GeoBotanical: Arthritis Studies

105.

Safranal inhibits estrogen-deficiency osteoporosis by targeting Sirt1 to interfere with NF-κB acetylation.

Safranal, derived from Saffron, has anti-inflammatory properties. Its role in osteoporosis, a bone disease in menopause, and its effect on osteoclasts regulated by NF-κB signaling is unknown.

Arthritis Endocrinology Immunology Crocus sativus

Sheng SR et al (2023).; Phytomedicine.
DOI:: 10.1016/j.phymed.2023.154739
PubMed:: 37004404

106.

Chinese herbal compound Huangqin Qingrechubi capsule reduces lipid metabolism disorder and inflammatory response in gouty arthritis via the LncRNA H19/APN/PI3K/AKT cascade.

Arthritis Immunology Scutellaria baicalensis

Zhang X et al (2023).; Pharm Biol.
DOI:: 10.1080/13880209.2023.2191641
PubMed:: 36994890

107.

Efficacy and safety of TCMs with anti-inflammatory effect in patients with rheumatoid arthritis: A network meta-analysis.

This study analyzed the effectiveness and safety of Traditional Chinese Medicines (TCMs) for treating rheumatoid arthritis. TCMs have anti-inflammatory effects and are widely used in China.

Arthritis Immunology Glycyrrhiza uralensis

Fang J et al (2023).; Front Immunol.
DOI:: 10.3389/fimmu.2023.1114930
PubMed:: 36969172

108.

Periplocin targets low density lipoprotein receptor-related protein 4 to attenuate osteoclastogenesis and protect against osteoporosis.

Arthritis Periploca forrestii

Zhang X et al (2023).; Biochem Pharmacol.
DOI:: 10.1016/j.bcp.2023.115516
PubMed:: 36966936

109.

Decipher the pharmacological mechanisms of raw and wine-processed Curculigo orchioides Gaertn. on bone destruction in rheumatoid arthritis rats using metabolomics.

Arthritis Curculigo orchioides Curculigo orchioides Gaertn.

Liu X et al (2023).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2023.116395
PubMed:: 36958673

110.

Identification of kukoamine a as an anti-osteoporosis drug target using network pharmacology and experiment verification.

Arthritis Lycium chinense

Luo L et al (2023).; Mol Med.
DOI:: 10.1186/s10020-023-00625-6
PubMed:: 36941586

111.

Component identification of modified sanmiao pills by UPLC-Xevo G2-XS QTOF and its anti-gouty arthritis mechanism based on network pharmacology and experimental verification.

Arthritis Cyathula officinalis Smilax glabra

Chen R et al (2023).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2023.116394
PubMed:: 36940736

112.

Anti-arthritis Effects of Zingiberaceae Extracts on Models of Inflammatory Joint Disease.

Arthritis Immunology Curcuma longa Zingiber officinale

Kongdang P et al (2023).; Planta Med.
DOI:: 10.1055/a-2044-9129
PubMed:: 36940710