Cancer Studies

Synthesis of a new sulfadimidine Schiff base and their nano complexes as potential anti-COVID-19 and anti-cancer activity.

Researchers synthesized a novel ligand and used it to create nanocomplexes with chromium and copper in an environmentally friendly manner. They analyzed the structure and properties of the complexes using various techniques and found them to be more stable than the free ligand. The chromium nanocomplex showed strong antitumor activity after being heated, while the copper nanocomplex exhibited good DNA cleavage. Molecular docking was used to study the potential of the complexes to bind to liver cancer and COVID-19 proteins.

Hosny S, Ragab MS and Abd El-Baki RF (2023).
Sci Rep.
PubMed:
36707628