Covid-19 Studies

Potential of 6'‑hydroxy justicidin B from Justicia procumbens as a therapeutic agent against coronavirus disease 2019.

Researchers have discovered a potential antiviral compound, 6'-HJB, from a traditional Chinese medicine plant, which may be effective against COVID-19 and its variants. This could provide new therapeutic options in addition to vaccines.

Yoo MH et al (2024).
Phytomedicine.
PubMed:
39241386

Eco-friendly synthesis of silver nanoparticles from peel and juice C. limon and their antiviral efficacy against HSV-1 and SARS-CoV-2.

Silver nanoparticles derived from the peel and juice of Citrus limon show promise in inhibiting Coronaviridae and Herpesviridae viruses with low toxicity, potentially offering a safe and effective antiviral strategy.

Dell'Annunziata F et al (2024).
Virus Res.
PubMed:
39181453

In Silico Analysis of Calotropis procera-Derived Phytochemicals Targeting 3CL Proteoase of SARS-CoV-2.

Scientists studied phytochemicals from Calotropis Procera as potential drugs against the main protease (3CLp) of SARS-CoV-2. 11 phytochemicals showed promise with strong binding affinity and reactivity. These compounds could be developed as effective drugs against COVID-19.

Shafique T et al (2024).
Mol Biotechnol.
PubMed:
39177861

Cross-relationship between COVID-19 infection and anti-obesity products efficacy and incidence of side effects: A cross-sectional study.

Study in Alexandria, Egypt showed pandemic led to increased obesity and AOP intake. Examined AOP efficacy/safety and impact on COVID-19 severity. Important for COVID-19 treatment strategies and public health interventions.

El-Mezayen NS et al (2024).
PLoS One.
PubMed:
39173063

Exploration of medicinal plants as potential therapeutics against COVID-19: molecular insights and drug development prospects with other significant medicinal information a retrospective exposition.

Researchers studied medicinal plants for potential COVID-19 treatment. Plants with antioxidant, anti-inflammatory, and immunomodulatory effects were investigated as inhibitors of the virus. This research could lead to effective treatments for COVID-19.

Dilip Bhandare S et al (2024).
J Pharm Pharmacol.
PubMed:
39173011

Predictive Assessment of the Antiviral Properties of Imperata cylindrica against SARS-CoV-2.

Study found plant-derived phytochemicals with high binding affinities to SARS-CoV-2 main protease. Tabanone showed potential as a safe antiviral agent. Further research needed to validate findings for alternative therapeutic options.

Tatsing Foka FE and Tumelo Mufhandu H (2024).
Adv Virol.
PubMed:
39135917

Baicalin ameliorates angiotensin II-induced cardiac hypertrophy and mitogen-activated protein kinase signaling pathway activation: A target-based network pharmacology approach.

Baicalin from Scutellaria baicalensis helps lower blood pressure and protects the heart. Targets related to cardiac hypertrophy and signaling pathways were identified, showing improved cardiac function in mice and cells by reducing cardiac hypertrophy markers and MAPK pathway activation. It can be beneficial for hypertension-related heart issues.

Cheng Y et al (2024).
Eur J Pharmacol.
PubMed:
39127302

Biosensor-based active ingredient recognition system for screening potential small molecular Severe acute respiratory syndrome coronavirus 2 entry blockers targeting the spike protein from Rugosa rose.

Researchers identified gallic acid (GA) and methyl gallate (MG) from Rosa rugosa in Hanchuan zupa granules as inhibitors of the spike receptor-binding domain of SARS-CoV-2. These compounds block virus entry and have potential for COVID-19 treatment.

Yu W et al (2024).
Biomed Chromatogr.
PubMed:
39126351
1 2 11 38