GeoBotanical: Gastroenterology Studies

993.

Ficus hirta Vahl. Ameliorates Nonalcoholic Fatty Liver Disease through Regulating Lipid Metabolism and Gut Microbiota.

Gastroenterology Ficus hirta

Quan T et al (2022).; Oxid Med Cell Longev.
DOI:: 10.1155/2022/3474723
PubMed:: 35592528

994.

Gnetum montanum extract induces apoptosis by inhibiting the activation of AKT in SW480 human colon cancer cells.

Cancer Gastroenterology Gnetum montanum

Pan X et al (2022).; Pharm Biol.
DOI:: 10.1080/13880209.2022.2063340
PubMed:: 35587342

995.

ACSL4 promotes colorectal cancer and is a potential therapeutic target of emodin.

Cancer Gastroenterology Rheum palmatum

Dai G et al (2022).; Phytomedicine.
DOI:: 10.1016/j.phymed.2022.154149
PubMed:: 35567995

996.

Polygonum tinctorium leaves suppress sodium dextran sulfate-induced colitis through interleukin-10-related pathway.

Gastroenterology Strobilanthes cusia

Asari T et al (2022).; Biochem Biophys Rep.
DOI:: 10.1016/j.bbrep.2022.101272
PubMed:: 35535330

997.

Glycyrrhiza uralensis Fisch. Root-associated microbiota: the multifaceted hubs associated with environmental factors, growth status and accumulation of secondary metabolites.

Gastroenterology Glycyrrhiza uralensis

Chen C et al (2022).; Environ Microbiome.
DOI:: 10.1186/s40793-022-00418-0
PubMed:: 35526053

998.

Protective Effects of Abrus cantoniensis Hance on the Fatty Liver Hemorrhagic Syndrome in Laying Hens Based on Liver Metabolomics and Gut Microbiota.

Gastroenterology Abrus cantoniensis

Liu X et al (2022).; Front Vet Sci.
DOI:: 10.3389/fvets.2022.862006
PubMed:: 35498747

999.

Modulation of GPCR receptors common to gut inflammatory diseases and neuronal disorders, Alzheimer's and Parkinson's diseases as druggable targets through Withania somnifera bioactives: an in silico study.

The gut microbiota's dysbiosis may lead to neurodegenerative diseases like Alzheimer's and Parkinson's due to increased gut and blood-brain barrier permeability. () is a promising plant for treating neurodegenerative diseases and bowel disorders. The researchers identified five proteins and five best lead compounds after molecular docking analysis and simulation studies, revealing HTR1A and HTR7 proteins with the leads Withanolide E and Withanolide A against them, respectively as the most effective targets. Thus by targeting common potential targets, modulation with bioactive compounds present in can result in effective control of these diseases.

Gastroenterology Immunology Neuroscience Withania somnifera

Shukla R et al (2023).; J Biomol Struct Dyn.
DOI:: 10.1080/07391102.2022.2068072
PubMed:: 35491707

1000.

Host and gut microbiome modulate the antiparasitic activity of nectar metabolites in a bumblebee pollinator.

Gastroenterology Arbutus unedo

Koch H et al (2022).; Philos Trans R Soc Lond B Biol Sci.
DOI:: 10.1098/rstb.2021.0162
PubMed:: 35491601