Verbascum thapsus

Common Names: flannel mullein, great mullein, mullein, big taper, flannel plant, velvet dock, velvet plant, woolly mullein, common mullein

Ethnobotanical Studies

Central Europe

DOI:: 10.3390/plants12010135
PubMed:: 36616265

Viesca and Parras Coahuila, northeast Mexico

Uses: Respiratory system diseases

DOI:: 10.1016/j.jsps.2022.11.003
PubMed:: 36685306

Boreal Forest, Canada

Uses: Dermatological infections, Injuries, Odontological problems, Respiratory system disorders

DOI:: 10.1186/1746-4269-8-7
PubMed:: 22289509

Clinical Trials

The effect of the Verbascum Thapsus on episiotomy wound healing in nulliparous women: a randomized controlled trial.

Taleb S and Saeedi M (2021).; BMC Complement Med Ther.
DOI:: 10.1186/s12906-021-03339-6
PubMed:: 34103042

Studies

Bioassay-guided fractionation of Verbascum thapsus extract and its combination with polyvinyl alcohol in the form electrospun nanofibrous membrane for efficient wound dressing application.

Razani S et al (2024).; Heliyon.
DOI:: 10.1016/j.heliyon.2024.e32717
PubMed:: 39183880

Modulation of innate immunity related genes resulting in prophylactic antimicrobial and antiviral properties.

Summary

Researchers studied how interactions between viruses (influenza, RSV) and bacteria/fungi in the respiratory tract can dysregulate the immune system during COVID-19, especially in children and vulnerable populations. This knowledge is crucial for managing co-infections and improving patient outcomes.

Antimicrobial Genetics

Ferrucci V et al (2024).; J Transl Med.
DOI:: 10.1186/s12967-024-05378-2
PubMed:: 38886736

Clean synthesis of silver nanoparticles (AgNPs) on polyamide fabrics by Verbascum thapsus L. (mullein) extract: characterization, colorimetric, antibacterial, and colorfastness studies.

Sadeghi-Kiakhani M, Hashemi E and Norouzi MM (2024).; Environ Sci Pollut Res Int.
DOI:: 10.1007/s11356-024-33373-z
PubMed:: 38658510

Antioxidant, AChE inhibitory, and anticancer effects of Verbascum thapsus extract.

Summary

In this study, the researchers investigated the biological functions of Verbascum thapsus methanol extract. They used chromatography and spectrometry to analyze its composition, and tested its antioxidant capacity and cytotoxicity on different cell lines. The extract showed low antioxidant activity but inhibited acetylcholinesterase enzyme.

Cancer Immunology

Zhang N et al (2023).; Cell Mol Biol (Noisy-le-grand).
DOI:: 10.14715/cmb/2023.69.14.35
PubMed:: 38279434

Alternative Crops for the European Tobacco Industry: A Systematic Review.

Review

Mavroeidis A et al (2024).; Plants (Basel).
DOI:: 10.3390/plants13020236
PubMed:: 38256796

Mercury distribution in plants and soils from the former mining area of Abbadia San Salvatore (Tuscany, Central Italy).

Meloni F et al (2023).; Environ Geochem Health.
DOI:: 10.1007/s10653-023-01739-w
PubMed:: 37648955

A cross-cultural study of high-altitude botanical resources among diverse ethnic groups in Kashmir Himalaya, India.

Haq SM et al (2023).; J Ethnobiol Ethnomed.
DOI:: 10.1186/s13002-023-00582-8
PubMed:: 37055855

The Complete Genome Sequence of Verbascum thapsus (Scrophulariaceae, Lamiales), the Common Mullein.

Genetics

Badad O et al (2023).; Biodivers Genomes.
DOI:: 10.56179/001c.73050
PubMed:: 37009556

Dietary Supplementation with Boswellia serrata, Verbascum thapsus, and Curcuma longa in Show Jumping Horses: Effects on Serum Proteome, Antioxidant Status, and Anti-Inflammatory Gene Expression.

Genetics Immunology

Beghelli D et al (2023).; Life (Basel).
DOI:: 10.3390/life13030750
PubMed:: 36983904

10.

Gold Nanoparticles Synthesized with Common Mullein (Verbascum thapsus) and Castor Bean (Ricinus communis) Ethanolic Extracts Displayed Antiproliferative Effects and Induced Caspase 3 Activity in Human HT29 and SW480 Cancer Cells.

Cancer

Soto KM et al (2022).; Pharmaceutics.
DOI:: 10.3390/pharmaceutics14102069
PubMed:: 36297503

11.

Phytoremediation of toxic heavy metals in polluted soils and water of Dargai District Malakand Khyber Pakhtunkhwa, Pakistan.

Khan Q et al (2022).; Braz J Biol.
DOI:: 10.1590/1519-6984.265278
PubMed:: 36228229

12.

The complete chloroplast genome of Verbascum thapsus L. (Scrophulariaceae) and its phylogenetic affinities.

Genetics

Zhang Y et al (2022).; Mitochondrial DNA B Resour.
DOI:: 10.1080/23802359.2022.2113749
PubMed:: 36082042

13.

Viability of Wildflower Seeds After Mesophilic Anaerobic Digestion in Lab-Scale Biogas Reactors.

Hahn J et al (2022).; Front Plant Sci.
DOI:: 10.3389/fpls.2022.942346
PubMed:: 35909787

14.

Self-Medication Practice in Mexico.

Ortiz MI, Flores-Ceron KI and Muñoz-Pérez VM (2022).; Sr Care Pharm.
DOI:: 10.4140/TCP.n.2022.266
PubMed:: 35752917

15.

Using Autumnal Trap Crops to Manage Tarnished Plant Bugs (Lygus lineolaris).

Dumont F and Provost C (2022).; Insects.
DOI:: 10.3390/insects13050441
PubMed:: 35621777

16.

Ultrasound Assisted Extraction and Characterization of Bioactives From Verbascum thapsus Roots to Evaluate Their Antioxidant and Medicinal Potential.

Shahbaz F et al (2022).; Dose Response.
DOI:: 10.1177/15593258221097665
PubMed:: 35529303

17.

Health-promoting and disease-mitigating potential of Verbascum thapsus L. (common mullein): A review.

Review

Gupta A et al (2022).; Phytother Res.
DOI:: 10.1002/ptr.7393
PubMed:: 35088467

18.

Phytochemical Analysis and Anti-Inflammatory and Anti-Osteoarthritic Bioactive Potential of Verbascum thapsus L. (Scrophulariaceae) Leaf Extract Evaluated in Two In Vitro Models of Inflammation and Osteoarthritis.

Immunology Phytochemistry

Calabrese G et al (2021).; Molecules.
DOI:: 10.3390/molecules26175392
PubMed:: 34500824

19.

Safety of a feed additive consisting of a tincture derived from Verbascum thapsus L. (great mullein tincture) for use in all animal species (MANGHEBATI SAS).

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) et al (2021).; EFSA J.
DOI:: 10.2903/j.efsa.2021.6711
PubMed:: 34335922

20.

Influence of soil pollution on the morphology of roots and leaves of Verbascum thapsus L.

Chaplygin V et al (2022).; Environ Geochem Health.
DOI:: 10.1007/s10653-021-00975-2
PubMed:: 34050848

21.

Safety and efficacy of a tincture derived from Verbascum thapsus L. when used as a sensory additive in feed for all animal species.

EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) et al (2019).; EFSA J.
DOI:: 10.2903/j.efsa.2019.5910
PubMed:: 32626200

22.

The Antioxidant, Anticarcinogenic and Antimicrobial Properties of Verbascum thapsus L.

Antimicrobial

Mahdavi S et al (2020).; Med Chem.
DOI:: 10.2174/1573406415666190828155951
PubMed:: 31456524

23.

Do recent research studies validate the medicinal plants used in British Columbia, Canada for pet diseases and wild animals taken into temporary care?

Review

Lans C et al (2019).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2019.02.030
PubMed:: 30772483

24.

Effect of Verbascum thapsus ethanol extract on induction of apoptosis in Trichomonas vaginalis in vitro.

Kashan ZF et al (2015).; Infect Disord Drug Targets.
PubMed:: 26239850

25.

Common mullein (Verbascum thapsus L.): recent advances in research.

Review

Turker AU and Gurel E (2005).; Phytother Res.
PubMed:: 16222647