Ziziphus jujuba

Ethnobotanical Studies

Studies

The effector SJP3 interferes with pistil development by sustaining SHORT VEGETATIVE PHASE 3 expression in jujube.

Deng M et al (2024).
Plant Physiol.
PubMed:
39189604

Comprehensive analysis of transcriptomics and metabolomics provides insights into the mechanism by plant growth regulators affect the quality of jujube (Ziziphus jujuba Mill.) fruit.

Summary

Study of jujube fruit with plant growth regulators uncovered key genes in flavonoid biosynthesis, potential for fruit quality improvement, and metabolic changes. Gibberellin and indole-3-acetic acid levels rose, while abscisic acid fell, revealing molecular mechanisms.

Liu D et al (2024).
PLoS One.
PubMed:
39178226

Effects of jujube (Ziziphus jujuba mill.) fruit extracts on oxidative stress: A systematic review and meta-analysis of rodent studies.

Summary

Jujube fruit extracts lower oxidative stress markers in rodents. May be useful as antioxidant supplements for diseases with oxidative stress. More research needed due to low study quality.

Review Immunology
Zhu D et al (2024).
Food Sci Nutr.
PubMed:
39139963

The effector PHYL1(JWB) from Candidatus Phytoplasma ziziphi induces abnormal floral development by destabilising flower development proteins.

Xue C et al (2024).
Plant Cell Environ.
PubMed:
39119795

Induction of luteolin on postharvest color change and phenylpropanoid metabolism pathway in winter jujube fruit (Ziziphus jujuba Mill. cv. Dongzao).

Tang Y et al (2024).
Plant Physiol Biochem.
PubMed:
39098186

Electrospun PCL/PVA/PHMB nanofibers incorporating Ziziphus jujuba fruit extract as promising wound dressings with potent antibacterial and antidiabetic properties.

Summary

Electrospun nanofiber wound dressings with PHMB and ZJ fruit extract showed superior antibacterial and antidiabetic effects, accelerating wound healing and reducing inflammation, making them suitable for diabetic patients. Use PCL/PVA/PHMB/ZJ for advanced wound care.

Fahimirad S et al (2024).
J Biomater Sci Polym Ed.
PubMed:
39088278

Functional Nutrients and Jujube-Based Processed Products in Ziziphus jujuba.

Review
Cai W et al (2024).
Molecules.
PubMed:
39065014

Jujuboside A through YY1/CYP2E1 signaling alleviated type 2 diabetes-associated fatty liver disease by ameliorating hepatic lipid accumulation, inflammation, and oxidative stress.

Summary

Ju A, an active component of SZS, protected against liver damage in T2DM by reducing lipid accumulation and inflammation, and enhancing fatty acid metabolism through PPARα activation. Potential treatment for NAFLD.

Zhang W et al (2024).
Chem Biol Interact.
PubMed:
39059604

Integration analysis of miRNA-mRNA pairs between two contrasting genotypes reveals the molecular mechanism of jujube (Ziziphus jujuba Mill.) response to high-temperature stress.

Summary

Researchers studied how jujube plants cope with heat stress at genetic level. Identified miRNAs and mRNAs involved in key pathways. Findings offer insights for breeding heat-tolerant crops.

Jin J et al (2024).
BMC Plant Biol.
PubMed:
38937704

Jujubae Fructus extract prolongs lifespan and improves stress tolerance in Caenorhabditis elegans dependent on DAF-16/SOD-3.

Zhang Z et al (2024).
Sci Rep.
PubMed:
38877105

Performance of spray-dried Ziziphus jujuba extract using insoluble fraction of Persian gum-sodium alginate and whey protein: Microstructural and physicochemical attributes of micro- and nano-capsules.

Khoshdouni Farahani Z et al (2024).
Food Sci Nutr.
PubMed:
38873444

Effects of high-temperature stress on gene expression related to photosynthesis in two jujube (Ziziphus jujuba Mill.) varieties.

Yang L et al (2024).
Plant Signal Behav.
PubMed:
38775124

Chemometric analysis illuminates the relationship among browning, polyphenol degradation, Maillard reaction and flavor variation of 5 jujube fruits during air-impingement jet drying.

Li W et al (2024).
Food Chem X.
PubMed:
38736979

Identification of Key Genes of Fruit Shape Variation in Jujube with Integrating Elliptic Fourier Descriptors and Transcriptome.

Ren Y et al (2024).
Plants (Basel).
PubMed:
38732489

Integrated anatomical structure, physiological, and transcriptomic analyses to identify differential cold tolerance responses of Ziziphus jujuba mill. 'Yueguang' and its autotetraploid 'Hongguang'.

Zhu W et al (2024).
Plant Physiol Biochem.
PubMed:
38714127

Da-Chai-Hu-Tang Formula inhibits the progression and metastasis in HepG2 cells through modulation of the PI3K/AKT/STAT3-induced cell cycle arrest and apoptosis.

Duan ZW et al (2024).
J Ethnopharmacol.
PubMed:
38705430

Author Correction: Cultivation and morphology of jujube (Ziziphus Jujuba Mill.) in the Qi River Basin of Northern China during the Neolithic Period.

Li Y et al (2024).
Sci Rep.
PubMed:
38698110

The 'Candidatus phytoplasma ziziphi' effectors SJP1 and SJP2 destabilise the bifunctional regulator ZjTCP7 to modulate floral transition and shoot branching.

Ma F et al (2024).
Plant Cell Environ.
PubMed:
38623040

First Report of Alternaria alternata Causing Postharvest Fruit Rot of Indian Jujube (Ziziphus mauritiana) in China.

Yang C et al (2024).
Plant Dis.
PubMed:
38616395

Polyphenol Extracts from Ziziphus jujuba Mill. "Junzao" Attenuates Ulcerative Colitis by Inhibiting the NLRP3 and MAPKs Signaling Pathways and Regulating Gut Microbiota Homeostasis in Mice.

Wei X et al (2024).
Mol Nutr Food Res.
PubMed:
38600887

Investigation of the Cognitive Activity Between the Leaf Extracts of Eclipta alba and Ziziphus jujuba in Diabetic Animal Models.

Summary

Study tested ZJ and EA extracts on diabetic rats, showed cognitive improvement in Morris water maze test. Potential cognitive enhancers and hypoglycemic agents in diabetes management.

Annepaka ER et al (2024).
Cureus.
PubMed:
38562322

In vitro antimicrobial and antibiofilm screening of eighteen Iranian medicinal plants.

Summary

Iranian medicinal plants show promising antimicrobial properties, a potential low-cost solution to drug-resistant pathogens with minimal side effects. Crucial for developing new antibiotics.

Hamidi M et al (2024).
BMC Complement Med Ther.
PubMed:
38549139

[Qualitative and semiquantitative analyses of the chemical components of the seed coat and kernel of Ziziphi Spinosae Semen].

Shi YH et al (2024).
Se Pu.
PubMed:
38503700

Sour Jujube (Ziziphus jujuba var. spinosa): A Bibliometric Review of Its Bioactive Profile, Health Benefits and Trends in Food and Medicine Applications.

Review
Ruan W et al (2024).
Foods.
PubMed:
38472749

A natural mutation in the promoter of the aconitase gene ZjACO3 influences fruit citric acid content in jujube.

Liu H et al (2024).
Hortic Res.
PubMed:
38464475

ZjHXK5 and ZjHXK6 negatively regulate the sugar metabolism of Ziziphus jujuba Mill.

Tong P et al (2024).
Front Plant Sci.
PubMed:
38410733

The Sequence Characteristics and Binding Properties of the Odorant-Binding Protein SvelOBP1 from Sympiezomias velatus (Coleoptera: Curculionidae) to Jujube Volatiles.

Zhai Y et al (2024).
Life (Basel).
PubMed:
38398701

Nontargeted metabolomics and enzyme inhibitory and antioxidant activities for chemical and biological characterization of jujube (Ziziphus jujuba) extracts.

Yu YL et al (2024).
J Pharm Biomed Anal.
PubMed:
38387129

Comparative analysis of jujube and sour jujube gave insight into their difference in genetic diversity and suitable habitat.

Shao L et al (2024).
Front Genet.
PubMed:
38380425

The 'Candidatus Phytoplasma ziziphi' effectors SJP1/2 negatively control leaf size by stabilizing ZjTCP2 in jujube.

Ma F et al (2024).
J Exp Bot.
PubMed:
38320293

Improving physicochemical, rheometry and sensory attributes of fortified beverages using jujube alcoholic/aqueous extract loaded Gellan-Protein macrocarriers.

Khoshdouni Farahani Z, Ebrahimzadeh Mousavi M and Ibrahim SA (2024).
Heliyon.
PubMed:
38304791

Cultivation and morphology of jujube (Ziziphus Jujuba Mill.) in the Qi River Basin of Northern China during the Neolithic Period.

Li Y et al (2024).
Sci Rep.
PubMed:
38280899

L-carnitine modified nanoparticles target the OCTN2 transporter to improve the oral absorption of jujuboside B.

Li W et al (2024).
Eur J Pharm Biopharm.
PubMed:
38280469

Potential Parasitoids for Biocontrol of the Ber Fruit Fly, Carpomya vesuviana Costa (Diptera: Tephritidae).

Amini A et al (2023).
Life (Basel).
PubMed:
38255665

Combined Effects of Ziziphus jujuba, Dimocarpus longan, and Lactuca sativa on Sleep-Related Behaviors through GABAergic Signaling.

Bae GY et al (2023).
Foods.
PubMed:
38201029

The Influences of Soil and Meteorological Factors on the Growth and Fruit Quality of Chinese Jujube (Ziziphus jujuba Mill.).

Duan Y et al (2023).
Plants (Basel).
PubMed:
38140434

Spinosin inhibits activated hepatic stellate cell to attenuate liver fibrosis by targeting Nur77/ASK1/p38 MAPK signaling pathway.

Lin G et al (2023).
Eur J Pharmacol.
PubMed:
38096970

DNA barcoding identification of grafted Semen Ziziphi Spinosae and transcriptome study of wild Semen Ziziphi Spinosae.

Summary

Grafting improves Semen Ziziphi Spinosae (SZS) yield and quality. Genetic and transcriptome analysis reveal differences between grafted and wild SZS.

Wu M et al (2023).
PLoS One.
PubMed:
38039317

Hyperspectral estimation of chlorophyll content in jujube leaves: integration of derivative processing techniques and dimensionality reduction algorithms.

Tuerxun N et al (2023).
Front Plant Sci.
PubMed:
38034562

Unprecedented yet gradual nature of first millennium CE intercontinental crop plant dispersal revealed in ancient Negev desert refuse.

Fuks D et al (2023).
Elife.
PubMed:
38011372

Genome-wide analysis of ALDH gene family in jujube and identification of ZjALDH3F3 for its important role in high-temperature tolerance.

Li L et al (2023).
Plant Physiol Biochem.
PubMed:
38000236

The resistance of the jujube (Ziziphus jujuba) to the devastating insect pest Apolygus lucorum (Hemiptera, Insecta) involves the jasmonic acid signaling pathway.

Li Q et al (2023).
Pestic Biochem Physiol.
PubMed:
37945226

Electrophysiological and Behavioral Responses of Plodia interpunctella (Hübner) Females to Aldehyde Volatiles from Dried Fruits.

Zhao J et al (2023).
J Agric Food Chem.
PubMed:
37921278

Visualizing the Distribution of Jujube Metabolites at Different Maturity Stages Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging.

Lu D et al (2023).
Foods.
PubMed:
37893688

Maimendong decoction regulates M2 macrophage polarization to suppress pulmonary fibrosis via PI3K/Akt/FOXO3a signalling pathway-mediated fibroblast activation.

Summary

Mai Men Dong decoction (MMDD), a traditional Chinese medicine, contains herbs known for treating respiratory conditions. Studying MMDD can enhance understanding and development of ethnopharmacology.

Shuangshuang HE et al (2023).
J Ethnopharmacol.
PubMed:
37865276

Suppression of sweet taste-related responses by plant-derived bioactive compounds and eating. Part II: A systematic review in animals.

Rayo-Morales R et al (2023).
Heliyon.
PubMed:
37860570

Interpretation of the anti-influenza active ingredients and potential mechanisms of Ge Gen Decoction based on spectrum-effect relationships and network analysis.

Liu X et al (2023).
J Ethnopharmacol.
PubMed:
37806538

Metabolomics and transcriptomics analyses for characterizing the alkaloid metabolism of Chinese jujube and sour jujube fruits.

Summary

Researchers investigated the synthesis and metabolism of alkaloids in jujube fruits, focusing on Chinese jujube and sour jujube. Understanding these mechanisms could contribute to the economic value and potential benefits of jujube fruits.

Xue X et al (2023).
Front Plant Sci.
PubMed:
37790781

Effect of poly(L-lactic acid)/poly(ethylene glycol)-poly(L-lactic acid) block copolymer blend film on preservation of Chinese winter jujube (Ziziphus Jujuba Mill. cv. Dongzao).

Wang L et al (2023).
Int J Biol Macromol.
PubMed:
37572816

In Vitro Antiproliferative Apoptosis Induction and Cell Cycle Arrest Potential of Saudi Sidr Honey against Colorectal Cancer.

Summary

Sidr honey from Saudi Arabia was tested on colorectal, breast, and lung cancer cells. It showed potential as an antitumor agent by inducing apoptosis and cell cycle arrest. Further research is needed to identify and understand the active compounds.

Qanash H et al (2023).
Nutrients.
PubMed:
37571386

Multiple-Genome-Based Simple Sequence Repeat Is an Efficient and Successful Method in Genotyping and Classifying Different Jujube Germplasm Resources.

Summary

This study developed a new method (MGB-SSR) to rapidly identify genetic variations in jujube plants, allowing for more efficient breeding and classification of jujube germplasm.

Li B et al (2023).
Plants (Basel).
PubMed:
37571038

Sleep-Enhancing Effect of Water Extract from Jujube (Zizyphus jujuba Mill.) Seeds Fermented by Lactobacillus brevis L32.

Bae GY et al (2023).
Foods.
PubMed:
37569133

Anti-inflammatory Effects of Ziziphus Jujube Mill on LPS-induced Acute Lung Injury in Mice.

Summary

Z.J extract reduced inflammation in mice with acute lung injury (ALI) caused by LPS. It decreased inflammatory cells, wet-to-dry ratio, lung damage, and TNF-α levels. Z.J could be a potential therapy for ALI.

Shaban P et al (2023).
Iran J Allergy Asthma Immunol.
PubMed:
37524664

Combined Treatment of Acidic Electrolyzed Water and High-Voltage Electrostatic Field Improves the Storage Quality of Huping Jujube (Ziziphus jujuba Mill. cv. Huping).

Chang X et al (2023).
Foods.
PubMed:
37509854

Genotyping of Jujube (Ziziphus spp.) Germplasm in New Mexico and Southwestern Texas.

Sapkota D et al (2023).
Plants (Basel).
PubMed:
37446967

Jujube witches' broom phytoplasma effector Zaofeng3, a homologous effector of SAP54, induces abnormal floral organ development and shoot proliferation.

Chen P et al (2023).
Phytopathology.
PubMed:
37435950

Sequencing the chloroplast genome of a jujube genotype (Ziziphus jujuba Mill. 'Fengmiguan') uncovered a 101 bp insertion in the large-single copy region.

Zhang S et al (2023).
Mitochondrial DNA B Resour.
PubMed:
37426571

Jujube Fruit Metabolomic Profiles Reveal Cultivar Differences and Function as Cultivar Fingerprints.

Yao S et al (2023).
Plants (Basel).
PubMed:
37375938

Effect on Ziziphus jujuba Mill. fruit powders embedded on physicochemical properties, biological activities, and rheologic quality of cake.

Elaloui M et al (2023).
Food Sci Nutr.
PubMed:
37324873

Pan trapping is an effective method to trap adults of the jujube gall midge, Dasineura jujubifolia (Diptera: Cecidomyiidae).

Wang H et al (2023).
Environ Entomol.
PubMed:
37284820

Hydroalcoholic Extract of Ziziphus Jujuba Leaf to Prevent Ethylene Glycol and Ammonium Chloride-Induced Kidney Stones in Male Rat: Is it Effective?

Pourahmadi M et al (2023).
Urol J.
PubMed:
37245086

The effect of food, vitamin, or mineral supplements on chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.

van der Schoot A et al (2023).
Neurogastroenterol Motil.
PubMed:
37243443

Effect of Jiawei Tongqiao Huoxue decoction in basilar artery dolichoectasia mice through yes-associated protein/transcriptional Co-activator with PDZ-binding motif pathway.

Liu FX et al (2023).
J Ethnopharmacol.
PubMed:
37149070

Comparative transcriptome profiling analysis provides insight into the mechanisms for sugar change in Chinese jujube (Ziziphus jujuba Mill.) under rain-proof cultivation.

Ji Q et al (2023).
Plant Genome.
PubMed:
37144674

Functional characterization, structural basis, and regio-selectivity control of a promiscuous flavonoid 7,4'-di-O-glycosyltransferase from Ziziphus jujuba var. spinosa.

Wang ZL et al (2023).
Chem Sci.
PubMed:
37123177

Transcriptome Characterization of Pigment-Related Genes in Jujube (Ziziphus Jujuba Mill.) Peel at Different Growth Stages.

Li S et al (2023).
Biochem Genet.
PubMed:
37106171

Preliminary exploration of method for screening efficacy markers compatibility in TCM prescriptions based on Q-markers: Anti-inflammatory activity of Dachaihu decoction as an example.

Bi S et al (2023).
J Ethnopharmacol.
PubMed:
37088240

Triterpenoids in Jujube: A Review of Composition, Content Diversity, Pharmacological Effects, Synthetic Pathway, and Variation during Domestication.

Review
Pan F et al (2023).
Plants (Basel).
PubMed:
37050126

Genome-wide characterization of the cellulose synthase gene family in Ziziphus jujuba reveals its function in cellulose biosynthesis during fruit development.

Niu N et al (2023).
Int J Biol Macromol.
PubMed:
37030464

ZjFAS2 is involved in the fruit coloration in Ziziphus jujuba Mill. by regulating anthocyanin accumulation.

Li S et al (2023).
Front Plant Sci.
PubMed:
36968382

Autotetraploidization Alters Morphology, Photosynthesis, Cytological Characteristics and Fruit Quality in Sour Jujube (Ziziphus acidojujuba Cheng et Liu).

Wang L et al (2023).
Plants (Basel).
PubMed:
36903965

The Grade of Dried Jujube (Ziziphus jujuba Mill. cv. Junzao) Affects Its Quality Attributes, Antioxidant Activity, and Volatile Aroma Components.

Wu Z et al (2023).
Foods.
PubMed:
36900506

Transcription Factors ZjMYB39 and ZjMYB4 Regulate Farnesyl Diphosphate Synthase- and Squalene Synthase-Mediated Triterpenoid Biosynthesis in Jujube.

Wen C et al (2023).
J Agric Food Chem.
PubMed:
36880571

Novel Antifungal and Antifeedant Metabolites from Penicillium chrysogenum Co-cultured with Nemania primolutea and Aspergillus fumigatus.

Yang XQ et al (2023).
Chem Biodivers.
PubMed:
36859575

Genomic C-Value Variation Analysis in Jujube (Ziziphus jujuba Mill.) in the Middle Yellow River Basin.

Wu H et al (2023).
Plants (Basel).
PubMed:
36840207

Methyl Jasmonate- and Salicylic Acid-Induced Transcription Factor ZjWRKY18 Regulates Triterpenoid Accumulation and Salt Stress Tolerance in Jujube.

Wen C et al (2023).
Int J Mol Sci.
PubMed:
36835319

Production and characterization of Ziziphus jujuba extract-loaded composite whey protein and pea protein beads based on Na-alginate/IFPG (insoluble fraction of Persian gum).

Khoshdouni Farahani Z et al (2023).
J Sci Food Agric.
PubMed:
36799350

Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo.

Summary

The search for preventive therapies that interrupt the development of Alzheimer's disease (AD) is ongoing. Current therapeutics have limited clinical benefit. To improve the therapeutic efficiency of AD, scientists are exploring molecules targeting multifunction to interact with various pathological components. Herbal medicines with multiplicity of action, such as Bugu-M, have been found to produce cognitive benefits on AD. Bugu-M is a multi-herbal extract composed of various components that confer resilience to cognitive deficits.

Lin NH et al (2023).
J Alzheimers Dis Rep.
PubMed:
36777330

Heavy metal contamination and risk assessment in winter jujube (Ziziphus jujuba Mill. cv. Dongzao).

Xu M et al (2023).
Food Chem Toxicol.
PubMed:
36736610

Research progress of quality control for the seed of Ziziphus jujuba var. spinosa (Bunge) Hu ex H.F. Chow (Suan-Zao-Ren) and its proprietary Chinese medicines.

Review
Gong L et al (2023).
J Ethnopharmacol.
PubMed:
36720435

Genome-wide identification and expression profile analysis of SWEET genes in Chinese jujube.

Yang C et al (2023).
PeerJ.
PubMed:
36684667

Systematic Comparison of Structural Characterization of Polysaccharides from Ziziphus Jujuba cv. Muzao.

Ji X et al (2023).
Molecules.
PubMed:
36677620

Spatiotemporal, physiological and transcriptomic dynamics of wild jujube seedlings under saline conditions.

He A et al (2023).
Tree Physiol.
PubMed:
36617163

Natural Cellulose from Ziziphus jujuba Fibers: Extraction and Characterization.

Amior A et al (2022).
Materials (Basel).
PubMed:
36614725

Novel insight into the evolution of volatile compounds during dynamic freeze-drying of Ziziphus jujuba cv. Huizao based on GC-MS combined with multivariate data analysis.

Gou M et al (2023).
Food Chem.
PubMed:
36608556

Hepatoprotective Effect of Dried Red Jujube Fruit Extract Against Acetaminophen-Induced Acute Hepatotoxicity.

Tedyanto CP, Wihanto L and Hendrata AP (2023).
Cureus.
PubMed:
36606101

Jujuboside B inhibits febrile seizure by modulating AMPA receptor activity.

Summary

The study investigated the potential neuroprotective effects of Jujuboside B (JuB) on febrile seizures in children under the age of five. JuB is a bioactive component found in Ziziphi Spinosae Semen, a Chinese herbal medicine commonly used for insomnia. Results showed that JuB reduced the frequency and duration of febrile seizures in a preclinical mouse model. These findings suggest that JuB has the potential to be used as a treatment for febrile seizures in young children.

Jin B et al (2023).
J Ethnopharmacol.
PubMed:
36549370

Low-acidity ALUMINUM-DEPENDENT MALATE TRANSPORTER4 genotype determines malate content in cultivated jujube.

Zhang C et al (2023).
Plant Physiol.
PubMed:
36271866

Molecular Characterization and Fungicide Sensitivity of Jujube Pathogens Colletotrichum gloeosporioides Sensu Stricto and Colletotrichum nymphaeae in South Korea.

Kang EC et al (2023).
Plant Dis.
PubMed:
35997668

Integrated microRNA and transcriptome profiling reveals the regulatory network of embryo abortion in jujube.

Du J et al (2023).
Tree Physiol.
PubMed:
35972818

Wild Jujube (Ziziphus jujuba var. spinosa): A Review of Its Phytonutrients, Health Benefits, Metabolism, and Applications.

Review
Hua Y et al (2022).
J Agric Food Chem.
PubMed:
35731918

Research advances in bioactive components and health benefits of jujube (Ziziphus jujuba Mill.) fruit.

Review
Lu Y et al (2021).
J Zhejiang Univ Sci B.
PubMed:
34128368

Dingxin Recipe IV attenuates atherosclerosis by regulating lipid metabolism through LXR-α/SREBP1 pathway and modulating the gut microbiota in ApoE(-/-) mice fed with HFD.

Zhang Y et al (2021).
J Ethnopharmacol.
PubMed:
33011372

Experimental and Clinical Pharmacology of Ziziphus jujuba Mills.

Review
Rodríguez Villanueva J and Rodríguez Villanueva L (2017).
Phytother Res.
PubMed:
28084039