Phytochemicals From Vicia faba Beans as Ligands of the Aryl Hydrocarbon Receptor to Regulate Autoimmune Diseases.
- Méndez-López LF et al (2022).
- Front Nutr.
- PubMed:
- 35308285
St. John's wort is a plant with bioactive compounds that have been found to have therapeutic effects on psychiatric and mood disorders such as PTSD, ADHD, OCD, and anxiety. This review study discusses the role of St. John's wort in modulating depression, with respect to changes in neurotransmitter levels in the brain. The study concludes that changes in neurotransmitter levels in depression are complex and that St. John's wort can have inconsistent effects on them. Future studies should focus on studying glutamate and acetylcholine as important neurotransmitters to understand in depression, and on the dualistic modulation of cholinergic signaling induced by St. John's wort.