Codonopsis lanceolata extract prevents hypertension in rats.
- Han AY et al (2018).
- Phytomedicine.
- PubMed:
- 29433673
Hypericum androsaemum L., also known as tutsan, is a plant commonly grown for its ornamental value and has been used in traditional Portuguese and Spanish medicine to treat depression. In this study, researchers tested the water extract of its red berries (WE) in a mouse model of post-stroke depression. They found that the highest dose of WE significantly reduced depression symptoms and increased endogenous antioxidant defenses in the mouse brain. The study identified four bioactive compounds in WE, including shikimic acid and chlorogenic acid. This is the first study to demonstrate the protective effects of WE in post-stroke depression in vivo, which suggests that tutsan may have potential as an alternative treatment for depression.