Verbena officinalis

Common Names: herb of the cross

Ethnobotanical Studies

Studies

Luteolin-7-diglucuronide, a novel PTP1B inhibitor, ameliorates hepatic stellate cell activation and liver fibrosis in mice.

Tang BX et al (2024).
Acta Pharmacol Sin.
DOI:
10.1038/s41401-024-01351-3
PubMed:
39103531

Verbena officinalis (VO) leaf extract as an anti-corrosion inhibitor for carbon steel in acidic environment.

Fouda AES et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-65266-z
PubMed:
38997319

Study on fingerprint and quantitative analysis of Verbena officinalis water extract by LC-MS and HPLC.

Feng R et al (2024).
Biomed Chromatogr.
DOI:
10.1002/bmc.5894
PubMed:
38777624

Ethanol extract of Verbena officinalis alleviates MCAO-induced ischaemic stroke by inhibiting IL17A pathway-regulated neuroinflammation.

Summary

Researchers investigated the therapeutic potential of Verbena officinalis in managing ischaemic stroke. Significant neuroprotective effects were observed, but further research is needed to understand the bioactive compounds and mechanisms involved. This study may offer insights for developing new treatment strategies.

CardiologyNeuroscience
Zhang W et al (2023).
Phytomedicine.
DOI:
10.1016/j.phymed.2023.155237
PubMed:
38056148

Plant Extracts as Skin Care and Therapeutic Agents.

Review
Michalak M et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms242015444
PubMed:
37895122

Characterization and bioactivities of M. arvensis, V. officinalis and P. glabrum: In-silico modeling of V. officinalis as a potential drug source.

Shah SAA et al (2023).
Saudi J Biol Sci.
DOI:
10.1016/j.sjbs.2023.103646
PubMed:
37181636

Bioactive Constituents of Verbena officinalis Alleviate Inflammation and Enhance Killing Efficiency of Natural Killer Cells.

Immunology
Dai X et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms24087144
PubMed:
37108306

Key ingredients in Verbena officinalis and determination of their anti-atherosclerotic effect using a computer-aided drug design approach.

Chen Y et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1154266
PubMed:
37077636

Verbenalin attenuates hepatic damage and mitochondrial dysfunction in alcohol-associated steatohepatitis by regulating MDMX/PPARα-mediated ferroptosis.

Dong J et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.116227
PubMed:
36739928

Hastatoside attenuatescarbon tetrachloride-induced liver fibrosis by targeting glycogen synthase kinase-3β.

Du C et al (2023).
Phytomedicine.
DOI:
10.1016/j.phymed.2022.154585
PubMed:
36610117

Verbenalin Reduces Amyloid-Beta Peptide Generation in Cellular and Animal Models of Alzheimer's Disease.

Summary

Verbenalin, found in a medicinal plant, has been shown to reduce the production of amyloid-beta (Aβ) peptide in Alzheimer's disease (AD) animal models. In vitro and in vivo experiments displayed decreased levels of Aβ and tau expression in animals treated with verbenalin. Additionally, verbenalin restored the expression of brain-derived neurotrophic factor (BDNF) in the hippocampus, suggesting it may improve the pathological hallmarks of AD. The findings propose that verbenalin can decrease Aβ formation and aid in treating AD.

Neuroscience
Lim J et al (2022).
Molecules.
DOI:
10.3390/molecules27248678
PubMed:
36557811

Exercise Training and Verbena officinalis L. Affect Pre-Clinical and Histological Parameters.

Rodrigues Oliveira SM et al (2022).
Plants (Basel).
DOI:
10.3390/plants11223115
PubMed:
36432843

Chemical Composition and Antioxidant Properties of Common and Lemon Verbena.

Polumackanycz M et al (2022).
Antioxidants (Basel).
DOI:
10.3390/antiox11112247
PubMed:
36421433

Cornin protects against cerebral ischemia/reperfusion injury by preventing autophagy via the PI3K/Akt/mTOR pathway.

Cardiology
Lan T et al (2022).
BMC Pharmacol Toxicol.
DOI:
10.1186/s40360-022-00620-3
PubMed:
36280856

Metabolic Profiling by GC-MS, In Vitro Biological Potential, and In Silico Molecular Docking Studies of Verbena officinalis.

Nisar R et al (2022).
Molecules.
DOI:
10.3390/molecules27196685
PubMed:
36235221

Integrating transcriptome and chemical analyses to reveal the anti-Alzheimer's disease components in Verbena officinalis Linn.

Summary

A study found that Linn., an herb in Chinese medicine, contains compounds that exhibit anti-Alzheimer's disease (AD) activity. The main chemical components were identified through ultra-performance liquid chromatography-mass spectrometry and subsequently used for molecular docking. The transcriptome analysis revealed that leaves had relatively high expression of the anti-AD compounds, and transcription factors may be involved in their biosynthesis. The study provides insights into the biosynthetic pathway of anti-AD components and the regulation mechanism of active components and furthers the potential of Linn. as a treatment for AD.

GeneticsNeuroscience
Peng S et al (2022).
Front Plant Sci.
DOI:
10.3389/fpls.2022.955075
PubMed:
35991454

Poly(vinyl alcohol)/Plant Extracts Films: Preparation, Surface Characterization and Antibacterial Studies against Gram Positive and Gram Negative Bacteria.

Barbălată-Mândru M et al (2022).
Materials (Basel).
DOI:
10.3390/ma15072493
PubMed:
35407829

Characterization of the chloroplast genome of Verbena officinalis Linn. (Verbenaceae) and its phylogenetic analysis.

Genetics
Fang Z et al (2021).
Mitochondrial DNA B Resour.
DOI:
10.1080/23802359.2021.1914224
PubMed:
34104747

Verbena officinalis Verbenaceae (Lamiales): a new plant model system for phyllotaxis research.

Zagórska-Marek B, Turzańska M and Chmiel K (2021).
J Plant Res.
DOI:
10.1007/s10265-021-01288-2
PubMed:
33830395

Verbena officinalis (Common Vervain) - A Review on the Investigations of This Medicinally Important Plant Species.

Review
Kubica P et al (2020).
Planta Med.
DOI:
10.1055/a-1232-5758
PubMed:
32937665

Vervain.

Review
(2021).
PubMed:
30000912