Valeriana jatamansi

Ethnobotanical Studies

Gelao ethnic minority, North Guizhou, China

Uses: Stomach disease

DOI:: 10.3389/fphar.2023.1217599
PubMed:: 37719846

Yi people, Mile, Yunnan, China

Uses: Dyspepsia, irregular menstruation

DOI:: 10.1186/s13002-024-00656-1
PubMed:: 38395900

Gaoligongshan area, Western Yunnan, Southwest China

Uses: Abdominal pain, diarrhea, dyspepsia, rheumatism, soreness and weakness of waist and knees, insomnia

DOI:: 10.1186/s13002-023-00638-9
PubMed:: 38225656

Studies

Unveiling the potential of native arbuscular mycorrhizal fungi for growth promotion and phytochemical enrichment in Valeriana jatamansi Jones.

Phytochemistry

Tapwal A et al (2024).; Int Microbiol.
DOI:: 10.1007/s10123-024-00548-0
PubMed:: 38951390

Research progress in the ethnopharmacology, phytochemistry, pharmacology, toxicology, and quality control of Valeriana jatamansi Jones.

Summary

Valeriana jatamansi herb has historical medicinal use in TCM and Ayurveda, with modern research showing potential benefits for nervous and digestive systems. Important for lab research.

Review Phytochemistry

Wang Z et al (2024).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2024.118403
PubMed:: 38821137

Essential Oil Constituents as Anti-Inflammatory and Neuroprotective Agents: An Insight through Microglia Modulation.

Summary

This study explores how essential oils can regulate microglial function to potentially mitigate neuroinflammation and neurodegeneration. They suggest that certain components of essential oils may target specific signaling pathways involved in inflammation, offering a potential therapeutic approach for treating neurodegenerative diseases.

Review Immunology Neuroscience Phytochemistry

Stojanović NM et al (2024).; Int J Mol Sci.
DOI:: 10.3390/ijms25105168
PubMed:: 38791205

Iridoids rich fraction from Valeriana jatamansi Jones promotes axonal regeneration and motor functional recovery after spinal cord injury through activation of the PI3K/Akt signaling pathway.

Wang Y et al (2024).; Front Mol Neurosci.
DOI:: 10.3389/fnmol.2024.1400927
PubMed:: 38756705

Physiological and biochemical regulation of Valeriana jatamansi Jones under water stress.

Thakur A et al (2024).; Plant Physiol Biochem.
DOI:: 10.1016/j.plaphy.2024.108476
PubMed:: 38442628

Corrigendum to: Valeriana jatamansi Jones Inhibits Rotavirus-Induced Diarrhea via Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling Pathway.

Zhang B et al (2024).; J Microbiol Biotechnol.
DOI:: 10.4014/jmb.2024.3402.484
PubMed:: 38419325

Valeriana jatamansi: Bioactive Compounds and their Medicinal Uses.

Maurya AK and Agnihotri VK (2024).; Curr Top Med Chem.
DOI:: 10.2174/0115680266273617240129042653
PubMed:: 38318825

Eighteen iridoids from the roots and rhizomes of Valeriana jatamansi and their protective effects against α-hemolysin.

Zhu Y et al (2024).; Phytochemistry.
DOI:: 10.1016/j.phytochem.2023.113962
PubMed:: 38185394

Mechanism of Valeriana Jatamansi Jones for the treatment of spinal cord injury based on network pharmacology and molecular docking.

Wang Y et al (2023).; Medicine (Baltimore).
DOI:: 10.1097/MD.0000000000036434
PubMed:: 38115366

10.

Simultaneously characterization of multiple constituents in Valeriana jatamansi Jones using an online supercritical fluid extraction-high-performance liquid chromatography/supercritical fluid chromatography-mass spectrometry system.

Phytochemistry

Chen H et al (2023).; J Sep Sci.
DOI:: 10.1002/jssc.202300550
PubMed:: 38066382

11.

Neurological potency of native plants from sub-Himalayan West Bengal through reverse pharmacology.

Tshering Dhendup L et al (2023).; Bioinformation.
DOI:: 10.6026/97320630019995
PubMed:: 37969663

12.

Complete genome sequence analysis of Valeriana jatamansi tymovirus 1: a novel member of the genus Tymovirus infecting Valeriana jatamansi Jones.

Genetics

Chu B et al (2023).; Arch Virol.
DOI:: 10.1007/s00705-023-05876-6
PubMed:: 37676512

13.

A comprehensive overview of breeding strategy to improve phenotypic and quality traits in Valeriana jatamansi Jones.

Review

Gautam RD et al (2023).; Heliyon.
DOI:: 10.1016/j.heliyon.2023.e18294
PubMed:: 37560641

14.

Therapeutic Effects of Valeriana jatamansi on Ulcerative Colitis: Insights into Mechanisms of Action through Metabolomics and Microbiome Analysis.

Gastroenterology

Wang L et al (2023).; J Proteome Res.
DOI:: 10.1021/acs.jproteome.3c00237
PubMed:: 37475705

15.

11-Ethoxyviburtinal improves chronic restraint stress-induced anxiety-like behaviors in gender-specific mice via PI3K/Akt and E(2) /ERβ signaling pathways.

Neuroscience

Lyu Y et al (2023).; Phytother Res.
DOI:: 10.1002/ptr.7876
PubMed:: 37300355

16.

Comparative assessment of morphological, physiological and phytochemical attributes of cultivated Valeriana jatamansi Jones in Uttarakhand, West Himalaya.

Phytochemistry

Bahukhandi A et al (2023).; Plant Physiol Biochem.
DOI:: 10.1016/j.plaphy.2023.107751
PubMed:: 37230025

17.

A new iridoid from the roots of Valeriana jatamansi Jones with α-glucosidase activity.

Maurya AK and Agnihotri VK (2023).; Nat Prod Res.
DOI:: 10.1080/14786419.2023.2187796
PubMed:: 36890769

18.

Lignans from the root of Valeriana jatamansi and their biological evaluation.

Phytochemistry

Tan YZ et al (2023).; J Asian Nat Prod Res.
DOI:: 10.1080/10286020.2022.2145958
PubMed:: 36394297

19.

Antidiarrheal activity of the extracts of Valeriana jatamansi Jones on castor oil-induced diarrhea mouse by regulating multiple signal pathways.

Ma YL et al (2022).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2022.115560
PubMed:: 35863616

20.

Chemical profiling and α-glucosidase inhibitory activity of essential oils extracted with two methods from some North Western Himalayan aromatic crops.

Phytochemistry

Maurya AK, Devi K and Agnihotri VK (2023).; Nat Prod Res.
DOI:: 10.1080/14786419.2022.2069108
PubMed:: 35481430

21.

Secondary metabolites from Valeriana jatamansi with their anti-inflammatory activity.

Immunology

Tram LH et al (2022).; Nat Prod Res.
DOI:: 10.1080/14786419.2021.2004600
PubMed:: 34812687

22.

A new acylated iridoid and other chemical constituents from Valeriana jatamansi and their biological activities.

Wang Y et al (2023).; Nat Prod Res.
DOI:: 10.1080/14786419.2021.1961255
PubMed:: 34343061

23.

Antidepressant effects of total iridoids of Valeriana jatamansi via the intestinal flora-blood-brain barrier pathway.

Gastroenterology Neuroscience

Zhang L et al (2021).; Pharm Biol.
DOI:: 10.1080/13880209.2021.1944222
PubMed:: 34236293

24.

New iridoids from the roots of Valeriana jatamansi Jones.

Maurya AK, Kumar A and Agnihotri VK (2022).; Nat Prod Res.
DOI:: 10.1080/14786419.2020.1858412
PubMed:: 33297740

25.

Suppression of the USP10/CCND1 axis induces glioblastoma cell apoptosis.

Sun T et al (2021).; Acta Pharmacol Sin.
DOI:: 10.1038/s41401-020-00551-x
PubMed:: 33184448

26.

Valeriana jatamansi Jones Inhibits Rotavirus-Induced Diarrhea via Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling Pathway.

Zhang B et al (2021).; J Microbiol Biotechnol.
DOI:: 10.4014/jmb.2003.03006
PubMed:: 32522968

27.

Bioactive 3,8-Epoxy Iridoids from Valeriana jatamansi.

Quan LQ et al (2019).; Chem Biodivers.
DOI:: 10.1002/cbdv.201800474
PubMed:: 30801931

28.

Valeriana jatamansi: An herbaceous plant with multiple medicinal uses.

Review

Jugran AK et al (2019).; Phytother Res.
DOI:: 10.1002/ptr.6245
PubMed:: 30663144

29.

Three minor valepotriate isomers from Valeriana jatamansi and their cytotoxicity.

Lin S et al (2017).; J Asian Nat Prod Res.
DOI:: 10.1080/10286020.2016.1258065
PubMed:: 27924641

30.

Iridoids from the roots of Valeriana jatamansi.

Xu J et al (2012).; J Asian Nat Prod Res.
DOI:: 10.1080/10286020.2011.618804
PubMed:: 22263587