Cancer Studies

Mechanistic insights into Retama raetam's anti-proliferative and pro-apoptotic effects in A549 lung cancer cells: targeting PI3K/Akt pathway and ROS production.

Study on effects of tropical desert plant extract on NSCLC cells. Results show dose-dependent anti-proliferative effects, apoptosis induction, inhibition of cell migration, and interaction with PI3K/Akt pathways to promote cell death.Important for potential treatment of lung cancer.

Cancer Retama raetam
Alshehri MA et al (2024).
Toxicol Res (Camb).
DOI:
10.1093/toxres/tfae137
PubMed:
39233844

Chemical Compositions, Molecular Docking, Anti-Inflammatory, and Anti-Cancer Effects of the Leaf Essential Oils Isolated from Three Species of the Rutaceae Family in Vietnam.

Three Rutaceae essential oils, A. pedunculata and E. lepta are strong anti-cancer, while E. lepta is highly anti-inflammatory. Potential medicines for cancer and inflammation.

CancerImmunology Acronychia pedunculata
Pham TV et al (2024).
Chem Biodivers.
DOI:
10.1002/cbdv.202401466
PubMed:
39230662

Effects of Arborvitae (Thuja plicata) Essential Oil on Cervical Cancer Cells: Insights into Molecular Mechanisms.

Study tested effects of AEO on cervical cancer cell lines, HeLa and SiHa. Found AEO's cytotoxic properties and gene expression modulation. Important for potential cancer treatment.

CancerPhytochemistry Thuja plicata
Piña-Cruz R et al (2024).
Anticancer Agents Med Chem.
DOI:
10.2174/0118715206308864240823095507
PubMed:
39229997

Belamcanda chinensis extract inhibits non-small cell lung cancer proliferation and induces apoptosis via inhibiting the MAPK (Ras/Raf) and Akt pathways.

BCE from traditional Chinese medicine inhibits NSCLC cell growth by inducing apoptosis and blocking key signaling pathways, suggesting potential as a treatment for NSCLC, particularly in patients with Ras or Raf mutations.

CancerImmunology Belamcanda chinensis
Ma C et al (2024).
Heliyon.
DOI:
10.1016/j.heliyon.2024.e36032
PubMed:
39229537

A comparative anticancer analysis of Iron Oxide nanoparticles of Hippophae rhamnoides and Cichorium intybus found in the Karakoram Range of Gilgit Baltistan against liver cancer targeting the RhoA gene.

Researchers evaluated FeO nanoparticles from different plant extracts against liver cancer cells. FeO nanoparticles from plant X were most effective, decreasing gene/protein levels of X and increasing levels of Y and Z. This information could lead to new treatments for liver cancer.

CancerGenetics Cichorium intybusHippophae rhamnoides
Tabassum R and Dilshad E (2024).
Drug Dev Ind Pharm.
DOI:
10.1080/03639045.2024.2400209
PubMed:
39226126

Brucea javanica Seed Oil Emulsion and Shengmai Injections Improve Peripheral Microcirculation in Treatment of Gastric Cancer.

Researchers studied the effects of two herbal injections on blood flow in gastric cancer patients. YDZI and SMI may improve circulation, potentially aiding in GC treatment.

CancerGastroenterology Brucea javanica
Quan L et al (2024).
Chin J Integr Med.
DOI:
10.1007/s11655-024-4103-z
PubMed:
39225883

An In-depth Review on Argemone mexicana in the Management of Liver Health and Liver Cancer.

Researchers studied the Mexican prickly poppy for its liver benefits due to the increasing rates of liver diseases. This review highlights its potential for liver health and cancer prevention.

Cancer Argemone mexicana
Saraswat I, Goel A and Gupta J (2024).
Anticancer Agents Med Chem.
DOI:
10.2174/0118715206307964240821051756
PubMed:
39225208

Analysis of Anticancer Taxanes in Turkish Hazelnut (Corylus avellana L.) Genotypes Using High-Performance Liquid Chromatography.

Study investigated anticancer taxane profiles in different Turkish hazelnut genotypes. Hazelnut is a nutrient-rich food linked to decreased heart disease and cancer risk. Turkish hazelnut could be a valuable source of taxanes for pharmaceutical and food industries.

CancerPhytochemistry Corylus avellana
Kutlutürk GZ et al (2024).
Turk J Pharm Sci.
DOI:
10.4274/tjps.galenos.2023.98572
PubMed:
39224934
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