Fighting antimicrobial resistance (AMR): Chinese herbal medicine as a source of novel antimicrobials - an update.
- Millar BC, Rao JR and Moore JE (2021).
- Lett Appl Microbiol.
- DOI:
- 10.1111/lam.13534
- PubMed:
- 34219247
Vine leaves contain bioactive compounds with antiviral properties against human pathogens. Researchers evaluated the phenolic composition and antiviral activity of leaf extract against Herpes simplex virus type 1 (HSV-1) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). HPLC-MS/MS analysis identified 40 phenolic compounds in the extract, including quercetin derivatives, luteolin, kaempferol, and apigenin. The extract inhibited both viruses at a low concentration of 10 μg/mL. These findings suggest natural extracts could be used in antiviral drugs and future vaccines.