Common Names: fox grape
Scientists analyzed the genomes of cultivated and wild grapevines to understand their genetic diversity. They found differences in gene zygosity, segmental duplications, and transposable element polymorphisms, which contribute to grapevine genome diversification. This information can aid breeding programs for improved grapevine traits.
Isabella grapes contain phenolic compounds that have beneficial effects on human health, including potential anti-breast cancer properties. A study conducted in Colombia used ultrasound-assisted extraction to obtain a crude extract with antioxidant properties and high polyphenol content. The extract induced a decrease in the viability of breast cancer cells by affecting mitochondrial function and increasing reactive oxygen species. Molecular docking simulations also suggested that the phenolic compounds could interact with proteins involved in apoptosis. These findings highlight the potential of Isabella grape phenolic compounds as adjuvant chemopreventive agents for breast cancer treatment.