Review

Pharmacological, Neurochemical, and Behavioral Mechanisms Underlying the Anxiolytic- and Antidepressant-like Effects of Flavonoid Chrysin.

Chrysin, a natural molecule found in plants, has various health benefits such as antioxidant, anti-inflammatory, anti-cancer, neuroprotective, and anti-apoptotic effects. Researchers have found that chrysin also exhibits anxiolytic and antidepressant-like effects through its interaction with neurotransmitter systems, particularly the GABAergic and serotonergic, and activation of neurotrophic factors. The antioxidant and anti-inflammatory activities of chrysin may also contribute to its therapeutic use for anxiety and depression disorders. These pre-clinical findings suggest that chrysin could be a promising novel therapy for these disorders.

Rodríguez-Landa JF et al (2022).
Molecules.
PubMed:
35684488