Review

A review on Plant based remedies for the treatment of Multiple Sclerosis.

Multiple Sclerosis (MS) is a degenerative autoimmune disease with an unknown cause that affects the central nervous system. Currently, there are 18 FDA-approved drugs that modify MS symptoms, but the prolonged use of synthetic drugs has negative effects. Medicinal plants such as Nigella sativa, ginger, saffron, pomegranate, curcumin, resveratrol, and ginsenoside have the potential to improve symptoms and possibly prevent progression of MS. This article aims to inform chronically ill patients about the complementary and alternative medicinal options available to them.

Alam MZ et al (2023).
Ann Pharm Fr.
PubMed:
36963654

Stachydrine, a potential drug for the treatment of cardiovascular system and central nervous system diseases.

Researchers have conducted a review on the traditional Chinese herb, Leonurus japonicus Houtt, and its primary component, stachydrine, which has been shown to have biological activities such as anti-inflammatory, antioxidant, anti-coagulant, anti-apoptotic, vasodilator, and angiogenic promoter. The herb is commonly used in China for gynecological and blood-related disorders, and has unique advantages in the prevention and treatment of cardiovascular disease (CVD). The study aims to provide a scientific basis for the development of new CVD drug formulations.

Liao L et al (2023).
Biomed Pharmacother.
PubMed:
36940619

Cannabinoids in traumatic brain injury and related neuropathologies: preclinical and clinical research on endogenous, plant-derived, and synthetic compounds.

Traumatic brain injury can have debilitating consequences, with even mild injuries leaving approximately 20% of patients with persistent symptoms. Current pharmaceutical interventions have not improved outcomes after TBI. Research has focused on the endocannabinoid system and the therapeutic benefits of cannabis, including cannabinoids and terpenes. Cannabinoids interact with neurons, microglia, and astrocytes, exerting anti-inflammatory and neuroprotective effects that are desirable for TBI management. This review comprehensively appraises the scientific literature on phytocannabinoids, synthetic and endogenous cannabinoids, and terpenes in TBI and other neurological conditions.

Lins BR et al (2023).
J Neuroinflammation.
PubMed:
36935484