Antimicrobial Studies

Exploring the wound healing activity of phytosomal gel of Annona squamosa and Cinnamomum tamala leaves ethanolic extracts with antioxidant and antimicrobial activities in S aureus infected excision wound model.

Researchers combined ethanolic extracts of two plants to create a Polyherbal Ethanolic extract (PHEE) with antioxidant and antimicrobial properties. PHEE incorporated in a gel showed improved wound healing and reduced bacterial load in infected wounds, outperforming Povidone iodine ointment.

AntimicrobialImmunology Annona squamosaCinnamomum tamala
Khan AD et al (2024).
J Biomater Sci Polym Ed.
DOI:
10.1080/09205063.2024.2382540
PubMed:
39067021

Phytochemical Analysis and Evaluation of Antioxidant and Antimicrobial Properties of Essential Oils and Seed Extracts of Anethum graveolens from Southern Morocco: In Vitro and In Silico Approach for a Natural Alternative to Synthetic Preservatives.

Researchers analyzed the chemical composition of anise seeds from Morocco, finding high levels of antioxidants and antimicrobial properties. The compounds in the seeds show potential as natural alternatives to synthetic preservatives.

AntimicrobialImmunologyPhytochemistry Anethum graveolens
Hadi N et al (2024).
Pharmaceuticals (Basel).
DOI:
10.3390/ph17070862
PubMed:
39065713

The Antiviral Potential of Perilla frutescens: Advances and Perspectives.

In this systematic review, researchers found that has strong antiviral properties. Its active ingredients may inhibit virus replication and spread, offering potential for new antiviral drugs.

Antimicrobial Perilla frutescens
Chen J et al (2024).
Molecules.
DOI:
10.3390/molecules29143328
PubMed:
39064906

Ocimum basilicum and Lagenaria siceraria Loaded Lignin Nanoparticles as Versatile Antioxidant, Immune Modulatory, Anti-Efflux, and Antimicrobial Agents for Combating Multidrug-Resistant Bacteria and Fungi.

Lignin nanoparticles show strong antimicrobial and antifungal activity, lower efflux pump gene expression, and improve blood and organ parameters in rats. They can be used for drug delivery and treating Salmonella and fungal infections.

AntimicrobialImmunology Lagenaria siceraria
El-Samahy LA et al (2024).
Antioxidants (Basel).
DOI:
10.3390/antiox13070865
PubMed:
39061933

Phyllanthus niruri Linn.: Antibacterial Activity, Phytochemistry, and Enhanced Antibiotic Combinatorial Strategies.

Study investigated antibacterial activity of Linn. plant extracts against resistant pathogens. Aqueous and methanolic extracts showed promise in inhibiting bacterial growth, indicating potential for novel antibiotic development. Further research needed.

AntimicrobialPhytochemistry Phyllanthus niruri
Tiwana G, Cock IE and Cheesman MJ (2024).
Antibiotics (Basel).
DOI:
10.3390/antibiotics13070654
PubMed:
39061336

Unveiling the Antimicrobial, Anti-Biofilm, and Anti-Quorum-Sensing Potential of Paederia foetida Linn. Leaf Extract against Staphylococcus aureus: An Integrated In Vitro-In Silico Investigation.

Study demonstrates the antimicrobial potential of Linn. plant extract against biofilm-forming pathogens, including MRSA, through interference with quorum sensing. Bioactive compounds quercetin and kaempferol show promise, but drug-like properties need further investigation for potential as novel therapeutics against antimicrobial resistance.

Antimicrobial Paederia foetida
Santajit S et al (2024).
Antibiotics (Basel).
DOI:
10.3390/antibiotics13070613
PubMed:
39061295

Disinfectant efficacy of glabridin against dried and biofilm cells of Listeria monocytogenes and the impact of residual organic matter.

Glabridin from liquorice roots effectively disinfects L. monocytogenes, especially on stainless steel surfaces. Efficacy may vary with different food residues. Potential as a natural surface disinfectant.

Antimicrobial Glycyrrhiza glabra
Bombelli A et al (2024).
Food Res Int.
DOI:
10.1016/j.foodres.2024.114613
PubMed:
39059895

Unmasking the Antifungal Activity of Anacardium occidentale Leaf Extract against Candida albicans.

Cashew leaf extract showed promising antifungal activity against drug-resistant strains of Candida. It works by inducing oxidative stress and disrupting cellular processes without being toxic. Recommended for further development as a treatment for invasive fungal infections.

Antimicrobial Anacardium occidentale
Quejada LF et al (2024).
J Fungi (Basel).
DOI:
10.3390/jof10070464
PubMed:
39057348
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