Zanthoxylum bungeanum

Ethnobotanical Studies

Studies

First Report of Curvularia trifolii Causing Leaf Spot on Zanthoxylum bungeanum in China.

Cheng K et al (2024).
Plant Dis.
DOI:
10.1094/PDIS-06-24-1339-PDN
PubMed:
39215502

Preparation of Complex Polysaccharide Gels with Zanthoxylum bungeanum Essential Oil and Their Application in Fish Preservation.

Phytochemistry
Xue S, Li C and Xiong Z (2024).
Gels.
DOI:
10.3390/gels10080533
PubMed:
39195062

Chemotaxonomic variation of volatile components in Zanthoxylum Bungeanum peel and effects of climate on volatile components.

Wu Y et al (2024).
BMC Plant Biol.
DOI:
10.1186/s12870-024-05485-8
PubMed:
39169301

Correlation between climatic environment and characteristic components of 14 kinds of huajiao by thermal analysis techniques, GC-MS and HS-IMS.

Chang D et al (2024).
Food Sci Nutr.
DOI:
10.1002/fsn3.4126
PubMed:
39055205

Development of Zanthoxylum bungeanum essential oil Pickering emulsions using potato protein-chitosan nanoparticles and its application in mandarin preservation.

Phytochemistry
Shen G et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.134100
PubMed:
39048005

ZbMYB111 Expression Positively Regulates ZbUFGT-Mediated Anthocyanin Biosynthesis in Zanthoxylum bungeanum with the Involvement of ZbbHLH2.

Zhang J et al (2024).
J Agric Food Chem.
DOI:
10.1021/acs.jafc.3c08579
PubMed:
39024128

Ultrasonic-assisted extraction of total flavonoids from Zanthoxylum bungeanum residue and their allelopathic mechanism on Microcystis aeruginosa.

Phytochemistry
Cheng J et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-64129-x
PubMed:
38851826

Degradation and transformation mechanisms of pungent substances in huajiao (Zanthoxylum bungeanum) oil during storage: Induced by ultraviolet irradiation.

Duan P et al (2024).
Food Chem.
DOI:
10.1016/j.foodchem.2024.139674
PubMed:
38824728

Dietary Replacement of Soybean Meal with Zanthoxylum bungeanum Seed Meal on Growth Performance, Blood Parameters, and Nutrient Utilization in Broiler Chickens.

Chen X et al (2024).
Animals (Basel).
DOI:
10.3390/ani14101420
PubMed:
38791638

Nanoporous Carbon Materials Derived from Zanthoxylum Bungeanum Peel and Seed for Electrochemical Supercapacitors.

Jia P et al (2024).
Nanomaterials (Basel).
DOI:
10.3390/nano14100836
PubMed:
38786793

A novel isoquinoline alkaloid HJ-69 isolated from Zanthoxylum bungeanum attenuates inflammatory pain by inhibiting voltage-gated sodium and potassium channels.

Summary

Scientists studied isoquinoline alkaloids in Z. bungeanum for potential medicinal benefits. This plant has traditional use for arthritis and toothache in Asia. Research may lead to new treatments.

ImmunologyNeurosciencePainPhytochemistry
Wang L et al (2024).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2024.118218
PubMed:
38677570

Zanthoxylum bungeanum Waste-Derived High-Nitrogen Self-Doped Porous Carbons as Efficient Adsorbents for Methylene Blue.

Zhao Y et al (2024).
Molecules.
DOI:
10.3390/molecules29081809
PubMed:
38675629

Genomic survey and expression analysis of cellulose synthase superfamily and COBRA-like gene family in Zanthoxylum bungeanum stipule thorns.

Genetics
Gao W et al (2024).
Physiol Mol Biol Plants.
DOI:
10.1007/s12298-024-01432-x
PubMed:
38633272

Identification, Characterization, Cloning, and Cross-Reactivity of Zan b 2, a Novel Pepper Allergen of 11S Legumin.

Hu J et al (2024).
J Agric Food Chem.
DOI:
10.1021/acs.jafc.4c00351
PubMed:
38551197

Optimization of Conditions of Zanthoxylum Alkylamides Liposomes by Response Surface Methodology and the Absorption Characteristics of Liposomes in the Caco-2 Cell Monolayer Model.

Wang R et al (2024).
ACS Omega.
DOI:
10.1021/acsomega.4c00074
PubMed:
38463333

In Vitro Metabolism and In Vivo Pharmacokinetics Profiles of Hydroxy-α-Sanshool.

Meng J et al (2024).
Toxics.
DOI:
10.3390/toxics12020100
PubMed:
38393195

Safety and efficacy of a class II medical device based on highly purified and standardized plant extracts in the management of post-menopausal patients with vulvar and vaginal atrophy: a single-center prospective observational study.

Galli V et al (2024).
Minerva Obstet Gynecol.
DOI:
10.23736/S2724-606X.23.05409-X
PubMed:
38358384

Rapid classification and identification of chemical components in three different Zanthoxylum species by ultra-high-performance-liquid chromatography quadrupole-orbitrap-mass spectrometry.

Summary

This study used advanced technology to identify and classify the chemical components of different varieties of Zanthoxylum, a medicinal herb. It identified 48 common and 24 different components, providing valuable insights for studying its medicinal properties and ensuring quality control.

Phytochemistry
Shu L et al (2024).
J Sep Sci.
DOI:
10.1002/jssc.202300670
PubMed:
38356230

Research advances of Zanthoxylum bungeanum Maxim. polyphenols in inflammatory diseases.

Summary

This review explores the use of Chinese prickly ash in treating inflammatory conditions. Its polyphenolic components have shown promise in animal models for diseases like ulcerative colitis and arthritis. More research is needed to understand their mechanisms and develop safe therapeutic applications.

Review Immunology
Qi J et al (2024).
Front Immunol.
DOI:
10.3389/fimmu.2024.1305886
PubMed:
38343532

Rapid purification of alkylamides from Zanthoxylum bungeanum by medium-pressure liquid chromatography and the establishment of a numbness prediction model using an electronic tongue.

Phytochemistry
Wang P et al (2024).
Anal Methods.
DOI:
10.1039/d3ay02015k
PubMed:
38312040

Chitosan/oxidized Konjac Glucomannan films incorporated with Zanthoxylum Bungeanum essential oil: A novel approach for extending the shelf life of meat.

Phytochemistry
Chen Z et al (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.129683
PubMed:
38296664

Effects of Sichuan pepper (huājiāo) powder on disease activity and caecal microbiota of dextran sodium sulphate-induced inflammatory bowel disease mouse model.

Summary

Sichuan pepper (huājiāo) has strong antioxidant and bile acid-lowering properties. It also modulates inflammation-related cytokines and gut microbiota in mice on a low-fiber, high-sucrose diet.

GastroenterologyImmunology
Miyashita A et al (2024).
Mol Biol Rep.
DOI:
10.1007/s11033-023-09103-y
PubMed:
38236446

Effects of High-Pressure Homogenization Treatment on the Development of Antioxidant Zanthoxylum bungeanum Leaf Powder Films for Preservation of Fresh-Cut Apple.

Immunology
Li F et al (2023).
Foods.
DOI:
10.3390/foods13010022
PubMed:
38201049

A new pepper allergen Zan b 1.01 of 2S albumins: Identification, cloning, characterization, and cross-reactivity.

Li H et al (2024).
Asian Pac J Allergy Immunol.
DOI:
10.12932/AP-300423-1595
PubMed:
38183644

Degradation and Transformation Mechanisms of Zanthoxylum Alkylamides Exposed to UVB Light.

Wang R et al (2023).
Foods.
DOI:
10.3390/foods12244392
PubMed:
38137195

Combining with volatilomic profiling and chemometrics to explore the volatile characteristics in five different dried Zanthoxylum bungeanum maxim.

Feng J et al (2024).
Food Res Int.
DOI:
10.1016/j.foodres.2023.113719
PubMed:
38128985

High-Efficiency Corrosion Inhibitor of Biomass-Derived High-Yield Carbon Quantum Dots for Q235 Carbon Steel in 1 M HCl Solution.

Dong L et al (2023).
ACS Omega.
DOI:
10.1021/acsomega.3c06702
PubMed:
38107954

First Report of Leaf Spot on Zanthoxylum bungeanum Caused by Nigrospora sphaerica in China.

Zeng Y et al (2023).
Plant Dis.
DOI:
10.1094/PDIS-10-23-2214-PDN
PubMed:
38105455

Rapid determination of geographical authenticity and pungency intensity of the red Sichuan pepper (Zanthoxylum bungeanum) using differential pulse voltammetry and machine learning algorithms.

Zhang D et al (2023).
Food Chem.
DOI:
10.1016/j.foodchem.2023.137978
PubMed:
38048663

WGX50 mitigates doxorubicin-induced cardiotoxicity through inhibition of mitochondrial ROS and ferroptosis.

Tai P et al (2023).
J Transl Med.
DOI:
10.1186/s12967-023-04715-1
PubMed:
37978379

A Simple and Rapid High-Performance Liquid Chromatography Method for Preparation and Content Detection of the Mainly Numbing Taste Substances of Zanthoxylum bungeanum Maxim.

Summary

Researchers developed a method to obtain high-purity monomers of hydroxyl-α-sanshool and hydroxyl-β-sanshool, which are important indicators of Zanthoxylum bungeanum quality. Significant variation in these compounds was found among different types of Z. bungeanum.

Phytochemistry
Wang Z et al (2023).
J Chromatogr Sci.
DOI:
10.1093/chromsci/bmad087
PubMed:
37974461

Plant Extracts as Skin Care and Therapeutic Agents.

Review
Michalak M et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms242015444
PubMed:
37895122

Transcriptomics integrated with metabolomics to characterize key pigment compounds and genes related to anthocyanin biosynthesis in Zanthoxylum bungeanum peel.

Summary

Flavonoids are key pigments in Zanthoxylum bungeanum, with cyanidin-3-O-rutinoside and cyanidin-3-O-glucoside critical for peel color. Three anthocyanin synthesis genes were identified, aiding in quality control and utilization of the plant.

Genetics
Han N et al (2023).
Physiol Plant.
DOI:
10.1111/ppl.14031
PubMed:
37882301

Soy protein isolate-based active films functionalized with Zanthoxylum bungeanum by-products: Effects on barrier, mechanical, antioxidant and cherry tomato preservation performance.

Summary

This study found that adding ZBLE to soy protein films improved their strength, water barrier properties, UV-light resistance, and antioxidant activities. Films with 5% ZBLE performed the best. The addition of ZBLE also extended the storage time of cherry tomatoes, making it a potential eco-friendly packaging material for food preservation.

Immunology
Yu M et al (2023).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2023.127539
PubMed:
37858653

Hydroxy-α-sanshool from the fruits of Zanthoxylum bungeanum Maxim. promotes browning of white fat by activating TRPV1 to induce PPAR-γ deacetylation.

Zhang Q et al (2023).
Phytomedicine.
DOI:
10.1016/j.phymed.2023.155113
PubMed:
37748388

Activated carbon with high mesopore ratio derived from waste Zanthoxylum bungeanum branches by KNO(3)-assisted H(3)PO(4) staged activation for toluene adsorption.

Xie H et al (2023).
Environ Sci Pollut Res Int.
DOI:
10.1007/s11356-023-29806-w
PubMed:
37697201

The balanced unsaturated fatty acid supplement constituted by woody edible oils improved lipid metabolism and gut microbiota in high-fat diet mice.

Gastroenterology
Chen X et al (2023).
Front Nutr.
DOI:
10.3389/fnut.2023.1203932
PubMed:
37545586

The Role of Gut Microbiota in Anxiety, Depression, and Other Mental Disorders as Well as the Protective Effects of Dietary Components.

Summary

Imbalance of gut bacteria affects mental health; dietary components like probiotics and spices can help prevent mental disorders.

Review GastroenterologyNeuroscience
Xiong RG et al (2023).
Nutrients.
DOI:
10.3390/nu15143258
PubMed:
37513676

Forest Ecosystem Service Trade-Offs/Synergies and System Function Optimization in Karst Desertification Control.

Xiong K et al (2023).
Plants (Basel).
DOI:
10.3390/plants12122376
PubMed:
37376000

Multi-environment evaluations across ecological regions reveal climate and soil effects on amides contents in Chinese prickly ash peels (Zanthoxylum bungeanum Maxim.).

Zheng T et al (2023).
BMC Plant Biol.
DOI:
10.1186/s12870-023-04328-2
PubMed:
37308832

Efficient preparation of hyperoside and quercitrin from Zanthoxylum bungeanum Maxim leaves using an integrated surfactant-based aqueous two-phase system, back-extraction and adsorption separation.

Han N et al (2023).
Nat Prod Res.
DOI:
10.1080/14786419.2023.2219822
PubMed:
37287217

An overview of natural products that modulate the expression of non-coding RNAs involved in oxidative stress and inflammation-associated disorders.

Summary

This review discusses the role of oxidative stress and inflammation in various diseases and highlights natural products that target non-coding RNAs to combat these disorders. Several natural products, including Baicalein, Curcumin, and Resveratrol, are effective in controlling oxidative stress and inflammation. Other compounds, such as Peppermint and Gingerol, show potential in treating these disorders but their effect on non-coding RNAs is unknown. Further research in this area will be valuable in developing natural compounds for therapy.

Review Immunology
Ngum JA et al (2023).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1144836
PubMed:
37168992

Development of a general separation strategy by countercurrent chromatography using sanshools from Zanthoxylum bungeanum oleoresin as a case study.

Phytochemistry
Han T et al (2023).
J Sep Sci.
DOI:
10.1002/jssc.202300115
PubMed:
37158371

Zanthoxylum bungeanum seed oil inhibits tumorigenesis of human melanoma A375 by regulating CDC25A/CyclinB1/CDK1 signaling pathways in vitro and in vivo.

Wang W et al (2023).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1165584
PubMed:
37081962

Preliminary Study on Insecticidal Potential and Chemical Composition of Five Rutaceae Essential Oils against Thrips flavus (Thysanoptera: Thripidae).

Pei TH et al (2023).
Molecules.
DOI:
10.3390/molecules28072998
PubMed:
37049761

Anti-Inflammatory and Anti-Osteoclastogenesis Activities of Different Kinds of Zanthoxylum bungeanum Seed Oil in vitro.

Immunology
Zhang B et al (2023).
Chem Biodivers.
DOI:
10.1002/cbdv.202201157
PubMed:
37029634

Compounds isolated from the pericarp of Zanthoxylum bungeanum and inhibitory activity against LPS-induced NO production in RAW264.7.

Liu JY et al (2023).
J Asian Nat Prod Res.
DOI:
10.1080/10286020.2023.2188203
PubMed:
36916389

Investigation on the Mechanisms of Zanthoxylum bungeanum for Treating Diabetes Mellitus Based on Network Pharmacology, Molecular Docking, and Experiment Verification.

Diabetes
Huang Y et al (2023).
Biomed Res Int.
DOI:
10.1155/2023/9298728
PubMed:
36874926

Antibacterial activity and synergic effects of the essential oils of Amomum verum Blackw and Zanthoxylum limonella (Dennst.) Alston.

Phytochemistry
Khruengsai S, Sripahco T and Pripdeevech P (2023).
Arch Microbiol.
DOI:
10.1007/s00203-023-03436-9
PubMed:
36862257

Characterization of Polysaccharides from the Pericarp of Zanthoxylum bungeanum Maxim by Saccharide Mapping and Their Neuroprotective Effects.

Summary

This study investigated the properties of the pericarp of maxim (PZM), a common Chinese spice and herbal medicine. Using various techniques, the study found that PZM contained certain chemical compounds that helped protect PC12 cells from oxidative damage induced by Aβ, a peptide linked to Alzheimer's disease. PZM treatment increased cell viability, reduced ROS levels, and downregulated caspase-3 and Bax mRNA expressions while upregulating Bcl-2 and Nrf2/HO-1 expressions. These findings suggest that PZM could be used as a potential protective agent against Aβ-induced neurotoxicity.

Neuroscience
Hu MB et al (2023).
Molecules.
DOI:
10.3390/molecules28041813
PubMed:
36838801

Chemical composition, chemotypic characterization, and histochemical localization of volatile components in different cultivars of Zanthoxylum bungeanum Maxim. leaves.

Xu S et al (2023).
J Food Sci.
DOI:
10.1111/1750-3841.16490
PubMed:
36786362

Zanthoxylum bungeanum as a natural pickling spice alleviates health risks in animal-derived foods via up-regulating glutathione S-transferase, down-regulating cytochrome P450 1A.

Jia W and Wang X (2023).
Food Chem.
DOI:
10.1016/j.foodchem.2023.135535
PubMed:
36701916

Integrative multi-omics unravels the amelioration effects of Zanthoxylum bungeanum Maxim. on non-alcoholic fatty liver disease.

Huang X et al (2023).
Phytomedicine.
DOI:
10.1016/j.phymed.2022.154576
PubMed:
36610127

Evaluation of climate factors affecting the quality of red huajiao (Zanthoxylum bungeanum maxim.) based on UPLC-MS/MS and MaxEnt model.

Zheng T et al (2022).
Food Chem X.
DOI:
10.1016/j.fochx.2022.100522
PubMed:
36519100

The current situation of Zanthoxylum bungeanum industry and the research and application prospect. A review.

Review
Bao Y et al (2023).
Fitoterapia.
DOI:
10.1016/j.fitote.2022.105380
PubMed:
36462661

Comparative metabolomics analysis of pericarp from four varieties of Zanthoxylum bungeanum Maxim.

Cao Y et al (2022).
Bioengineered.
DOI:
10.1080/21655979.2022.2108632
PubMed:
36274249

Chemical constituents from the roots of Zanthoxylum bungeanum Maxim. and their neuroprotective activities.

Summary

Scientists isolated and identified 22 compounds from the roots of Zanthoxylum bungeanum Maxim., including two previously unknown ones. They used various techniques to determine the chemical structures of the compounds and found that they had antioxidant properties. One of the compounds, number 18, protected nerve cells from damage.

Neuroscience
Ma LM et al (2022).
Fitoterapia.
DOI:
10.1016/j.fitote.2022.105337
PubMed:
36265759

The complex genome and adaptive evolution of polyploid Chinese pepper (Zanthoxylum armatum and Zanthoxylum bungeanum).

Genetics
Hu L et al (2023).
Plant Biotechnol J.
DOI:
10.1111/pbi.13926
PubMed:
36117410

Insights into the catalytic and regulatory mechanisms of dihydroflavonol 4-reductase, a key enzyme of anthocyanin synthesis in Zanthoxylum bungeanum.

Aiguo Z et al (2023).
Tree Physiol.
DOI:
10.1093/treephys/tpac101
PubMed:
36054375

Zanthoxylum bungeanum root-rot associated shifts in microbiomes of root endosphere, rhizosphere, and soil.

Liao LB et al (2022).
PeerJ.
DOI:
10.7717/peerj.13808
PubMed:
35945942

Study on the antipruritic mechanism of Zanthoxylum bungeanum and Zanthoxylum schinifolium volatile oil on chronic eczema based on H1R and PAR-2 mediated GRPR pathway.

Dermatology
Zhou XL, Chen LL and Wang JF (2022).
Allergol Immunopathol (Madr).
DOI:
10.15586/aei.v50i4.486
PubMed:
35789407

Conversion effects of farmland to Zanthoxylum bungeanum plantations on soil organic carbon mineralization in the arid valley of the upper reaches of Yangtze River, China.

Lv C et al (2022).
PLoS One.
DOI:
10.1371/journal.pone.0262961
PubMed:
35120155

Genome survey of Zanthoxylum bungeanum and development of genomic-SSR markers in congeneric species.

Genetics
Li J et al (2020).
Biosci Rep.
DOI:
10.1042/BSR20201101
PubMed:
32558907

Zanthoxylum bungeanum Maxim. (Rutaceae): A Systematic Review of Its Traditional Uses, Botany, Phytochemistry, Pharmacology, Pharmacokinetics, and Toxicology.

Review Phytochemistry
Zhang M et al (2017).
Int J Mol Sci.
DOI:
10.3390/ijms18102172
PubMed:
29057808