Physicochemical, Nutritional, and Medicinal Properties of Opuntia ficus-indica (L.) Mill. and Its Main Agro-Industrial Use: A Review.
- Martins M, Ribeiro MH and Almeida CMM (2023).
- Plants (Basel).
- PubMed:
- 37050137
A review of 41 studies found that adaptogens, particularly St. John's Wort and saffron, may be effective non-pharmacological strategies for depression. The studies suggest that adaptogens reduce allostatic load via the regulation of BDNF. However, there is limited research on combining adaptogens with physical exercise. The review provides support for the use of St. John's Wort and saffron in depression treatment and highlights the need for more research on the efficacy of other adaptogens and the combination of herbal extracts and resistance training.
Synthetic cathinones (SCs) are the second largest class of new psychoactive substances (NPS) monitored by the EU Early Warning System. They have similar structure to cathinone and cause various neurological events, including increased alertness, mild agitation, severe psychosis, hyperthermia, and death. A systematic literature search was conducted, and 76 studies were included in the present review, highlighting neurotoxic mechanisms and toxic effects on animals and humans. Adverse effects include encephalopathy, coma, convulsions, and hallucinogenic toxidromes, as well as excited/agitated delirium syndrome and serotonin syndrome. These findings suggest that synthetic cathinones pose a significant public health and forensic toxicology challenge.