Cancer Studies

Surgical and Oncological Outcomes After Preoperative FOLFIRINOX Chemotherapy in Resected Pancreatic Cancer: An International Multicenter Cohort Study.

van Veldhuisen E et al (2023).
Ann Surg Oncol.
PubMed:
36539580

Comparative efficacy and safety of Chinese medicine injections combined with capecitabine and oxaliplatin chemotherapies in treatment of colorectal cancer: A bayesian network meta-analysis.

Liu S, Zhang K and Hu X (2022).
Front Pharmacol.
PubMed:
36523501

Mitigation of apoptosis-mediated neurotoxicity induced by silver nanoparticles via rutaceae nutraceuticals: P53 activation and Bax/Bcl-2 regulation.

Silver nanoparticles (AgNPs) are widely used in cancer treatment, but their potential neurotoxicity has not been studied. Swiss Albino mice were exposed to two sizes of AgNPs and treated with extracts from leaves, fruits, and seeds. Oxidative stress occurred after AgNP exposure, but treatment with the extracts modulated biomarkers related to apoptosis and neurotoxicity. The study suggests that AgNPs can induce neurotoxicity and genetic changes, but the extracts show promise in mitigating these effects.

Abdel-Megeed RM et al (2022).
Toxicol Rep.
PubMed:
36518464