Review

Nigella sativa L. and its bioactive and nutraceutical components in the management of diabetic peripheral neuropathy.

NS (black cumin) shows promise in reducing inflammation and oxidative stress associated with diabetic neuropathy. Research suggests potential benefits for treating complications of diabetes with fewer side effects.

Khodaie SA et al (2024).
Inflammopharmacology.
PubMed:
39143432

Effects of jujube (Ziziphus jujuba mill.) fruit extracts on oxidative stress: A systematic review and meta-analysis of rodent studies.

Jujube fruit extracts lower oxidative stress markers in rodents. May be useful as antioxidant supplements for diseases with oxidative stress. More research needed due to low study quality.

Zhu D et al (2024).
Food Sci Nutr.
PubMed:
39139963

Addressing GI Health Through the Bidirectional Modulation of the Gut-Brain Axis With Herbal Extracts: A Narrative Review.

Researchers studied the impact of functional constipation on quality of life and mental health. The gut-brain axis plays a role in functional gastrointestinal disorders. Traditional treatments have limitations, leading to interest in herbal supplements like ashwagandha and okra for symptom management.

Evans C and Kalman D (2024).
Cureus.
PubMed:
39139804

A critical review on Moringa oleifera: current status, physicochemical attributes, and food industrial applications.

"Moringa, a plant rich in nutrients and bioactive compounds, has been traditionally used to treat various illnesses. Recent studies highlight its potential as a natural alternative to conventional medications. Researchers should explore its benefits in ethnomedicine and other domains."

Jaglan P et al (2024).
Nat Prod Res.
PubMed:
39135442

Development of semisynthetic saponin immunostimulants.

Extensive structure-activity-relationship studies on natural saponins reveal that replacing ester side chains with amide side chains could generate potent immunostimulants. This research led to the discovery of VSA-1 and VSA-2, which could offer new options for immunostimulatory adjuvants.

Bai D, Kim H and Wang P (2024).
Med Chem Res.
PubMed:
39132259

Acute phase response and oxidative stress in coccidiosis: A review in domestic animals.

Researchers studied the role of oxidative stress and acute phase response in coccidiosis in various animals. Dietary additives like Curcuma longa can reduce oxidative damage and improve antioxidant levels. More research is needed for other animal species.

Razavi SM et al (2024).
Vet Parasitol.
PubMed:
39128326

Synergistic enhancement: Exploring the potential of piperine in cancer therapeutics through chemosensitization and combination therapies.

Piperine from black pepper shows potential in overcoming drug resistance in cancer cells by targeting key pathways and enhancing drug bioavailability. It can improve the effectiveness of chemotherapy when used with other agents.

Manickasamy MK et al (2024).
Life Sci.
PubMed:
39117139

Polygonatum sibiricum polysaccharide regulation of gut microbiota: A viable approach to alleviate cognitive impairment.

Polygonatum sibiricum polysaccharide (PSP) improves gut health, reduces inflammation, and may alleviate cognitive impairment by modulating gut-brain axis communication. Important for understanding and treating neurological diseases.

Jiang Y et al (2024).
Int J Biol Macromol.
PubMed:
39111476