Zingiber officinale

Common Names: garden ginger

Ethnobotanical Studies

Clinical Trials

The effect of zingiber officinale on prooxidant-antioxidant balance and glycemic control in diabetic patients with ESRD undergoing hemodialysis: a double-blind randomized control trial.

This study investigated the impact of ginger supplementation on oxidative balance, blood sugar control, and kidney function in diabetic patients undergoing hemodialysis.

Rostamkhani H et al (2023).
BMC Complement Med Ther.
PubMed:
36800950

Studies

Zingiber officinale Ameliorates Acute Toxoplasmosis-Induced Pathology in Mice.

El-Kady AM et al (2024).
Acta Parasitol.
PubMed:
39225734

Effectivity of oral ginger supplementation for chemotherapy induced nausea and vomiting (CINV) in children: A systematic review of clinical trials.

Summary

Ginger supplementation reduces chemotherapy-induced nausea and vomiting in children, with a low risk of bias and no reported adverse effects. Standardized studies are needed to confirm these findings.

Review Cancer
Hardi H, Estuworo GK and Louisa M (2024).
J Ayurveda Integr Med.
PubMed:
39173346

Assessment of the anticancer potential of certain phenolic and flavonoid components in ginger capsules using colorectal cancer cell lines coupled with quantitative analysis.

Summary

Researchers found that ginger extract had strong anticancer effects on colorectal cancer cells, with high levels of quercetin. This suggests potential for novel and more effective CRC treatments using ginger supplements.

Al Azzam KM et al (2024).
Biomed Chromatogr.
PubMed:
39152776

Cedrol in ginger (Zingiber officinale) as a promising hair growth drug: The effects of oral and external administration on hair regeneration and its mechanism.

Li T et al (2024).
Bioorg Chem.
PubMed:
39137599

Comprehensive investigation of niosomal red palm wax gel encapsulating ginger (Zingiber officinale Roscoe): Network pharmacology, molecular docking, In vitro studies and phase 1 clinical trials.

Ongtanasup T et al (2024).
Int J Biol Macromol.
PubMed:
39094890

A comprehensive analysis of aroma quality and perception mechanism in ginger-infused stewed beef using instrumental analysis, sensory evaluation and molecular docking.

Zhao Y et al (2024).
Food Chem.
PubMed:
39089043

Non-targeted metabolomics and explainable artificial intelligence: Effects of processing and color on coniferyl aldehyde levels in Eucommiae cortex.

Pan Y et al (2024).
Food Chem.
PubMed:
39089015

Therapeutic effects of OXY- Exo(Aloe) in diabetic wound injury.

Summary

OXY-Exo, made from aloe vera gel, ginger juice, and neem fruit sap, accelerates diabetic wound healing by increasing oxygenation, reducing inflammation, and promoting tissue remodeling. Safe and effective, it has no reported side effects.

Miya MB et al (2024).
Biochem Biophys Res Commun.
PubMed:
39032360

Exploring gingerol glucosides with enhanced anti-inflammatory activity through a newly identified α-glucosidase (ArG) from Agrobacterium radiobacter DSM 30147.

Chang TS et al (2024).
J Biosci Bioeng.
PubMed:
38997871

Insights into the microbial assembly and metabolites associated with ginger (Zingiber officinale L. Roscoe) microbial niches and agricultural environments.

Wang W et al (2024).
Sci Total Environ.
PubMed:
38992353

Revealing the material basis and mechanism for the inhibition of intestinal peristalsis by Zingiber officinale Roscoe through integrated metabolomics, serum pharmacochemistry, and network pharmacology.

Xiong L et al (2024).
Biomed Chromatogr.
PubMed:
38922712

Identification of putative α-glucosidase inhibitors and antioxidants in Zingiber officinale rhizome using LCMS-based metabolomics and in silico molecular docking.

Maniam N et al (2024).
Nat Prod Res.
PubMed:
38919043

Comparative pharmacokinetics of multi-components in normal and stomach cold syndrome rats after oral administration of Zingiberis Rhizoma - Jujubae Fructus herb pair and its single herb extracts by UHPLC-MS/MS.

Xu X et al (2024).
J Chromatogr B Analyt Technol Biomed Life Sci.
PubMed:
38865851

Peppermint essential oil enhances the vase life of Dendrobium orchids.

Summary

Peppermint essential oil extends vase life of orchids, improves quality, and is eco-friendly. Use as a natural alternative to synthetic chemicals in holding solutions for cut flowers.

Teerarak M, Pilasombut K and Laosinwattana C (2024).
Heliyon.
PubMed:
38845939

Perilla juice and ginger juice reduced warmed-over flavor (WOF) in surimi gels: Due to the inhibition of the formation of the WOF compounds and the masking of the WOF.

Dang M et al (2024).
Food Chem.
PubMed:
38820632

UPLC-ESI-Q-TOF-MS/MS based metabolomics investigation on chemical constituent consistency of Zhenwu Decoction before and after compatibility.

Su Y et al (2024).
J Pharm Biomed Anal.
PubMed:
38763106

6-Gingerol ameliorates ulcerative colitis by inhibiting ferroptosis based on the integrative analysis of plasma metabolomics and network pharmacology.

Li W et al (2024).
Food Funct.
PubMed:
38753306

Growth performance, carcass traits and meat physical characteristics of growing Japanese quail fed ginger powder and frankincense oil as feed additives.

Mohamed LA et al (2024).
Poult Sci.
PubMed:
38749109

Evaluation of cytotoxic effect of siphonochilone from African ginger: an in vitro analysis.

Ortigosa-Palomo A et al (2024).
Environ Toxicol.
PubMed:
38742918

Intra-peritoneal lavage of Zingiber officinale rhizome and its active constituent gingerol impede inflammation, angiogenesis, and fibrosis following post-operative peritoneal adhesion in male rats.

Yahyazadeh R et al (2024).
Saudi Pharm J.
PubMed:
38737808

Potentially functional lactose-free ice cream with Lacticaseibacillus casei CSL3, ginger, and honey.

Massaut KB et al (2024).
Braz J Microbiol.
PubMed:
38727922

Rapid and simultaneous determination of curcuminoids and gingerols in food products containing turmeric and ginger using paper spray mass spectrometry.

Bartella L et al (2024).
J Mass Spectrom.
PubMed:
38726689

Da-Chai-Hu-Tang Formula inhibits the progression and metastasis in HepG2 cells through modulation of the PI3K/AKT/STAT3-induced cell cycle arrest and apoptosis.

Duan ZW et al (2024).
J Ethnopharmacol.
PubMed:
38705430

Microencapsulation of ginger essential oil using mung bean protein isolate-chitosan complex coacervates: Application in the preservation of crab meatballs and the prediction of shelf life.

Shen J, Zhang M and Yang C (2024).
Food Chem.
PubMed:
38657553

Mitigating digestive disorders: Action mechanisms of Mediterranean herbal active compounds.

Review
Kmail A et al (2024).
Open Life Sci.
PubMed:
38645751

Residue levels, processing factors and risk assessment of pesticides in ginger from market to table.

Cui K et al (2024).
J Hazard Mater.
PubMed:
38608592

Plant growth-promoting and biocontrol traits of endophytic Bacillus licheniformis against soft rot causing Pythium myriotylum in ginger plant.

Alarjani KM and Elshikh MS (2024).
J Basic Microbiol.
PubMed:
38578065

Correction to: Studies on photocatalytic mineralization of organic pesticides by bimetallic Cu-Zn nanoparticles derived from Zingiber officinale Roscoe (ginger) using green chemistry approach.

Singh G and Devi T (2024).
Environ Sci Pollut Res Int.
PubMed:
38558350

Development of Certified Reference Material Solutions for Phytochemicals in Ginger and Kava.

Aijaz SM et al (2024).
J AOAC Int.
PubMed:
38530970

Identification, rapid screening, docking mechanism and in vitro digestion stability of novel DPP-4 inhibitory peptides from wheat gluten with ginger protease.

Pu L et al (2024).
Food Funct.
PubMed:
38512162

6-Gingerol alleviates ectopic lipid deposition in skeletal muscle by regulating CD36 translocation and mitochondrial function.

Peng Z et al (2024).
Biochem Biophys Res Commun.
PubMed:
38493545

Suppression of P2X4 and P2X7 by Lactobacillus rhamnosus vitaP1: effects on hangover symptoms.

Kwon JE et al (2024).
AMB Express.
PubMed:
38491208

8-shogaol derived from dietary ginger alleviated acute and inflammatory pain by targeting TRPV1.

Summary

TL;DR: 8-Shogaol (8S) in ginger reduces inflammatory pain and morphine tolerance by activating TRPV1 channels. Potential new drug for pain relief.

Cheng XL et al (2024).
Phytomedicine.
PubMed:
38484627

Analytical quality by design based on knowledge organization: A case study of developing an ultrahigh-performance liquid chromatography method for the detection of phenolic compounds.

Tai Y et al (2024).
Phytochem Anal.
PubMed:
38462508

Preparation, characterization and drug release properties of pH sensitive Zingiber officinale polysaccharide hydrogel beads.

Jing Y et al (2024).
Int J Biol Macromol.
PubMed:
38395286

Herbal medicine for the prevention of chemotherapy-induced nausea and vomiting in patients with advanced colorectal cancer: A prospective randomized controlled trial.

Summary

Researchers investigated the use of Hezhong granules, a Chinese herbal medicine, for managing chemotherapy-induced nausea and vomiting (CINV). Although the key components of the granules show promising antiemetic and antitumor properties, there is a need for scientifically designed clinical trials to validate their efficacy and safety.

Wu Z et al (2024).
J Ethnopharmacol.
PubMed:
38341113

Ginger-derived bioactive compounds attenuate the Toll-like receptor mediated responses of human dendritic cells.

Pázmándi K et al (2024).
Eur J Pharmacol.
PubMed:
38331338

Evaluation of the efficacy and safety of a herbal formulation for rheumatoid arthritis - A non-inferiority randomized controlled trial.

Ahmad AUAM et al (2024).
J Ethnopharmacol.
PubMed:
38316221

Anti-microbial efficacy of a scientifically developed and standardized herbal-alcohol sanitizer.

Summary

Two herbal-alcohol-based hand sanitizers, containing Zingiber officinale and Ocimum sanctum, were found to be more effective than alcohol-based sanitizers in reducing microbial load, inhibiting influenza A virus, and causing less irritation to the skin. HS2 was particularly effective against viruses and the sanitizers have a longer shelf life.

Tulsawani R et al (2024).
Arch Microbiol.
PubMed:
38270599

Genome-wide analysis and expression pattern of the ZoPP2C gene family in Zingiber officinale Roscoe.

Summary

Researchers identified and studied the genome-scale of the PP2C gene family in ginger. Understanding these genes can provide insight into plant growth, development, signaling pathways, and responses to stresses.

Zhang P et al (2024).
BMC Genomics.
PubMed:
38245685

Zingiber officinale and thymus vulgaris extracts co-loaded polyvinyl alcohol and chitosan electrospun nanofibers for tackling infection and wound healing promotion.

Maleki H et al (2023).
Heliyon.
PubMed:
38223730

Pharmacodynamic components and mechanisms of ginger (Zingiber officinale) in the prevention and treatment of colorectal cancer.

Summary

Ginger has many beneficial properties like anti-inflammatory, antioxidant, and anticancer effects. It has a strong history in treating intestinal diseases and shows promise for preventing and treating colorectal cancer.

Xiang S et al (2024).
J Ethnopharmacol.
PubMed:
38218504

Characterization of active films based on chitosan/polyvinyl alcohol integrated with ginger essential oil-loaded bacterial cellulose and application in sea bass (Lateolabrax japonicas) packaging.

Chen X, Lan W and Xie J (2024).
Food Chem.
PubMed:
38211477

Bitter ginger (Zingiber zerumbet) for patients with solid tumors with no treatment options: A pilot clinical study.

de Queiroz LV et al (2024).
Complement Ther Med.
PubMed:
38199583

Comparative analyses reveal a phenylalanine ammonia lyase dependent and salicylic acid mediated host resistance in Zingiber zerumbet against the necrotrophic soft rot pathogen Pythium myriotylum.

Augustine L et al (2024).
Plant Sci.
PubMed:
38176527

Effect of microwave-assisted drying and extraction of 6-Shogaol from Zingiber officinale Roscoe.

Lohidasan S et al (2024).
Prep Biochem Biotechnol.
PubMed:
38174655

Anticancer activity of Curcuma aeroginosa essential oil and its nano-formulations: cytotoxicity, apoptosis and cell migration effects.

Summary

This study investigates the anticancer activity of Curcuma aeruginosa essential oil and its nano-formulations. Curcuma aeruginosa has potential in treating diseases and has various properties such as anti-HIV, hepatoprotective, antimicrobial, and anti-androgenic activities. Understanding its anticancer activity could have implications for cancer treatment.

Panyajai P et al (2024).
BMC Complement Med Ther.
PubMed:
38166788

Molecular docking, molecular dynamics simulation, and MM/PBSA analysis of ginger phytocompounds as a potential inhibitor of AcrB for treating multidrug-resistant Klebsiella pneumoniae infections.

Sahoo M et al (2024).
J Biomol Struct Dyn.
PubMed:
38165647

Mercury chloride causes cognitive impairment, oxidative stress and neuroinflammation in male Wistar rats: The potential protective effect of 6-gingerol-rich fraction of Zingiber officinale via regulation of antioxidant defence system and reversal of pro-inflammatory markers increase.

Asuku AO et al (2024).
Brain Res.
PubMed:
38157955

Induction of micro-rhizomes for in vitro ginger (Zingiber officinale Rosco) disease-free planting materials regeneration.

Gezahegn G, Feyisa T and Rezene Y (2023).
Biotechnol Rep (Amst).
PubMed:
38130937

Phytochemical profiling and anthelmintic potential of extracts of selected tropical plants on parasites of fishes in Epe Lagoon.

Summary

This research examined the anthelmintic properties of tropical plant extracts compared to praziquantel. Alligator pepper and neem extracts were most potent, and Aframomum melegueta and praziquantel were effective against all parasite classes with a wide safety margin for the fish host.

Ukwa UD, Saliu JK and Akinsanya B (2023).
Sci Rep.
PubMed:
38123590

Clinical dermatologic applications of ginger: a focused review.

Review
Alhanshali L and Khachemoune A (2024).
Int J Dermatol.
PubMed:
38102859

Therapeutic effects and mechanisms of action of ginger and its bioactive components on inflammatory response, oxidative stress, the immune system, and organ failure in sepsis: a comprehensive systematic review.

Velayati A et al (2023).
Nutr Rev.
PubMed:
38102801

2023 MASCC/ESMO consensus antiemetic guidelines related to integrative and non-pharmacological therapies.

Molassiotis A et al (2023).
Support Care Cancer.
PubMed:
38102373

Antimicrobial Efficacy of Allium cepa and Zingiber officinale Against the Milk-Borne Pathogen Listeria monocytogenes.

Summary

Researchers investigated the antibacterial effects of Allium cepa (onion) and Zingiber officinale (ginger) extracts against Listeria monocytogenes. A. cepa showed significant inhibitory activity, potentially targeting the virulence factor of the bacteria. Medicinal plants may serve as natural alternatives for treating listeriosis.

Arasu A et al (2023).
J Microbiol.
PubMed:
38048022

Home Remedies ("Paati Vaidyam") for Voice Disorders: Some Common Practices Among School Teachers.

Boominathan P et al (2023).
J Voice.
PubMed:
38030481

10‑Gingerol, a novel ginger compound, exhibits antiadipogenic effects without compromising cell viability in 3T3‑L1 cells.

Preciado-Ortiz ME et al (2023).
Biomed Rep.
PubMed:
38025831

Molecular identification of keratinophilic fungi associated with hair scalp and antifungal activity of green-synthesis zinc oxide nanoparticles.

Summary

Fungal imbalances in human hair and skin can lead to diseases. Scalp samples identified common yeast-like species, and ginger-derived zinc oxide nanoparticles have potential in controlling them. Proper care is crucial, and zinc oxide nanoparticles show promise in addressing the issue.

El-Dawy EGAEM et al (2023).
J Basic Microbiol.
PubMed:
38013254

The Mechanism of Core Chinese Medicine Combination in Treating Salivation.

Wang Y and Zhang Y (2023).
Stud Health Technol Inform.
PubMed:
38007798

Ethnobotanical study on medicinal plant knowledge among three ethnic groups in peri-urban areas of south-central Ethiopia.

Tamene S et al (2023).
J Ethnobiol Ethnomed.
PubMed:
37996915

Rapid quality evaluation and geographical origin recognition of ginger powder by portable NIRS in tandem with chemometrics.

Chen R et al (2024).
Food Chem.
PubMed:
37989021

Assessment of Heavy Metal Contents in Some Common Spices Available in the Local Market of North Shewa Zone, Oromia Regional State, Ethiopia.

Adugna T, Selale G and Regassa G (2023).
Biol Trace Elem Res.
PubMed:
37973776

Ginger (Zingiber Officinale Roscoe) ameliorates ethanol-induced cognitive impairment by modulating NMDA and GABA-A receptors in rat hippocampus.

Summary

Ginger powder can potentially alleviate cognitive impairment caused by ethanol abuse by regulating NMDA and GABA-A receptors, reducing oxidative damage, and inhibiting the NF-κB/TNF-α/IL-1β pathway in the rat hippocampus.

Wang J et al (2023).
Metab Brain Dis.
PubMed:
37966694

In vitro and in silico prediction of antibacterial interaction between essential oils via graph embedding approach.

Yabuuchi H et al (2023).
Sci Rep.
PubMed:
37919469

Experimental evidence of the neurotoxic effect of monosodium glutamate in adult female Sprague Dawley rats: The potential protective role of Zingiber officinale Rosc. rhizomes.

El-Hashash SA et al (2023).
Saudi J Biol Sci.
PubMed:
37869363

Ultrasound-assisted and subcritical water extraction techniques for maximal recovery of phenolic compounds from raw ginger herbal dust toward in vitro biological activity investigation.

Sulejmanović M et al (2024).
Food Chem.
PubMed:
37866343

An Innovative Approach for Biocontrol of Meloidogyne incognita in Ginger Using Potential Bacteria Isolated from Indian Himalayas.

Kaushal N, Sharma N and Sharma P (2023).
Curr Microbiol.
PubMed:
37864042

The effect of apple pomace powder and calcium ions on selected physicochemical properties of freeze-dried carrot-orange-ginger snacks.

Karwacka M, Galus S and Janowicz M (2024).
J Sci Food Agric.
PubMed:
37851851

Interpretation of the anti-influenza active ingredients and potential mechanisms of Ge Gen Decoction based on spectrum-effect relationships and network analysis.

Liu X et al (2023).
J Ethnopharmacol.
PubMed:
37806538

Ginger beer derived from back-slopping: Volatile compounds, microbial communities on activation and fermentation, metabolites and sensory characteristics.

Iara Gomes de Oliveira L et al (2024).
Food Chem.
PubMed:
37804728

Natural food preservation with ginger essential oil: Biological properties and delivery systems.

Summary

This paper explores the potential of ginger essential oil as a natural food preservative, discussing extraction methods, chemical composition, antibacterial and antioxidant activities, and various applications in food preservation. Ginger essential oil offers effective preservation and improved release control ability, surpassing traditional methods.

He J et al (2023).
Food Res Int.
PubMed:
37803539

Improving Ginger's Bioactive Composition by Combining Innovative Drying and Extraction Technologies.

Dalsasso RR, Valencia GA and Monteiro AR (2023).
Plant Foods Hum Nutr.
PubMed:
37796416

Zingiber officinale rhizome extracts mediated ni nanoparticles and its promising biomedical and environmental applications.

Abdullah et al (2023).
BMC Complement Med Ther.
PubMed:
37789322

Using Ginger Oil to Treat Nausea and Vomiting Following Breast Augmentation Surgery.

Sforza M et al (2023).
Plast Aesthet Nurs (Phila).
PubMed:
37774171

The Effect of Ginger Supplementation on the Improvement of Dyspeptic Symptoms in Patients With Functional Dyspepsia.

Aregawi LG et al (2023).
Cureus.
PubMed:
37771933

Plant derived active compounds of ayurvedic neurological formulation, Saraswatharishta as a potential dual leucine zipper kinase inhibitor: an in-silico study.

Koirala S et al (2023).
J Biomol Struct Dyn.
PubMed:
37771163

Improved sustained-release properties of ginger essential oil in a Pickering emulsion system incorporated in sodium alginate film and delayed postharvest senescence of mango fruits.

Zhang Y et al (2024).
Food Chem.
PubMed:
37769562

Effect of ginger root powder on gastrointestinal bacteria composition, gastrointestinal symptoms, mental health, fatigue, and quality of life: A double-blind placebo-controlled trial.

Crichton M et al (2023).
J Nutr.
PubMed:
37690779

Unraveling the Potential Anti-Severe Acute Respiratory Syndrome Coronavirus 2 Mechanisms of Ginger by Computational Target Fishing.

Summary

This study identified 20 active compounds in ginger that target 18 human proteins and 12 SARS-CoV-2 proteins, suggesting its potential as a treatment for COVID-19. SIGMAR1 and histone deacetylase 2 could be important proteins in this process.

Chen S and Zhang L (2023).
J Med Food.
PubMed:
37682285

Comparative evaluation of the potential anti-spasmodic activity of Piper longum, Piper nigrum, Terminalia bellerica, Terminalia chebula, and Zingiber officinale in experimental animals.

Tiwari BR et al (2023).
Saudi Pharm J.
PubMed:
37576742

Effects of Ocimum basilicum essential oil and ginger extract on serum biochemistry, oxidative stress and gill tissue damage of pearl gentian grouper during simulated live transport.

Fang D et al (2023).
Vet Res Commun.
PubMed:
37572186

Volatile Organic Compounds Emitted by the Biocontrol Agent Pythium oligandrum Contribute to Ginger Plant Growth and Disease Resistance.

Sheikh TMM et al (2023).
Microbiol Spectr.
PubMed:
37534988

Effects of foods and food components on the in vitro bioaccessibility of total arsenic and arsenic species from Hizikia fusiforme seaweed.

Fu Y et al (2023).
Sci Total Environ.
PubMed:
37499825

Ashwagandha (Withania somnifera) and Shunthi (Zingiber officinale) in mild and moderate COVID-19: An open-label randomized controlled exploratory trial.

Summary

Ayurveda treatments used in India during COVID-19 showed positive outcomes in aiding early recovery from the virus.

Singh H et al (2023).
Complement Ther Med.
PubMed:
37482107

Zinc oxide nanoparticles produced by Zingiber officinale ameliorates acute toxoplasmosis-induced pathological and biochemical alterations and reduced parasite burden in mice model.

El-Kady AM et al (2023).
PLoS Negl Trop Dis.
PubMed:
37410712

A mix of ginger phenols exhibits anti‑adipogenic and lipolytic effects in mature adipocytes derived from 3T3‑L1 cells.

Gembe-Olivarez G et al (2023).
Exp Ther Med.
PubMed:
37383373

Ginger (Zingiber officinale Roscoe) preparations for prophylaxis of postoperative nausea and vomiting: A Bayesian network meta-analysis.

Zhao C et al (2023).
J Ethnopharmacol.
PubMed:
37379959

Promising roles of Zingiber officinale roscoe, Curcuma longa L., and Momordica charantia L. as immunity modulators against COVID-19: A bibliometric analysis.

Summary

Study examines therapeutic potential of antioxidant, anti-inflammatory, immune-stimulating plants against SARS-CoV-2. India leads research, proposes herbal blend for COVID-19 treatment and prevention.

Sheikh HI et al (2023).
J Agric Food Res.
PubMed:
37346755

Combining stable isotope, multielement and untargeted metabolomics with chemometrics to discriminate the geographical origins of ginger (Zingiber officinale Roscoe).

Yu DX et al (2023).
Food Chem.
PubMed:
37301043

Evaluation of antioxidant capacity, structure, and surface morphology of ginger (Zingiber officinale) using different extraction methods.

Jorge-Montalvo P, Vílchez-Perales C and Visitación-Figueroa L (2023).
Heliyon.
PubMed:
37251458

The potential therapeutic effect of Nigella sativa and Zingiber officinale extracts versus Nitazoxanide drug against experimentally induced cryptosporidiosis in laboratory mice.

Yahia SH et al (2023).
J Parasit Dis.
PubMed:
37193490

Effect of Jiawei Tongqiao Huoxue decoction in basilar artery dolichoectasia mice through yes-associated protein/transcriptional Co-activator with PDZ-binding motif pathway.

Liu FX et al (2023).
J Ethnopharmacol.
PubMed:
37149070

Evaluation of the Herb-Drug Interaction (HDI) Potential of Zingiber officinale and Its Major Phytoconstituents.

Husain I et al (2023).
J Agric Food Chem.
PubMed:
37134183

Multivariate analysis of original identification and chemical markers exploration of Chinese ginger.

Guo M et al (2023).
Food Sci Biotechnol.
PubMed:
37123069

Antimalarial potential, LC-MS secondary metabolite profiling and computational studies of Zingiber officinale.

Faloye KO et al (2023).
J Biomol Struct Dyn.
PubMed:
37116195

Antibacterial and Antibiofilm Efficacy and Mechanism of Ginger (Zingiber officinale) Essential Oil against Shewanella putrefaciens.

Zhang C et al (2023).
Plants (Basel).
PubMed:
37111943

Gut microbiota-based metabolites of Xiaoyao Pills (a typical Traditional Chinese medicine) ameliorate depression by inhibiting fatty acid amide hydrolase levels in brain.

Summary

XYPs are a commonly used Traditional Chinese Medicine (TCM) for treating depression. However, since they are taken orally, they may interact with gut bacteria and affect the therapeutic outcomes of TCMs. The chemical complexity of XYPs makes understanding their biological effects a challenge.

Zhang ZW et al (2023).
J Ethnopharmacol.
PubMed:
37100263

Preliminary exploration of method for screening efficacy markers compatibility in TCM prescriptions based on Q-markers: Anti-inflammatory activity of Dachaihu decoction as an example.

Bi S et al (2023).
J Ethnopharmacol.
PubMed:
37088240

Antioxidant, antiglycation, and anti-inflammatory activities of Caesalpinia mimosoides.

Rodwattanagul S, Nimlamool W and Okonogi S (2023).
Drug Discov Ther.
PubMed:
37081689

Investigation on the Anticancer Activity of [6]-Gingerol of Zingiber officinale and its Structural Analogs against Skin Cancer.

A M, A P and B MB (2023).
Curr Comput Aided Drug Des.
PubMed:
37076965

Influence of peeling on volatile and non-volatile compounds responsible for aroma, sensory, and nutrition in ginger (Zingiber officinale).

Liang J et al (2023).
Food Chem.
PubMed:
37003052

Effect of Dietary Supplementation of Zinc Nanoparticles Prepared by Different Green Methods on Egg Production, Egg Quality, Bone Mineralization, and Antioxidant Capacity in Caged Layers.

Hassan S et al (2023).
Biol Trace Elem Res.
PubMed:
36997774

Dehydrozingerone enhances the fungicidal activity of glabridin against Saccharomyces cerevisiae and Candida albicans.

Yamano S et al (2023).
Lett Appl Microbiol.
PubMed:
36990694

Evaluation of phytochemicals and antioxidant potential of a new polyherbal formulation TC-16: additive, synergistic or antagonistic?

Yap VL et al (2023).
BMC Complement Med Ther.
PubMed:
36978110

The effect of ginger (Zingiber officinale) supplementation on clinical, biochemical, and anthropometric parameters in patients with multiple sclerosis: a double-blind randomized controlled trial.

Summary

In a randomized, double-blind, placebo-controlled trial, ginger supplementation significantly reduced disability, physical and psychological quality of life, neurofilament light chain, interleukin-17, and neutrophil to lymphocyte ratio in patients with relapsing-remitting multiple sclerosis (MS), but did not affect body mass index or matrix metalloproteinase-9 levels. These findings suggest that ginger may be a promising adjuvant therapy for MS.

Foshati S et al (2023).
Food Funct.
PubMed:
36974730

The Use of D-Optimal Mixture Design in Optimizing Formulation of a Nutraceutical Hard Candy.

Souiy Z et al (2023).
Int J Food Sci.
PubMed:
36968159

Volatile organic compounds of Bacillus pumilus strain S1-10 exhibit fumigant activity against Meloidogyne incognita.

Dai M et al (2023).
Plant Dis.
PubMed:
36916837

Quality assessment of commercial dried ginger (Zingiber officinale Roscoe) based on targeted and non-targeted chemical profiles and anti-inflammatory activity.

He L et al (2023).
Food Res Int.
PubMed:
36914321

The Effect of Ginger (Zingiber officinale Roscoe) Aqueous Extract on Postprandial Glycemia in Nondiabetic Adults: A Randomized Controlled Trial.

Diakos A et al (2023).
Foods.
PubMed:
36900554

Green synthesis and biological evaluation of glaucanic acid and dihydrocompactin acid by endophytic fungus Penicillium polonicum from Zingiber officinale.

Gupta S et al (2023).
Nat Prod Res.
PubMed:
36896764

Oral Administration Evaluation of the Hydro-Ethanolic Extract of Ginger (Rhizome of Zingiber officinale) against Postoperative-Induced Peritoneal Adhesion: Investigating the Role of Anti-Inflammatory and Antioxidative Effects.

Yahyazadeh R et al (2023).
Evid Based Complement Alternat Med.
PubMed:
36865747

[8] and [10]-Gingerol reduces urothelial damage in ifosfamide-induced hemorrhagic cystitis via JAK/STAT/FOXO signaling pathway via IL-10.

Ferreira FCS et al (2023).
Naunyn Schmiedebergs Arch Pharmacol.
PubMed:
36843129

Effects of Ginger on Disgust, Sexual Arousal, and Sexual Engagement: A Placebo-Controlled Experiment.

Wen G et al (2024).
J Sex Res.
PubMed:
36809190

Effect of ginger (Zingiber officinale) intake on human serum lipid profile: Systematic review and meta-analysis.

Review
Salih AK et al (2023).
Phytother Res.
PubMed:
36786398

A comprehensive review on Ginger (Zingiber officinale) as a potential source of nutraceuticals for food formulations: Towards the polishing of gingerol and other present biomolecules.

Review
Garza-Cadena C et al (2023).
Food Chem.
PubMed:
36753787

Bioactivities and green advanced extraction technologies of ginger oleoresin extracts: A review.

Review
Kamaruddin MSH et al (2023).
Food Res Int.
PubMed:
36737895

The effects of Ginger (Zingiber officinale) roots on the reproductive aspects in male Japanese Quails (Coturnix coturnix japonica).

Abdelfattah MG et al (2023).
BMC Vet Res.
PubMed:
36737791

Synergistic effect of Trikatuk, a traditional Thai formulation, on antioxidant and alpha-glucosidase inhibitory activities.

Nutmakul T and Chewchinda S (2023).
Heliyon.
PubMed:
36711300

Biosynthesized silver nanoparticles have anticoccidial and jejunum-protective effects in mice infected with Eimeria papillata.

Dkhil MA et al (2023).
Environ Sci Pollut Res Int.
PubMed:
36694067

Therapeutic health effects of ginger (Zingiber officinale): updated narrative review exploring the mechanisms of action.

Crichton M et al (2023).
Nutr Rev.
PubMed:
36688554

Zingiberene, a non-zinc-binding class I HDAC inhibitor: A novel strategy for the management of neuropathic pain.

Summary

The researchers explored the potential of a rhizome extract from Zingiber officinalis in inhibiting HDAC1 to reduce neuroinflammation. This could lead to more selective and effective treatments for neurodegenerative diseases.

Borgonetti V et al (2023).
Phytomedicine.
PubMed:
36681053

Fusarium Yellows of Ginger (Zingiber officinale Roscoe) Caused by Fusarium oxysporum f. sp. zingiberi Is Associated with Cultivar-Specific Expression of Defense-Responsive Genes.

Prasath D et al (2023).
Pathogens.
PubMed:
36678490

A Comparative Study on Chemical Compositions and Biological Activities of Four Amazonian Ecuador Essential Oils: Curcuma longa L. (Zingiberaceae), Cymbopogon citratus (DC.) Stapf, (Poaceae), Ocimum campechianum Mill. (Lamiaceae), and Zingiber officinale Roscoe (Zingiberaceae).

Guerrini A et al (2023).
Antibiotics (Basel).
PubMed:
36671378

The natural occurrence, toxicity mechanisms and management strategies of Fumonisin B1:A review.

Review
Gao Z et al (2023).
Environ Pollut.
PubMed:
36639041

6-Gingerol contents of several ginger varieties of Northeast India and correlation of their antioxidant activity in respect to phenolics and flavonoids contents.

Ghosh S et al (2023).
Phytochem Anal.
PubMed:
36594354

Revisiting the therapeutic potential of gingerols against different pharmacological activities.

Review
Sharma S et al (2023).
Naunyn Schmiedebergs Arch Pharmacol.
PubMed:
36585999

Two new phenylbutenoids from the rhizomes of cassumunar ginger and their α-glucosidase inhibitory activity.

Le TH et al (2024).
Nat Prod Res.
PubMed:
36576074

Structural Characterization, Rheological Properties, Antioxidant and Anti-Inflammatory Activities of Polysaccharides from Zingiber officinale.

Jing Y et al (2023).
Plant Foods Hum Nutr.
PubMed:
36437417

Compatibility between cold-natured medicine CP and hot-natured medicine AZ synergistically mitigates colitis mice through attenuating inflammation and restoring gut barrier.

Li YY et al (2023).
J Ethnopharmacol.
PubMed:
36395977

Effects of microwave power and hot air temperature on the physicochemical properties of dried ginger (Zingiber officinale) using microwave hot-air rolling drying.

Zeng S et al (2023).
Food Chem.
PubMed:
36332585

Effects of ginger (Zingiber officinale) supplementation on testicular histology, semen characteristic, blood plasma parameters and reproductive performance in aged broiler breeder roosters.

Nemati Z et al (2023).
J Anim Physiol Anim Nutr (Berl).
PubMed:
36245294

Long-term effects of a diet supplement containing Cannabis sativa oil and Boswellia serrata in dogs with osteoarthritis following physiotherapy treatments: a randomised, placebo-controlled and double-blind clinical trial.

Gabriele V et al (2023).
Nat Prod Res.
PubMed:
36067506

Effects of soil waterlogging and high-temperature stress on photosynthesis and photosystem II of ginger (Zingiber officinale).

Liu S et al (2023).
Protoplasma.
PubMed:
35726036

Effect of Sustained Systemic Administration of Ginger (Z officinale) Rhizome Extracts on Salivary Flow in Mice.

Kan CY et al (2023).
Int Dent J.
PubMed:
35725589

Zingiber officinale ameliorates Alzheimer's disease and Cognitive Impairments: Lessons from preclinical studies.

Summary

Alzheimer's disease (AD) is a neurodegenerative condition that causes cognitive impairments. Researchers are searching for new treatments due to the limited efficacy and side effects of current medications. This study evaluated the potential protective properties of the compounds found in ginger against memory impairments. Both in vitro and in vivo studies were conducted, as well as clinical trials. The results demonstrated that ginger and its components have the potential to improve and prevent memory dysfunctions by targeting oxidative stress, neuroinflammation, and apoptosis. However, more studies are required to evaluate their pharmaceutical aspects.

Talebi M et al (2021).
Biomed Pharmacother.
PubMed:
33378982

Ginger (Zingiber officinale Rosc.) and its bioactive components are potential resources for health beneficial agents.

Zhang M et al (2021).
Phytother Res.
PubMed:
32954562

Research Progress on Chemical Constituents of Zingiber officinale Roscoe.

Review
Liu Y, Liu J and Zhang Y (2019).
Biomed Res Int.
PubMed:
31930125

Ginger.

Review
(2022).
PubMed:
30000845

Beneficial effects of ginger Zingiber officinale Roscoe on obesity and metabolic syndrome: a review.

Review Obesity
Wang J et al (2017).
Ann N Y Acad Sci.
PubMed:
28505392

A review of the gastroprotective effects of ginger (Zingiber officinale Roscoe).

Review
Haniadka R et al (2013).
Food Funct.
PubMed:
23612703

Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research.

Ali BH et al (2008).
Food Chem Toxicol.
PubMed:
17950516