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This abstract discusses the potential use of Ginkgo biloba extract (GBE) in the prevention of Alzheimer's disease (AD). GBE is a popular herbal remedy taken by elderly people to improve memory and cognitive function. However, its effectiveness in the prevention and treatment of dementia is controversial. The review summarizes recent advancements on the study of the antioxidant properties of GBE in the prevention of AD, including its potential use in patients who are already undergoing conventional anti-dementia treatments. Understanding the mechanisms of action of GBE against AD will help to design therapeutic strategies and gain a better understanding of the underlying neurodegenerative processes.