Vaccinium arctostaphylos

Ethnobotanical Studies

Clinical Trials

Efficacy and Safety of a Traditional Herbal Combination in Patients with Type II Diabetes Mellitus: A Randomized Controlled Trial.

This study examines the effectiveness and safety of a traditional herbal combination used for treating diabetes in Iran, which lacks controlled human evidence.

Mehrzadi S et al (2021).
J Diet Suppl.
DOI:
10.1080/19390211.2020.1727076
PubMed:
32081056

Antihypertensive efficacy and safety of Vaccinium arctostaphylos berry extract in overweight/obese hypertensive patients: A randomized, double-blind and placebo-controlled clinical trial.

This study investigated the effectiveness and safety of a particular extract from V. arctostaphylos berries in treating hypertension in overweight/obese patients.

Kianbakht S and Hashem-Dabaghian F (2019).
Complement Ther Med.
DOI:
10.1016/j.ctim.2019.05.010
PubMed:
31126570

Controlling type 2 diabetes mellitus with herbal medicines: A triple-blind randomized clinical trial of efficacy and safety.

Mirfeizi M et al (2016).
J Diabetes.
DOI:
10.1111/1753-0407.12342
PubMed:
26362826

Studies

The Potential Hepatoprotective Effect of Vaccinium arctostaphylos L. Fruit Extract in Diabetic Rat.

Summary

Researchers investigated the effects of arctostaphylos fruit extract on diabetic rats' livers. Understanding its molecular mechanisms could help enhance the treatment of diabetes.

Diabetes
Saliani N, Montasser Kouhsari S and Izad M (2023).
Cell J.
DOI:
10.22074/cellj.2023.2004742.1328
PubMed:
37865880

Caucasian Blueberry: Comparative Study of Phenolic Compounds and Neuroprotective and Antioxidant Potential of Vaccinium myrtillus and Vaccinium arctostaphylos Leaves.

Summary

Leaf extracts of two Caucasian blueberry bushes, L. and L., were analyzed for phenolic compounds and their potential neurotropic effects were studied. Hydroxycinnamates and flavonoids were identified, with 5-caffeoylquinic acid being the dominant metabolite. The extracts improved cerebral hemodynamics, reduced brain tissue necrosis, and increased antioxidant enzyme activity. The study suggests that the extracts can be used as therapeutic agents in treating neurological diseases.

NeurosciencePhytochemistry
Shamilov AA et al (2022).
Life (Basel).
DOI:
10.3390/life12122079
PubMed:
36556444

Biogenic and facile synthesis of selenium nanoparticles using Vaccinium arctostaphylos L. fruit extract and anticancer activity against in vitro model of breast cancer.

Cancer
Gharbavi M et al (2022).
Cell Biol Int.
DOI:
10.1002/cbin.11852
PubMed:
35819083

Investigating the Possibility of Green Synthesis of Silver Nanoparticles Using Vaccinium arctostaphlyos Extract and Evaluating Its Antibacterial Properties.

Khodadadi S et al (2021).
Biomed Res Int.
DOI:
10.1155/2021/5572252
PubMed:
33997013

The effects of hydroalcoholic extract of Vaccinium arctostaphylos L. on sperm parameters, oxidative injury and apoptotic changes in oxymetholone-induced testicular toxicity in mouse.

Akbari Bazm M et al (2020).
Andrologia.
DOI:
10.1111/and.13522
PubMed:
32012329

A facile ultrasonic-aided biosynthesis of ZnO nanoparticles using Vaccinium arctostaphylos L. leaf extract and its antidiabetic, antibacterial, and oxidative activity evaluation.

Diabetes
Bayrami A et al (2019).
Ultrason Sonochem.
DOI:
10.1016/j.ultsonch.2019.03.010
PubMed:
31084791

Purification and characterization of glutathione S-transferase from blueberry fruits (Vaccinium arctostaphylos L.) and investigated of some pesticide inhibition effects on enzyme activity.

Balcı N et al (2019).
Heliyon.
DOI:
10.1016/j.heliyon.2019.e01422
PubMed:
31011639

Hepatoprotective effects of Vaccinium arctostaphylos against CCl4-induced acute liver injury in rats.

Ravan AP et al (2017).
J Basic Clin Physiol Pharmacol.
DOI:
10.1515/jbcpp-2016-0181
PubMed:
28467312

Evaluation of the Effects of Vaccinium arctostaphylos L. Fruit Extract on Serum Lipids and hs-CRP Levels and Oxidative Stress in Adult Patients with Hyperlipidemia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Soltani R et al (2014).
Evid Based Complement Alternat Med.
DOI:
10.1155/2014/217451
PubMed:
24587807

Vaccinium arctostaphylos, a common herbal medicine in Iran: molecular and biochemical study of its antidiabetic effects on alloxan-diabetic Wistar rats.

Diabetes
Feshani AM, Kouhsari SM and Mohammadi S (2011).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2010.09.002
PubMed:
20850514

Characterization of anthocyanins in caucasian blueberries (Vaccinium arctostaphylos L.) native to Turkey.

Lätti AK et al (2009).
J Agric Food Chem.
DOI:
10.1021/jf9005627
PubMed:
19480388