMed:
38828258

Therapeutic effects of Rosa canina, Urtica dioica and Tanacetum vulgare herbal combination in treatment of tinnitus symptoms: A double-blind randomised clinical trial.

Khosravi MH et al (2023).
Clin Otolaryngol.
DOI:
10.1111/coa.13989
PubMed:
36268807

Urtica Dioica Root Extract on Clinical and Biochemical Parameters in Patients with Benign Prostatic Hyperplasia, Randomized Controlled Trial.

Akbar Karami A et al (2020).
Pak J Biol Sci.
DOI:
10.3923/pjbs.2020.1338.1344
PubMed:
32981268

Studies

LC-MS/MS phenolic profileand remedial role of Urtica dioica extract against Li(2)CO(3)-induced toxicity.

Phytochemistry
Kuloğlu SS, Çavuşoğlu K and Yalçın E (2024).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-024-34791-9
PubMed:
39207615

Gluten-Free Corn Cookies Incorporated With Stinging Nettle Leaf Flour: Effect on Physical Properties, Storage Stability, and Health Benefits.

Tanyitiku MN, Bessem P and Petcheu ICN (2024).
Int J Food Sci.
DOI:
10.1155/2024/8864560
PubMed:
39135739

Total Mineral Content in Raw Materials of Ten Medicinal Plants from Roadside Biotopes of Voronezh Oblast.

Dyakova NA et al (2024).
Dokl Biol Sci.
DOI:
10.1134/S0012496624701126
PubMed:
39128956

Effect of mowing versus abandonment of mesic grasslands in Central Europe on biomass use for biogas production: Implications for semi-natural ecosystem conservation.

Meserszmit M et al (2024).
J Environ Manage.
DOI:
10.1016/j.jenvman.2024.122132
PubMed:
39128343

Ethnobotany around the Virovitica Area in NW Slavonia (Continental Croatia)-Record of Rare Edible Use of Fungus Sarccoscypha coccinea.

Ethnobotany
Vitasović-Kosić I et al (2024).
Plants (Basel).
DOI:
10.3390/plants13152153
PubMed:
39124271

Assessment of Antimicrobial Activity of Chitosan, ZnO, and Urtica dioica-ZnO NPs Against Staphylococcus aureus Isolated from Diabetic Ulcers.

Summary

Survey synthesized chitosan, ZnO, and ZnO-U. dioica nanoparticles to treat antibiotic-resistant S. aureus infections in diabetic ulcers. NPs showed high antibacterial effect and decreased virulence gene expression, making them a potential antimicrobial agent for diabetic ulcers.

AntimicrobialDiabetes
Najafabadi SS et al (2024).
Curr Microbiol.
DOI:
10.1007/s00284-024-03633-9
PubMed:
39096343

Urtica dioica: Anticancer Properties and Other Systemic Health Benefits from In Vitro to Clinical Trials.

Summary

Researchers reviewed the therapeutic benefits of stinging nettle plant for cancer prevention and treatment. It has minimal side effects and potential for various health conditions. Further studies are needed for future research.

Review Cancer
Abi Sleiman M et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25137501
PubMed:
39000608

The impact of mechanical stress on anatomy, morphology, and gene expression in Urtica dioica L.

Summary

Mechanical stress alters leaf anatomy, gene expression, and trichome development in Urtica dioica. Understanding these responses can help improve crop resilience and yield under environmental pressures.

Genetics
Zajączkowska U et al (2024).
Planta.
DOI:
10.1007/s00425-024-04477-0
PubMed:
38970646

Evidence of Urtica dioica Agglutinin's Antiproliferative and Anti-migratory Potentials on the Hyaluronic Acid-Overexpressing Prostate Cancer Cells.

Summary

Plant lectin agglutinin may inhibit tumor progression by targeting hyaluronic acid in prostate cancer cells. It competes with hyaluronic acid for CD44 binding, reducing cell viability and migration. This potential treatment could disrupt the CD44-HA pathway in cancer cells.

Cancer
Heydari M et al (2024).
Planta Med.
DOI:
10.1055/a-2324-2250
PubMed:
38942031

Optimization of Extraction Conditions of Bioactive Compounds From Kurdistan Species Urtica dioica.

Haido MH, Matti AH and Taher SM (2024).
Cureus.
DOI:
10.7759/cureus.61146
PubMed:
38933631

Urtica dioica Extract Abrogates Chlorpyrifos-Induced Toxicity in Zebrafish Larvae.

Mhalhel K et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25126631
PubMed:
38928336

Isolation and characterization of nettle (Urtica dioica L.) seed proteins: Conversion of underutilized by-products of the edible oil industry into food emulsifiers.

Aksoylu Özbek Z et al (2024).
Food Chem.
DOI:
10.1016/j.foodchem.2024.139878
PubMed:
38852455

Potential Anti-Tumorigenic Properties of Diverse Medicinal Plants against the Majority of Common Types of Cancer.

Summary

Study shows natural products from plants have potential in cancer therapy. Phytochemicals regulate molecular pathways, offering chemo-preventive benefits. Literature review highlights medicinal plants' anticancer effects and mechanisms. Important for developing targeted treatments.

Review Cancer
Albahri G et al (2024).
Pharmaceuticals (Basel).
DOI:
10.3390/ph17050574
PubMed:
38794144

Antidiabetic Properties of Caffeoylmalic Acid, a Bioactive Natural Compound Isolated from Urtica dioica.

Summary

Tossers tested caffeoylmalic acid from Urtica dioica for antidiabetic activity. Results showed potential as a novel treatment for type 2 DM, reducing blood glucose levels and improving lipid and blood parameters.

Diabetes
Rehman G et al (2024).
Fitoterapia.
DOI:
10.1016/j.fitote.2024.106024
PubMed:
38763410

Efficacy of an Oral Solution Containing Five Herbal Extracts in the Treatment of Urolithiasis: A Randomized, Single-blind, Placebo-controlled Clinical Trial.

Samandarian S et al (2024).
J Res Pharm Pract.
DOI:
10.4103/jrpp.jrpp_11_24
PubMed:
38716323

Evaluation of Urtica dioica Phytochemicals against Therapeutic Targets of Allergic Rhinitis Using Computational Studies.

Culhuac EB and Bello M (2024).
Molecules.
DOI:
10.3390/molecules29081765
PubMed:
38675586

Biomarker profiling in plants to distinguish between exposure to chlorine gas and bleach using LC-HRMS/MS and chemometrics.

de Bruin-Hoegée M et al (2024).
Forensic Sci Int.
DOI:
10.1016/j.forsciint.2024.112022
PubMed:
38615427

The Influence of Copper and Zinc on Photosynthesis and Phenolic Levels in Basil (Ocimum basilicum L.), Borage (Borago officinalis L.), Common Nettle (Urtica dioica L.) and Peppermint (Mentha piperita L.).

Phytochemistry
Adamczyk-Szabela D and Wolf WM (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25073612
PubMed:
38612424

Potential of Plant-Based Extracts to Alleviate Sorbitol-Induced Osmotic Stress in Cabbage Seedlings.

Pacyga K et al (2024).
Plants (Basel).
DOI:
10.3390/plants13060843
PubMed:
38592867

Impacts of the vegetable Urtica dioica on the intestinal T and B cell phenotype and macronutrient absorption in C57BL/6J mice with diet-induced obesity.

Summary

Including 2% U. dioica in a high-fat diet protects against fat accumulation, insulin resistance, and inflammation in mice. It also enhances immune response and reduces fat and glucose absorption.

GastroenterologyObesity
Fan S et al (2024).
J Nutr Biochem.
DOI:
10.1016/j.jnutbio.2024.109634
PubMed:
38561081

Effects of a proprietary mixture of extracts from Sabal serrulata fruits and Urtica dioica roots (WS(®) 1541) on prostate hyperplasia and inflammation in rats and human cells.

Summary

A study on a plant-based treatment for male lower urinary symptoms showed promising results in rats and human cells, suggesting potential benefits for treating benign prostate syndrome.

Immunology
Sens-Albert C et al (2024).
Front Pharmacol.
DOI:
10.3389/fphar.2024.1379456
PubMed:
38560358

Chemical Constituents of Stinging Nettle (Urtica dioica L.): A Comprehensive Review on Phenolic and Polyphenolic Compounds and Their Bioactivity.

Summary

Stinging nettle is a rich source of polyphenolic compounds with various benefits for food, pharmaceutical, and cosmetic industries. Research aims to summarize its chemical composition and biological activity for potential applications.

Review Phytochemistry
Đurović S et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25063430
PubMed:
38542403

Selective Removal of Chlorophyll and Isolation of Lutein from Plant Extracts Using Magnetic Solid Phase Extraction with Iron Oxide Nanoparticles.

Flieger J et al (2024).
Int J Mol Sci.
DOI:
10.3390/ijms25063152
PubMed:
38542125

The Influence of Urtica dioica and Vitis vinifera Fibers on the Thermal Properties and Flammability of Polylactide Composites.

Majka TM et al (2024).
Materials (Basel).
DOI:
10.3390/ma17061256
PubMed:
38541410

Molecular Docking Analysis of Selected Urtica dioica Constituents As Human Carbonic Anhydrase II (hCA-II), Human 11 Beta-Hydroxysteroid Dehydrogenases Type 1 (h11beta-HSD1), and Human Dual Specificity Phosphatase (hCDC25B) Inhibitory Agents.

Arulselvan AJ, Manimuthu MS and Narayanaswamy R (2024).
Cureus.
DOI:
10.7759/cureus.53886
PubMed:
38465091

Boosting nutritional quality of Urtica dioica L. to resist climate change.

Opačić N et al (2024).
Front Plant Sci.
DOI:
10.3389/fpls.2024.1331327
PubMed:
38425794

Phytotherapy Might Have a Role in Reducing Unnecessary Prostate Biopsies: Results from an Exploratory, Randomized Controlled Trial of Two Different Phytotherapeutic Agents.

Cai T et al (2024).
Clin Pract.
DOI:
10.3390/clinpract14010016
PubMed:
38391402

The role of stinging nettle (Urtica dioica L.) in the management of rotenone-induced Parkinson's disease in rats.

Summary

Stinging Nettle supplement showed neuroprotective effects in a rat model of Parkinson's disease, reducing apoptosis, inflammation, oxidative stress, and improving clearance of alpha-synuclein deposits. Nettle could be a promising treatment for PD.

Neuroscience
Albadawi E et al (2024).
Tissue Cell.
DOI:
10.1016/j.tice.2024.102328
PubMed:
38387425

Investigation of the Antibacterial Properties and Mode of Action of Compounds From Urtica dioica L.

Du J, Fu J and Chen T (2024).
Cureus.
DOI:
10.7759/cureus.52083
PubMed:
38344606

Nanoemulsion and nanoencapsulation of a hydroethanolic extract of Nettle (Urtica dioica) and Wormwood (Artemisia absinthium): comparison of antibacterial and anticancer activity.

Summary

This study investigated the effects of nanoemulsion and nanoencapsulation of Nettle and Wormwood extracts on antibacterial and anticancer activity. The formulations showed increased activity, especially CCNW, making them potentially useful in food and pharmaceutical industries.

Cancer
Rahmani Z et al (2024).
Front Chem.
DOI:
10.3389/fchem.2024.1266573
PubMed:
38292020

Traditional Knowledge Evolution over Half of a Century: Local Herbal Resources and Their Changes in the Upper Susa Valley of Northwest Italy.

Sulaiman N et al (2023).
Plants (Basel).
DOI:
10.3390/plants13010043
PubMed:
38202351

Ethnobotanical and ethnomedicinal research into medicinal plants in the Mt Stara Planina region (south-eastern Serbia, Western Balkans).

Ethnobotany
Jarić S et al (2024).
J Ethnobiol Ethnomed.
DOI:
10.1186/s13002-024-00647-2
PubMed:
38200599

Sono-Microwave Assisted Chlorine free and Ionic Liquid (SMACIL) extraction of cellulose from Urtica dioica: A benign to green approach.

Naseem S et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.129059
PubMed:
38181922

Investigating the phenology and interactions of competitive plant species co-occurring with invasive Lantana camara in Indian Himalayan Region.

Kumar A et al (2024).
Sci Rep.
DOI:
10.1038/s41598-023-50287-x
PubMed:
38172161

Effect of Urtica dioica L. Essential oil (forms of free and nanoliposome) on some inoculated pathogens (Escherichia coli and Listeria monocytogenes) in minced camel meat.

Phytochemistry
Shabani M et al (2023).
Food Chem X.
DOI:
10.1016/j.fochx.2023.101050
PubMed:
38144767

Plants under Siege: Investigating the Relevance of 'Ca. P. solani' Cixiid Vectors through a Multi-Test Study.

Kosovac A et al (2023).
Plants (Basel).
DOI:
10.3390/plants12244157
PubMed:
38140484

Exploring the synergistic potential of wild nettle and olive oil: bioactive compounds, antioxidant capacity, and antibacterial properties.

Summary

This study found that infusing wild nettle leaves with olive oil enhances its nutritional value and health benefits. The infused oil had high levels of antioxidants, antibacterial properties, and increased zinc and iron content. These findings suggest that nettle-infused olive oil could have novel culinary and health applications.

Immunology
Manai-Djebali H et al (2023).
Int J Environ Health Res.
DOI:
10.1080/09603123.2023.2287589
PubMed:
38047414

Protective effects of Urtica dioica on the cerebral cortex damage induced by Potassium bromate in adult male albino rats.

Mahmoud AA, Zayed Mohamed M and Hassen EZ (2023).
Ultrastruct Pathol.
DOI:
10.1080/01913123.2023.2287664
PubMed:
38017656

Protective Effect of Urtica dioica Extract against Oxidative Stress in Human Skin Fibroblasts.

Summary

This study examined the impact of nettle extract on human skin fibroblasts under oxidative stress. The extract showed high antioxidant potential, protecting cells from damage and reducing ROS levels. This suggests that nettle extract could be a beneficial and safe ingredient in skincare products.

Immunology
Skalska-Kamińska A et al (2023).
Life (Basel).
DOI:
10.3390/life13112182
PubMed:
38004322

Prophylactic Coloprotective Effect of Urtica dioica Leaves against Dextran Sulfate Sodium (DSS)-Induced Ulcerative Colitis in Rats.

Summary

An aqueous extract of showed potential in protecting against ulcerative colitis by reducing oxidative stress and inflammation. It contains phenolic compounds that have anti-inflammatory and antioxidant properties. This could be beneficial for treating ulcerative colitis in the future.

Gastroenterology
Dakhli N et al (2023).
Medicina (Kaunas).
DOI:
10.3390/medicina59111990
PubMed:
38004039

Urtica dioica Extract Leads to Cyst Reduction, Enhanced Cell-Mediated Immune Response, and Antioxidant Activity in Experimental Toxoplasmosis.

Immunology
Peyvandi A et al (2023).
Acta Parasitol.
DOI:
10.1007/s11686-023-00727-5
PubMed:
37924457

Effects of algerian nettle (Urtica dioica L.) on benign prostatic hyperplasia and their mechanism of action elucidation: in vivo and in silico approaches.

Bougueroua K et al (2023).
Nat Prod Res.
DOI:
10.1080/14786419.2023.2272283
PubMed:
37867291

Characterization of active films of chitosan containing nettle Urtica dioica L. extract: Spectral and water properties, microstructure, and antioxidant activity.

Immunology
Flórez M, Cazón P and Vázquez M (2023).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.127318
PubMed:
37813218

Identification of novel inhibitors from Urtica spp against TNBC targeting JAK2 receptor for breast cancer therapy.

Summary

Researchers discovered extracts from Urtica dioica and U. parviflora plants containing 12 compounds with better binding energy than Paclitaxel. These extracts showed promising anticancer activity against TNBC cells while being less toxic to healthy cells, hinting at herbal-based drug development for breast cancer.

CancerImmunology
Upreti S et al (2023).
Med Oncol.
DOI:
10.1007/s12032-023-02193-5
PubMed:
37806999

Use of Secondary Metabolites Profiling and Antioxidant Activity to Unravel the Differences between Two Species of Nettle.

Summary

Scientists studied the composition and antioxidant activity of a little-known plant. They optimized enzymatic extraction and analyzed the metabolite profiles using chromatography. The plant showed potential for phytomedicine, with significant differences compared to another species.

Immunology
Baumli J et al (2023).
Plants (Basel).
DOI:
10.3390/plants12183233
PubMed:
37765397

New Insights on Primary and Secondary Metabolite Contents of Seven Italian Wild Food Plants with Medicinal Applications: A Comparative Study.

Monari S et al (2023).
Plants (Basel).
DOI:
10.3390/plants12183180
PubMed:
37765345

Therapeutic Potential of Green-Engineered ZnO Nanoparticles on Rotenone-Exposed D. melanogaster (Oregon R(+)): Unveiling Ameliorated Biochemical, Cellular, and Behavioral Parameters.

Shabir S et al (2023).
Antioxidants (Basel).
DOI:
10.3390/antiox12091679
PubMed:
37759981

Pathophysiology of diabetic hepatopathy and molecular mechanisms underlying the hepatoprotective effects of phytochemicals.

Summary

Herbal extracts like Moringa oleifera and Boswellia serrata have been shown to improve liver function in diabetes. They contain phenolic compounds that protect the liver through various mechanisms, including improving glucose metabolism and antioxidant defense.

Review Diabetes
Mobasheri L et al (2023).
Biomed Pharmacother.
DOI:
10.1016/j.biopha.2023.115502
PubMed:
37734266

Endophytic bacteria isolated from Urtica dioica L.- preliminary screening for enzyme and polyphenols production.

Marchut-Mikołajczyk O et al (2023).
Microb Cell Fact.
DOI:
10.1186/s12934-023-02167-2
PubMed:
37649058

Phytoconstituents from Urtica dioica (stinging nettle) of Sikkim Himalaya and their molecular docking interactions revealed their nutraceutical potential as α-amylase and α-glucosidase inhibitors.

Sharma S et al (2023).
J Food Sci Technol.
DOI:
10.1007/s13197-023-05789-x
PubMed:
37599855

Floristic survey, trace element transfers between soil and vegetation and human health risk at an urban industrial wasteland.

Collot J et al (2023).
J Hazard Mater.
DOI:
10.1016/j.jhazmat.2023.132169
PubMed:
37523956

Bioaccumulation and distribution of Pb, Ni, Zn and Fe in stinging nettle (Urtica dioica) tissues and heavy metal-contamination assessment in the industrial zone of smelter Ferronikeli (Drenas-Kosovo).

Sahiti H et al (2023).
J Environ Sci Health A Tox Hazard Subst Environ Eng.
DOI:
10.1080/10934529.2023.2236535
PubMed:
37463563

Research progress in physiological effects of resistant substances of Urtica dioica L. on animal performance and feed conversion.

Review
Zhang Y et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1164363
PubMed:
37448866

The modulator role of Urtica dioica on deleterious effects of retinoic acid high doses on histological parameters and fertilization of rats.

Du S et al (2023).
Heliyon.
DOI:
10.1016/j.heliyon.2023.e17277
PubMed:
37389058

Urtica dioica Leaf Infusion Enhances the Sensitivity of Triple-Negative Breast Cancer Cells to Cisplatin Treatment.

Summary

A recent study investigated the potential of UD tea in combination with cisplatin as a treatment for breast cancer. The researchers conducted several tests on MDA-MB-231 breast cancer cells and found that the combination significantly reduced cell proliferation compared to each treatment alone. This effect was accompanied by increased signs of apoptosis, including changes in membrane composition and DNA fragmentation. Additionally, the study revealed that the combination increased DNA damage and altered the Bax/Bcl-2 ratio, further supporting the apoptotic mechanism. These findings suggest that UD tea could enhance the effectiveness of cisplatin in treating aggressive breast cancer.

Cancer
Nafeh G et al (2023).
Pharmaceuticals (Basel).
DOI:
10.3390/ph16060780
PubMed:
37375728

Urtica dioica (Gazaneh) distillate restores glucose metabolism in diabetic rats.

Summary

This study investigates the potential antidiabetic effects of on glucose metabolism in diabetic rats. These findings may contribute to improving diabetes treatment strategies.

Diabetes
Zamani-Garmsiri F et al (2023).
Int J Prev Med.
DOI:
10.4103/ijpvm.ijpvm_293_21
PubMed:
37351057

Variation of inflammatory indexes in patients with chronic abacterial prostatitis treated with an herbal compound/extract.

Immunology
Cindolo L et al (2023).
Arch Ital Urol Androl.
DOI:
10.4081/aiua.2023.11441
PubMed:
37314422

Synergistic effect of endurance training and nettle leaf extract on the IDO1-KYN-AHR pathway homeostasis and inhibiting of liver toxicity in rats with STZ-induced diabetes.

Summary

This study investigated the impact of endurance training and nettle leaf extract on liver pathways affected by diabetes in rats.

Diabetes
Haghshenas R et al (2023).
Front Endocrinol (Lausanne).
DOI:
10.3389/fendo.2023.1071424
PubMed:
37305057

Native American ataxia medicines rescue ataxia-linked mutant potassium channel activity via binding to the voltage sensing domain.

Manville RW et al (2023).
Nat Commun.
DOI:
10.1038/s41467-023-38834-6
PubMed:
37280215

Efficacy of a Multicomponent Nutraceutical Formulation for the Prevention and Treatment of Urinary Tract Stones.

Maisto M et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24098316
PubMed:
37176022

The medicinal chemistry of Urtica dioica L.: from preliminary evidence to clinical studies supporting its neuroprotective activity.

Summary

Stinging nettle, a commonly found plant, has been used for various purposes including nutrition, cosmetics, and pharmacology. Its bioactive chemical constituents have been studied for their therapeutic applications. Research shows that compounds found in stinging nettle can provide neuroprotective effects, which could be used to develop tools against neurodegenerative diseases. This review highlights the computational, in vitro, pre-clinical and clinical data supporting the therapeutic applications of stinging nettle and its potential implications for neurodegenerative diseases.

Review Neuroscience
Semwal P et al (2023).
Nat Prod Bioprospect.
DOI:
10.1007/s13659-023-00380-5
PubMed:
37171512

Pain-causing stinging nettle toxins target TMEM233 to modulate Na(V)1.7 function.

Summary

Excelsatoxin A (ExTxA), a plant-derived toxin, interacts with sodium (Na) channels in sensory neurons. TMEM233 is an essential protein for ExTxA's effects on Na channel gating, providing insights into sensory neuron function.

Pain
Jami S et al (2023).
Nat Commun.
DOI:
10.1038/s41467-023-37963-2
PubMed:
37117223

Alpine Diet in Valmalenco (Lombardy, Italy): Nutritional Features of Spontaneous Plants and Traditional Dishes.

Milani F et al (2023).
Nutrients.
DOI:
10.3390/nu15081988
PubMed:
37111208

The Invasive Plant Impatiens glandulifera Manipulates Microbial Associates of Competing Native Species.

Ab Razak N et al (2023).
Plants (Basel).
DOI:
10.3390/plants12071552
PubMed:
37050178

Inhibitory potency of the nettle lectin on neovascularization: a biomolecule for carbohydrate-mediated targeting of angiogenesis.

Samadian E et al (2023).
Mol Biol Rep.
DOI:
10.1007/s11033-023-08355-y
PubMed:
37024746

Chamomile and Urtica dioica extracts improve immunological and histological alterations associated with polycystic ovarian syndrome in DHEA -induced mice.

Summary

This study explores the immune-modulating effects of chamomile and nettle, traditionally used to treat gynecological diseases, in the pathogenesis of Polycystic ovary syndrome (PCOS).

Endocrinology
Shamsi M et al (2023).
BMC Complement Med Ther.
DOI:
10.1186/s12906-023-03936-7
PubMed:
37013510

Stinging Nettle.

Review
(2023).
PubMed:
37011125

Determination of phytochemical content by LC-MS/MS, investigation of antioxidant capacity, and enzyme inhibition effects of nettle (Urtica dioica).

Phytochemistry
Uğur Y and Güzel A (2023).
Eur Rev Med Pharmacol Sci.
DOI:
10.26355/eurrev_202303_31540
PubMed:
36930493

Recovery of Polyphenolic Compounds and Vitamins from the Stinging Nettle Leaves: Thermal and Behavior and Biological Activity of Obtained Extracts.

Phytochemistry
Đurović S et al (2023).
Molecules.
DOI:
10.3390/molecules28052278
PubMed:
36903524

Apoptotic, cytotoxic, antioxidant, and antibacterial activities of biosynthesized silver nanoparticles from nettle leaf.

Dağlıoğlu Y, Öztürk BY and Khatami M (2023).
Microsc Res Tech.
DOI:
10.1002/jemt.24306
PubMed:
36883432

Nettle (Urtica dioica) Additive as a Growth Promoter and Immune Stimulator in Fish.

Review
Zare M et al (2023).
Aquac Nutr.
DOI:
10.1155/2023/8261473
PubMed:
36864904

Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction.

Đurović S et al (2023).
Foods.
DOI:
10.3390/foods12040809
PubMed:
36832884

Edible wild plant species used by different linguistic groups of Kohistan Upper Khyber Pakhtunkhwa (KP), Pakistan.

Amin M et al (2023).
J Ethnobiol Ethnomed.
DOI:
10.1186/s13002-023-00577-5
PubMed:
36782205

Vertical Columns with Sustainable Green Cover: Meadow Plants in Urban Design.

Stakelienė V et al (2023).
Plants (Basel).
DOI:
10.3390/plants12030636
PubMed:
36771721

Copper Uptake and Its Effects on Two Riparian Plant Species, the Native Urtica dioica, and the Invasive Fallopia japonica.

Schmitz D et al (2023).
Plants (Basel).
DOI:
10.3390/plants12030481
PubMed:
36771566

Urtica dioica agglutinin (UDA) as a potential candidate for inhibition of SARS-CoV-2 Omicron variants: In silico prediction and experimental validation.

Summary

Researchers studied the effectiveness of a plant-derived protein called Urtica dioica agglutinin (UDA) in blocking the Receptor Binding Domain (RBD) of the Omicron variant of SARS-CoV-2. The RBD has many mutations, which may make it more resistant to antibodies from previous infections or vaccinations. Since UDA has shown antiviral activity against SARS-CoV-2, it might be a useful drug for treating this highly transmissible variant.

COVID-19
Sabzian-Molaei F et al (2023).
Phytomedicine.
DOI:
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