Study of jujube fruit with plant growth regulators uncovered key genes in flavonoid biosynthesis, potential for fruit quality improvement, and metabolic changes. Gibberellin and indole-3-acetic acid levels rose, while abscisic acid fell, revealing molecular mechanisms.
Jujube fruit extracts lower oxidative stress markers in rodents. May be useful as antioxidant supplements for diseases with oxidative stress. More research needed due to low study quality.
Electrospun nanofiber wound dressings with PHMB and ZJ fruit extract showed superior antibacterial and antidiabetic effects, accelerating wound healing and reducing inflammation, making them suitable for diabetic patients. Use PCL/PVA/PHMB/ZJ for advanced wound care.
Ju A, an active component of SZS, protected against liver damage in T2DM by reducing lipid accumulation and inflammation, and enhancing fatty acid metabolism through PPARα activation. Potential treatment for NAFLD.
Researchers studied how jujube plants cope with heat stress at genetic level. Identified miRNAs and mRNAs involved in key pathways. Findings offer insights for breeding heat-tolerant crops.
Study tested ZJ and EA extracts on diabetic rats, showed cognitive improvement in Morris water maze test. Potential cognitive enhancers and hypoglycemic agents in diabetes management.
Iranian medicinal plants show promising antimicrobial properties, a potential low-cost solution to drug-resistant pathogens with minimal side effects. Crucial for developing new antibiotics.
Grafting improves Semen Ziziphi Spinosae (SZS) yield and quality. Genetic and transcriptome analysis reveal differences between grafted and wild SZS.
Mai Men Dong decoction (MMDD), a traditional Chinese medicine, contains herbs known for treating respiratory conditions. Studying MMDD can enhance understanding and development of ethnopharmacology.
Researchers investigated the synthesis and metabolism of alkaloids in jujube fruits, focusing on Chinese jujube and sour jujube. Understanding these mechanisms could contribute to the economic value and potential benefits of jujube fruits.
Sidr honey from Saudi Arabia was tested on colorectal, breast, and lung cancer cells. It showed potential as an antitumor agent by inducing apoptosis and cell cycle arrest. Further research is needed to identify and understand the active compounds.
This study developed a new method (MGB-SSR) to rapidly identify genetic variations in jujube plants, allowing for more efficient breeding and classification of jujube germplasm.
Z.J extract reduced inflammation in mice with acute lung injury (ALI) caused by LPS. It decreased inflammatory cells, wet-to-dry ratio, lung damage, and TNF-α levels. Z.J could be a potential therapy for ALI.
The search for preventive therapies that interrupt the development of Alzheimer's disease (AD) is ongoing. Current therapeutics have limited clinical benefit. To improve the therapeutic efficiency of AD, scientists are exploring molecules targeting multifunction to interact with various pathological components. Herbal medicines with multiplicity of action, such as Bugu-M, have been found to produce cognitive benefits on AD. Bugu-M is a multi-herbal extract composed of various components that confer resilience to cognitive deficits.
The study investigated the potential neuroprotective effects of Jujuboside B (JuB) on febrile seizures in children under the age of five. JuB is a bioactive component found in Ziziphi Spinosae Semen, a Chinese herbal medicine commonly used for insomnia. Results showed that JuB reduced the frequency and duration of febrile seizures in a preclinical mouse model. These findings suggest that JuB has the potential to be used as a treatment for febrile seizures in young children.