Gastroenterology Studies

Anti-depressive-like and cognitive impairment alleviation effects of Gastrodia elata Blume water extract is related to gut microbiome remodeling in ApoE(-/-) mice exposed to unpredictable chronic mild stress.

Gastrodia elata Blume (GE) is a traditional Chinese treatment for neurological disorders. Recent tests with a water extract of GE showed it can reduce inflammation and enhance social behavior in mice. But, it wasn't known if the extract could also alleviate depression-like symptoms and cognitive issues in mice with gut microbiome problems.

Huang HS et al (2023).
J Ethnopharmacol.
PubMed:
36343797