Wikstroemia indica

Ethnobotanical Studies

Studies

Daphnoretin inhibited SCI-induced inflammation and activation of NF-κB pathway in spinal dorsal horn.

Summary

Daphnoretin, a compound from nature, shows potential in reducing inflammation and activating a key pathway after spinal cord injury. This research may lead to safer and more effective treatments for SCI.

Immunology
Wu J, Lin F and Chen B (2024).
Aging (Albany NY).
DOI:
10.18632/aging.205893
PubMed:
38843384

Study of the mechanism underlying the anti-inflammatory effect of Miao medicine comprising raw and processed Radix Wikstroemia indica using the "sweat soaking method".

Summary

Scientists studied the anti-inflammatory effects of raw and processed Radix Wikstroemia indica using the "sweat soaking method" in Miao medicine. Results may influence the use and understanding of this traditional medicine.

Immunology
Song X et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.117770
PubMed:
38219877

Wikstroemia indica (L.) C. A. Mey. Exerts analgesic activity by inhibiting NaV1.7 channel.

Summary

Researchers explored the pain-relieving effects of Wikstroemia indica, a medicinal plant with numerous benefits but no previous studies on analgesic properties. This finding holds significance for those seeking natural alternatives for pain relief.

Pain
Zhang K et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117392
PubMed:
37949328

Identification of Daphnane Diterpenoids from Wikstroemia indica Using Liquid Chromatography with Tandem Mass Spectrometry.

Phytochemistry
Zhang M et al (2023).
Plants (Basel).
DOI:
10.3390/plants12203620
PubMed:
37896083

H-NMR-based metabolomics study on the effects of raw and processed radix Wikstroemia indica on endogenous metabolites in rat plasma.

Summary

Researchers investigated the effects of the "Sweat soaking method" on Radix Wikstroemia indica (RWI) by analyzing blood samples. Processed RWI showed potential detoxification properties by regulating various metabolic pathways, reducing hepatotoxicity and nephrotoxicity.

Phytochemistry
Xue-Li Song - et al (2023).
Pak J Pharm Sci.
PubMed:
37580929

Naturally Occurring Bicoumarin Compound Daphnoretin Inhibits Growth and Induces Megakaryocytic Differentiation in Human Chronic Myeloid Leukemia Cells.

Cancer
Huang YC et al (2022).
Cells.
DOI:
10.3390/cells11203252
PubMed:
36291120

A nano-preparation approach to enable the delivery of daphnoretin to potentiate the therapeutical efficacy in hepatocellular cancer.

Cancer
Zhu G et al (2022).
Front Pharmacol.
DOI:
10.3389/fphar.2022.965131
PubMed:
36249790

(1)H-NMR-based metabolic profiling of rat urine to assess the toxicity-attenuating effect of the sweat-soaking method on Radix Wikstroemia indica.

Phytochemistry
Zhou ZR et al (2022).
Exp Ther Med.
DOI:
10.3892/etm.2022.11392
PubMed:
35747156

Three new compounds from the dried root bark of Wikstroemia indica and their cytotoxicity against HeLa cells.

Shi P et al (2022).
Nat Prod Res.
DOI:
10.1080/14786419.2021.2016749
PubMed:
34965788

Diarylpentanones from the root of Wikstroemia indica and their cytotoxic activity against human lung A549 cells.

Liu Z et al (2021).
Nat Prod Res.
DOI:
10.1080/14786419.2019.1698577
PubMed:
34590506

Comprehensive investigation of pharmacodyamic material basis of Wikstroemia indica (L.) C. A. Mey. by serum pharmacochemistry and bivariate correlation analysis.

Wang J et al (2021).
J Chromatogr B Analyt Technol Biomed Life Sci.
DOI:
10.1016/j.jchromb.2021.122770
PubMed:
34325311

Curcumin and wikstroflavone B, a new biflavonoid isolated from Wikstroemia indica, synergistically suppress the proliferation and metastasis of nasopharyngeal carcinoma cells via blocking FAK/STAT3 signaling pathway.

Immunology
Shao M et al (2020).
Phytomedicine.
DOI:
10.1016/j.phymed.2020.153341
PubMed:
32992086

Wikstromol from Wikstroemia indica induces apoptosis and suppresses migration of MDA-MB-231 cells via inhibiting PI3K/Akt pathway.

Yao H et al (2021).
J Nat Med.
DOI:
10.1007/s11418-020-01447-0
PubMed:
32865667

Quercitrin, the Main Compound in Wikstroemia indica, Mitigates Skin Lesions in a Mouse Model of 2,4-Dinitrochlorobenzene-Induced Contact Hypersensitivity.

Jegal J et al (2020).
Evid Based Complement Alternat Med.
DOI:
10.1155/2020/4307161
PubMed:
32695208

Suppression of DNCB-Induced Atopic Skin Lesions in Mice by Wikstroemia indica Extract.

Lee SY et al (2020).
Nutrients.
DOI:
10.3390/nu12010173
PubMed:
31936273

Bioactive components and pharmacological action of Wikstroemia indica (L.) C. A. Mey and its clinical application.

Review
Li YM et al (2009).
Curr Pharm Biotechnol.
PubMed:
19939213