Vinca minor

Common Names: common periwinkle, lesser periwinkle, myrtle

Ethnobotanical Studies

Studies

Demonstration of the Protective Effect of Vinpocetine in Diabetic Cardiomyopathy.

Summary

Study on Vinpocetine's effects on diabetic cardiomyopathy showed it reduced heart damage, improved markers and structure. Vinpocetine may be a promising treatment for diabetic heart disease.

CardiologyDiabetes
Erciyes D et al (2024).
J Clin Med.
DOI:
10.3390/jcm13164637
PubMed:
39200779

Vincamine exerts hepato-protective activity during colon ligation puncture-induced sepsis by modulating oxidative stress, apoptosis, and TNFα/Nrf-2/Keap-1 signaling pathways.

Summary

Vincamine protects the liver during sepsis by reducing liver enzymes, oxidative stress, inflammation, and apoptosis. It modulates key pathways to improve liver function.

GastroenterologyImmunology
Alaaeldin R et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-69729-1
PubMed:
39174578

Development of New Dermato-Cosmetic Therapeutic Formulas with Extracts of Vinca minor L. Plants from the Dobrogea Region.

Neculai AM et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms242216234
PubMed:
38003424

Comparative polyphenolic profiling of five ethnomedicinal plants and their applicative potential in the treatment of type 2 diabetes.

Summary

These plants have been traditionally used for preventing and treating diseases like diabetes. They may contain beneficial compounds that could be useful for developing new treatments in the lab.

DiabetesEthnobotany
Kukavica B et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117377
PubMed:
37939910

Determination of Active Ingredients, Mineral Composition and Antioxidant Properties of Hydroalcoholic Macerates of Vinca minor L. Plant from the Dobrogea Area.

Summary

This study analyzed the chemical and mineral composition of Vinca plant for use in dermal preparations. It found high concentrations of the bioactive compound vincamine and antioxidant activity. The plant also had low levels of toxic metals.

Immunology
Neculai AM, Stanciu G and Mititelu M (2023).
Molecules.
DOI:
10.3390/molecules28155667
PubMed:
37570636

Genomic and Metabolomic Analysis of the Endophytic Fungus Fusarium sp. VM-40 Isolated from the Medicinal Plant Vinca minor.

He T et al (2023).
J Fungi (Basel).
DOI:
10.3390/jof9070704
PubMed:
37504693

Vincamine Ameliorates Epithelial-Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis in Rats; Targeting TGF-β/MAPK/Snai1 Pathway.

Immunology
Alaaeldin R et al (2023).
Molecules.
DOI:
10.3390/molecules28124665
PubMed:
37375218

Disease-Modifying Effects of Vincamine Supplementation in Drosophila and Human Cell Models of Parkinson's Disease Based on DJ-1 Deficiency.

Summary

Researchers found that a natural compound called vincamine showed promise in treating Parkinson's disease by improving motor ability in a fly model and reducing oxidative stress-induced death in human cells. Vincamine was shown to suppress PD-related symptoms and increased mitochondrial viability while decreasing apoptosis in human cells. The study also suggested that targeting voltage-gated sodium channels may be a promising avenue for treating PD.

Neuroscience
Sanz FJ, Solana-Manrique C and Paricio N (2023).
ACS Chem Neurosci.
DOI:
10.1021/acschemneuro.3c00026
PubMed:
37289979

Flowers and Inflorescences of Selected Medicinal Plants as a Source of Triterpenoids and Phytosterols.

Edorh Tossa P et al (2023).
Plants (Basel).
DOI:
10.3390/plants12091838
PubMed:
37176893

Bio-evaluation of untapped alkaloids from Vinca minor enriched by methyl jasmonate induced stress: An Integrated approach.

Phytochemistry
El-Senduny FF et al (2023).
Planta Med.
DOI:
10.1055/a-2058-3863
PubMed:
36940927

Assessment of plant species suitability in green walls based on API, heavy metal accumulation, and particulate matter capture capacity.

Hozhabralsadat MS et al (2022).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-022-20625-z
PubMed:
35545746

Whole-Genome Characterization of Alfalfa Mosaic Virus Obtained from Metagenomic Analysis of Vinca minor and Wisteria sinensis in Iran: with Implications for the Genetic Structure of the Virus.

Genetics
Moradi Z and Mehrvar M (2022).
Plant Pathol J.
DOI:
10.5423/PPJ.ER.10.2021.0151
PubMed:
35144362

Building a Barrier: The Influence of Different Wax Fractions on the Water Transpiration Barrier of Leaf Cuticles.

Seufert P et al (2022).
Front Plant Sci.
DOI:
10.3389/fpls.2021.766602
PubMed:
35069622

Fluorometric quantification of alkaloids in the homeopathic mother tinctures of Vinca minor L. and Fumaria officinalis L.

Phytochemistry
Sehner SM and Melzig MF (2022).
Pharmazie.
DOI:
10.1691/ph.2022.1135
PubMed:
35045917

Whole-Genome Characterization of Alfalfa Mosaic Virus Obtained from Metagenomic Analysis of Vinca minor and Wisteria sinensis in Iran: with Implications for the Genetic Structure of the Virus.

Genetics
Moradi Z and Mehrvar M (2021).
Plant Pathol J.
DOI:
10.5423/PPJ.OA.10.2021.0151
PubMed:
34897253

Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): Identification of new structural scaffold for treatment of Alzheimer's disease.

Summary

Researchers identified a previously unknown indole alkaloid and 22 known compounds in Vinca minor L. plants using a range of analytical techniques. They screened these alkaloids for their ability to inhibit enzymes involved in cognitive function and found that (-)-2-ethyl-3[2-(3-ethylpiperidinyl)-ethyl]-1H-indole has significant butyrylcholinesterase inhibition activity, with potential to cross the blood-brain barrier. This finding could help develop new treatments for neurodegenerative diseases.

NeurosciencePhytochemistry
Vrabec R et al (2022).
Phytochemistry.
DOI:
10.1016/j.phytochem.2021.113017
PubMed:
34798410

The Morphological and Anatomical Traits of the Leaf in Representative Vinca Species Observed on Indoor- and Outdoor-Grown Plants.

Ciorîță A et al (2021).
Plants (Basel).
DOI:
10.3390/plants10040622
PubMed:
33805226

First report of leaf blight caused by Phytophthora ramorum on periwinkle (Vinca minor) in Washington State, USA.

Elliott M et al (2021).
Plant Dis.
DOI:
10.1094/PDIS-08-20-1721-PDN
PubMed:
33560879

Phytochemical Investigation of Vinca minor Cultivated in Iran.

Phytochemistry
Farahanikia B et al (2011).
Iran J Pharm Res.
PubMed:
24250413

Indole alkaloids from Vinca major and V. minor growing in Turkey.

Phytochemistry
Bahadori F et al (2012).
Nat Prod Commun.
PubMed:
22816294