Review

Gastrodia elata Blume (Tianma): Hope for Brain Aging and Dementia.

Physician-scientists are searching for new ways to treat aging-related diseases like dementia. Traditional Chinese medicine (TCM) may provide a promising approach. One TCM, Blume (tianma), has been studied for treating cerebrocardiovascular diseases (CCVDs) like Alzheimer's disease (AD). Studies examined its potential efficacy and safety in well-characterized aging-related disease models, with positive results. Other related herbal preparations and natural products have also shown potential in treating CCVDs and dementia. Overall, data suggest that tianma treatment could be a promising complementary therapy for AD.

Heese K et al (2020).
Evid Based Complement Alternat Med.
PubMed:
33424999

Zingiber officinale ameliorates Alzheimer's disease and Cognitive Impairments: Lessons from preclinical studies.

Alzheimer's disease (AD) is a neurodegenerative condition that causes cognitive impairments. Researchers are searching for new treatments due to the limited efficacy and side effects of current medications. This study evaluated the potential protective properties of the compounds found in ginger against memory impairments. Both in vitro and in vivo studies were conducted, as well as clinical trials. The results demonstrated that ginger and its components have the potential to improve and prevent memory dysfunctions by targeting oxidative stress, neuroinflammation, and apoptosis. However, more studies are required to evaluate their pharmaceutical aspects.

Talebi M et al (2021).
Biomed Pharmacother.
PubMed:
33378982