Viola tricolor

Common Names: Johnny-jump-up, pansy violet

Ethnobotanical Studies

Studies

Simultaneous Determination of 23 Pyrrolizidine and Tropane Alkaloids in Infusions from Dry Edible Flowers Using Optimized μSPEed(®) Microextraction Prior to Their Analysis by UHPLC-IT-MS/MS.

Phytochemistry
Fernández-Pintor B, Morante-Zarcero S and Sierra I (2024).
Foods.
DOI:
10.3390/foods13111740
PubMed:
38890967

Current use of medicinal plants for children's diseases among mothers in Southern Romania.

Petran M et al (2024).
Front Pharmacol.
DOI:
10.3389/fphar.2024.1377341
PubMed:
38841372

In vitro antimicrobial and antibiofilm screening of eighteen Iranian medicinal plants.

Summary

Iranian medicinal plants show promising antimicrobial properties, a potential low-cost solution to drug-resistant pathogens with minimal side effects. Crucial for developing new antibiotics.

Antimicrobial
Hamidi M et al (2024).
BMC Complement Med Ther.
DOI:
10.1186/s12906-024-04437-x
PubMed:
38549139

Exploring Immune Modulatory Effects of Cyclotide-Enriched Viola tricolor Preparations.

Retzl B et al (2023).
Planta Med.
DOI:
10.1055/a-2173-8627
PubMed:
37748505

A highly selective C-rhamnosyltransferase from Viola tricolor and insights into its mechanisms.

Han BY et al (2023).
Acta Pharm Sin B.
DOI:
10.1016/j.apsb.2023.05.011
PubMed:
37655315

Edible Herbal Medicines as an Alternative to Common Medication for Sleep Disorders: A Review Article.

Hosseini A et al (2023).
Curr Neuropharmacol.
DOI:
10.2174/1570159X21666230621143944
PubMed:
37345244

Case study of clinical improvement of atopic dermatitis in a patient treated with herbal-based parapharmaceuticals.

Dermatology
Maraschio A, Wulhfard K and Monsellato L (2023).
J Complement Integr Med.
DOI:
10.1515/jcim-2023-0005
PubMed:
37043584

Resonance Raman and Visible Micro-Spectroscopy for the In-Vivo and In-Vitro Characterization of Anthocyanin-Based Pigments in Blue and Violet Flowers: A Comparison with HPLC-ESI- MS Analysis of the Extracts.

Bruni S et al (2023).
Molecules.
DOI:
10.3390/molecules28041709
PubMed:
36838697

Growth and Physiological Response of Viola tricolor L. to NaCl and NaHCO(3) Stress.

Liu X and Su S (2023).
Plants (Basel).
DOI:
10.3390/plants12010178
PubMed:
36616311

Influence of Tagetes patula and Viola tricolor on survival of Staphylococcus aureus ATCC 25923.

Steinka I et al (2022).
Heliyon.
DOI:
10.1016/j.heliyon.2022.e11777
PubMed:
36439735

In vitro Inhibition of HIV-1 by Cyclotide-Enriched Extracts of Viola tricolor.

Conzelmann C et al (2022).
Front Pharmacol.
DOI:
10.3389/fphar.2022.888961
PubMed:
35712712

Effect of weather conditions, substrate pH, biochar amendment and plant species on two plant growth-promoting microbes on vegetated roofs and facades.

Xie L et al (2022).
Heliyon.
DOI:
10.1016/j.heliyon.2022.e09560
PubMed:
35677418

Discovery of the cyclotide caripe 11 as a ligand of the cholecystokinin-2 receptor.

Taghizadeh MS et al (2022).
Sci Rep.
DOI:
10.1038/s41598-022-13142-z
PubMed:
35654807

Prophylactic use of an ultra-diluted complex on health, metabolism, and performance of weaned Holstein calves and its carryover effect up to first lactation.

da Silva TH et al (2021).
J Dairy Sci.
DOI:
10.3168/jds.2021-20170
PubMed:
34538483

Differences in the functioning of photosynthetic electron transport between metallicolous and non-metallicolous populations of the pseudometallophyte Viola tricolor.

Pilarska M et al (2020).
J Plant Physiol.
DOI:
10.1016/j.jplph.2020.153185
PubMed:
32497866

Ex vivo and in vivo studies of Viola tricolor Linn. as potential cardio protective and hypotensive agent: Inhibition of voltage-gated Ca(++) ion channels.

Summary

Viola tricolor Linn. is a traditional medicine used for its cardio-protective and anti-hypertensive effects. The study aimed to evaluate its effects in in vitro and in vivo studies. The crude extract and its fractions were tested on rabbit atria and aorta, and the blood pressure was measured in normotensive ketamine-diazepam anesthetized rats. The results show that Viola tricolor L. has cardio-relaxant, vasorelaxant, hypotensive, and cardioprotective effects mediated through Voltage dependent L-type calcium channels blockage. The study suggests that Viola tricolor L. can be used to treat cardiovascular disorders.

CardiologyNeuroscience
Saqib F et al (2020).
FASEB J.
DOI:
10.1096/fj.202000658R
PubMed:
32475023

Clinical Effectiveness of a Combination of Black Elder Berries, Violet Herb, and Calendula Flowers in Chronic Obstructive Pulmonary Disease: The Results of a Double-Blinded Placebo-Controlled Study.

Kirichenko TV et al (2020).
Biology (Basel).
DOI:
10.3390/biology9040083
PubMed:
32331341

Reporting a Transcript from Iranian Viola Tricolor, Which May Encode a Novel Cyclotide-Like Precursor: Molecular and in silico Studies.

Khoshkam Z et al (2020).
Comput Biol Chem.
DOI:
10.1016/j.compbiolchem.2019.107168
PubMed:
31791808

Anticonvulsant Activity of Viola tricolor against Seizures Induced by Pentylenetetrazol and Maximal Electroshock in Mice.

Summary

Scientists conducted a study to investigate the anticonvulsant effects of a medicinal plant on seizure models induced by two different methods. The medicinal plant showed potential as a therapy for human neurodegenerative diseases such as epilepsy. However, further research is needed to fully explore its effectiveness.

Neuroscience
Baradaran Rahimi V et al (2019).
Iran J Med Sci.
PubMed:
31182888

Effects of Viola tricolor Flower Hydroethanolic Extract on Lung Inflammation in a Mouse Model of Chronic Asthma.

Immunology
Harati E et al (2018).
Iran J Allergy Asthma Immunol.
PubMed:
30518183

Protective effect of Viola tricolor and Viola odorata extracts on serum/glucose deprivation-induced neurotoxicity: role of reactive oxygen species.

Summary

The study investigated the potential of Viola tricolor and Viola odorata to protect brain cells from damage caused by oxygen deprivation and neurodegenerative disorders. The research was conducted in vitro using an SGD-induced cell death model. The results showed that both plant species have antioxidant properties that protect neurons from damage. The findings suggest that these plants may have therapeutic potential in preventing or treating brain ischemia and neurodegenerative diseases.

Neuroscience
Mousavi SH et al (2016).
Avicenna J Phytomed.
PubMed:
27516984

Viola tricolor induces apoptosis in cancer cells and exhibits antiangiogenic activity on chicken chorioallantoic membrane.

Cancer
Sadeghnia HR et al (2014).
Biomed Res Int.
DOI:
10.1155/2014/625792
PubMed:
25243166

Immunosuppressive activity of an aqueous Viola tricolor herbal extract.

Hellinger R et al (2014).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2013.10.044
PubMed:
24216163