Lappaol F regulates the cell cycle by activating CDKN1C/p57 in human colorectal cancer cells.
- Yang RY et al (2023).
- Pharm Biol.
- PubMed:
- 36708218
Researchers synthesized a novel ligand and used it to create nanocomplexes with chromium and copper in an environmentally friendly manner. They analyzed the structure and properties of the complexes using various techniques and found them to be more stable than the free ligand. The chromium nanocomplex showed strong antitumor activity after being heated, while the copper nanocomplex exhibited good DNA cleavage. Molecular docking was used to study the potential of the complexes to bind to liver cancer and COVID-19 proteins.