Review

Antioxidant Properties of Crocus Sativus L. and Its Constituents and Relevance to Neurodegenerative Diseases; Focus on Alzheimer's and Parkinson's Disease.

In this study, researchers investigated the effects of the medicinal plant Crocus Sativus L. on reactive oxygen-nitrogen species, which are produced during cellular reactions. They found that certain compounds in the plant were able to reduce these harmful species, potentially providing a protective effect against oxidative stress. This study highlights the potential benefits of using medicinal plants as natural remedies for oxidative stress-related diseases.

Hatziagapiou K et al (2019).
Curr Neuropharmacol.
PubMed:
29564976

A Review on Central Nervous System Effects of Gastrodin.

Gastrodin, a compound found in the Chinese herb , has been traditionally used for treating various disorders. Recent studies have investigated its effects on the central nervous system (CNS) and found that it has beneficial effects on diseases such as epilepsy, Alzheimer's disease, and Parkinson's disease through several mechanisms. These mechanisms include modulating neurotransmitters, antioxidative and anti-inflammatory effects, and regulating neurotrophins. Despite the promising preclinical data, more clinical studies are needed to determine its effectiveness in treating neurological disorders.

Liu Y et al (2018).
Front Pharmacol.
PubMed:
29456504

The potential role of herbal products in the treatment of Parkinson's disease.

Parkinson's disease (PD) is a disease of the nervous system that causes loss of certain brain cells, leading to movement problems like tremors or stiffness. It may be caused by oxidative stress and an imbalance of reactive oxygen species (ROS). Certain herbal products may contain compounds that act as antioxidants and could be helpful in treating PD. This review summarized the active compounds present in herbal extracts including Baicalei, Curcuma longa, and Paeoniae Alba Radix, among others. These extracts could be useful for designing future treatments for PD.

Amro MS et al (2018).
Clin Ter.
PubMed:
29446788